Trait impulsivity and cognitive domains involving impulsivity and compulsivity as predictors of gambling disorder treatment response
Mallorquí-Bagué, Núria (Hospital Universitari de Bellvitge)
Mestre-Bach, Gemma (Hospital Universitari de Bellvitge)
Lozano Madrid, María (Hospital Universitari de Bellvitge)
Fernández Aranda, Fernando (Hospital Universitari de Bellvitge)
Granero, Roser (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut)
Vintró Alcaraz, Cristina (Hospital Universitari de Bellvitge)
Del Pino Gutiérrez, Amparo (Hospital Universitari de Bellvitge)
Steward, Trevor (Hospital Universitari de Bellvitge)
Gomez-Peña, Monica (Hospital Universitari de Bellvitge)
Aymamí, Neus (Hospital Universitari de Bellvitge)
Mena Moreno, Teresa (Hospital Universitari de Bellvitge)
Menchón Magriñá, José Manuel (Hospital Universitari de Bellvitge)
Jiménez Murcia, Susana (Hospital Universitari de Bellvitge)
Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut

Data:	2018
Resum:	Gambling disorder (GD) is a highly heterogeneous condition with high rates of chronicity, relapses and treatment dropout. The aim of this study was to longitudinally explore the associations between trait impulsivity, impulsivity-compulsivity related cognitive domains, and treatment outcome in an outpatient sample of adult patients with GD. Methods: 144 adult male participants diagnosed with GD undergoing cognitive-behavioural treatment (CBT) at a specialized outpatient service completed a series of neuropsychological tests to assess executive functioning (including cognitive flexibility, inhibition control and decision making) and psychometric questionnaires. Results: Trait impulsivity predicted low compliance [UPPS-P negative urgency (B = 0. 113; p = 0. 019)] and relapse [UPPS-P negative urgency (B = 0. 140; p = 0. 015)] at 5 weeks of treatment and dropout at the end of treatment [(UPPS-P sensation seeking B = 0. 056; p = 0. 045)]. Cognitive flexibility performance predicted: dropout rates at the end of treatment [WCST perseverative errors (B = 0. 043; p = 0. 042)]; dropout [WCST categories completed (B = -1. 827; p = 0. 020)] and low compliance or relapses at follow-up [WCST perseverative errors (B = 0. 128; p = 0. 020)]; and time to first relapse [WCST failure to maintain set (B = -0. 374; p = 0. 048)] and time to dropout [WCST perseverative errors (B = 0. 0198; p = 0. 019)]. Conclusions: Our findings indicate impulsivity-compulsivity levels may influence response to GD treatment (i. e. : low compliance and dropout or relapse rates) thus representing a potential target for improving treatment outcomes.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Matèria:	Cognitive flexibility ; Compulsivity ; Gambling disorder ; Impulsivity ; Inhibitory control ; Treatment
Publicat a:	Addictive behaviors, Vol. 87 (2018) , p. 169-176, ISSN 1873-6327

DOI: 10.1016/j.addbeh.2018.07.006
PMID: 30048796

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