Trait impulsivity and cognitive domains involving impulsivity and compulsivity as predictors of gambling disorder treatment response
Mallorquí-Bagué, Núria (Hospital Universitari de Bellvitge)
Mestre-Bach, Gemma (Hospital Universitari de Bellvitge)
Lozano Madrid, María (Hospital Universitari de Bellvitge)
Fernández Aranda, Fernando (Hospital Universitari de Bellvitge)
Granero, Roser (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut)
Vintró Alcaraz, Cristina (Hospital Universitari de Bellvitge)
Del Pino Gutiérrez, Amparo (Hospital Universitari de Bellvitge)
Steward, Trevor (Hospital Universitari de Bellvitge)
Gomez-Peña, Monica (Hospital Universitari de Bellvitge)
Aymamí, Neus (Hospital Universitari de Bellvitge)
Mena Moreno, Teresa (Hospital Universitari de Bellvitge)
Menchón Magriñá, José Manuel (Hospital Universitari de Bellvitge)
Jiménez-Murcia, Susana (Hospital Universitari de Bellvitge)
Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut

Data:	2018
Resum:	Gambling disorder (GD) is a highly heterogeneous condition with high rates of chronicity, relapses and treatment dropout. The aim of this study was to longitudinally explore the associations between trait impulsivity, impulsivity-compulsivity related cognitive domains, and treatment outcome in an outpatient sample of adult patients with GD. Methods: 144 adult male participants diagnosed with GD undergoing cognitive-behavioural treatment (CBT) at a specialized outpatient service completed a series of neuropsychological tests to assess executive functioning (including cognitive flexibility, inhibition control and decision making) and psychometric questionnaires. Results: Trait impulsivity predicted low compliance [UPPS-P negative urgency (B = 0. 113; p = 0. 019)] and relapse [UPPS-P negative urgency (B = 0. 140; p = 0. 015)] at 5 weeks of treatment and dropout at the end of treatment [(UPPS-P sensation seeking B = 0. 056; p = 0. 045)]. Cognitive flexibility performance predicted: dropout rates at the end of treatment [WCST perseverative errors (B = 0. 043; p = 0. 042)]; dropout [WCST categories completed (B = -1. 827; p = 0. 020)] and low compliance or relapses at follow-up [WCST perseverative errors (B = 0. 128; p = 0. 020)]; and time to first relapse [WCST failure to maintain set (B = -0. 374; p = 0. 048)] and time to dropout [WCST perseverative errors (B = 0. 0198; p = 0. 019)]. Conclusions: Our findings indicate impulsivity-compulsivity levels may influence response to GD treatment (i. e. : low compliance and dropout or relapse rates) thus representing a potential target for improving treatment outcomes.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Matèria:	Cognitive flexibility ; Compulsivity ; Gambling disorder ; Impulsivity ; Inhibitory control ; Treatment
Publicat a:	Addictive behaviors, Vol. 87 (2018) , p. 169-176, ISSN 1873-6327

DOI: 10.1016/j.addbeh.2018.07.006
PMID: 30048796

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