Headaches and facial pain attributed to SARS-CoV-2 infection and vaccination : a systematic review
Mitsikostas, Dimos (National & Kapodistrian University of Athens)
Caronna, Edoardo (Vall d'Hebron Institut de Recerca (VHIR))
De Tommaso, Marina (Università degli Studi di Bari Aldo Moro)
Deligianni, Christina I. (Athens Naval Hospital)
Ekizoglu, Esme (Istanbul University)
Bolay, Hayrunnisa (Gazi University Ankara)
Göbel, Carl Hartmut (Universitätsklinikum Schleswig-Holstein)
Kristoffersen, Espen Saxhaug (University of Oslo)
Lampl, Christian (Headache Medical Center Linz)
Moro, Elena (Grenoble Alpes University)
Pozo-Rosich, Patricia (Universitat Autònoma de Barcelona. Departament de Medicina)
Sellner, Johann (Landesklinikum Mistelbach-Gänserndorf)
Terwindt, Gisela (Leiden University Medical Center)
Irimia, Pablo (Clínica Universidad de Navarra)

Data:	2024
Resum:	The aim was to provide insights to the characteristics of headache in the context of COVID-19 on behalf of the Headache Scientific Panel and the Neuro-COVID-19 Task Force of the European Academy of Neurology (EAN) and the European Headache Federation (EHF). Following the Delphi method the Task Force identified six relevant questions and then conducted a systematic literature review to provide evidence-based answers and suggest specific diagnostic criteria. No data for facial pain were identified in the literature search. (1) Headache incidence during acute COVID-19 varies considerably, with higher prevalence rates in prospective compared to retrospective studies (28. 9%-74. 6% vs. 6. 5%-34. 0%). (2) Acute COVID-19 headache is usually bilateral or holocranial and often moderate to severe with throbbing pain quality lasting 2-14 days after first signs of COVID-19; photo-phonophobia, nausea, anosmia and ageusia are common associated features; persistent headache shares similar clinical characteristics. (3) Acute COVID-19 headache is presumably caused by immune-mediated mechanisms that activate the trigeminovascular system. (4) Headache occurs in 13. 3%-76. 9% following SARS-CoV-2 vaccination and occurs more often amongst women with a pre-existing primary headache; the risk of developing headache is higher with the adenoviral-vector-type vaccines than with other preparations. (5) Headache related to SARS-CoV-2 vaccination is mostly bilateral, and throbbing, pressing, jolting or stabbing. (6) No studies have been conducted investigating the underlying mechanism of headache attributed to SARS-CoV-2 vaccines. The results of this joint EAN/EHF initiative provide a framework for a better understanding of headache in the context of SARS-CoV-2 infection and vaccination.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Chronic daily headache ; Headache ; Neurological disorders
Publicat a:	European Journal of Neurology, Vol. 31 Núm. 6 (February 2024) , ISSN 1468-1331

DOI: 10.1111/ene.16251
PMID: 38415282

13 p, 786.3 KB

El registre apareix a les col·leccions:
Articles > Articles de recerca
Articles > Articles publicats