After silencing suppression : miRNA targets strike back
Silvestri, Alessandro (Centre de Recerca en Agrigenòmica)
Bansal, Chandni (Centre de Recerca en Agrigenòmica)
Rubio-Somoza, Ignacio (Centre de Recerca en Agrigenòmica)

Date:	2024
Abstract:	Within the continuous tug-of-war between plants and microbes, RNA silencing stands out as a key battleground. Pathogens, in their quest to colonize host plants, have evolved a diverse arsenal of silencing suppressors as a common strategy to undermine the host's RNA silencing-based defenses. When RNA silencing malfunctions in the host, genes that are usually targeted and silenced by microRNAs (miRNAs) become active and can contribute to the reprogramming of host cells, providing an additional defense mechanism. A growing body of evidence suggests that miRNAs may act as intracellular sensors to enable a rapid response to pathogen threats. Herein we review how plant miRNA targets play a crucial role in immune responses against different pathogens.
Grants:	Agencia Estatal de Investigación RTI2018-097262-B-I00 Agencia Estatal de Investigación TED2021-131955B-100 Ministerio de Economía y Competitividad SEV-2015-0533 Agencia Estatal de Investigación CEX2019-000902-S European Commission 945043
Note:	Altres ajuts: CERCA Programme/Generalitat de Catalunya
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article de revisió ; recerca ; Versió acceptada per publicar
Subject:	Mirna ; Silencing suppressor ; Pathogen ; Immunity
Published in:	Trends in Plant Science, Vol. 29, Issue 11 (November 2024) , p. 1266-1276, ISSN 1360-1385

DOI: 10.1016/j.tplants.2024.05.001

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
Articles > Published articles