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| Pàgina inicial > Articles > Articles publicats > ENIGMA-Chronic Pain : |
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| Pàgina inicial > Articles > Articles publicats > ENIGMA-Chronic Pain : |
(University of New South Wales) (University of Southern California) (Heidelberg University. Department of Psychiatry and Psychotherapy) (University of Dundee) (Northwestern University Feinberg School of Medicine) (University of Colorado. Department of General Internal Medicine) (Medical University of South Carolina. Department of Psychiatry and Behavioral Sciences) (Duke University) (University of Oxford. Department of Paediatrics) (University of California. Department of Psychiatry) (Medical University of South Carolina. Department of Psychiatry and Behavioral Sciences) (Aalborg Universitet. Institut for Medicin og Sundhedsteknologi) (University of Edinburgh. Department of Psychology) (University of Florida. Pain Research and Intervention Center of Excellence) (Universität Münster. Institut für Translationale Psychiatrie) (Aalborg Universitet. Institut for Medicin og Sundhedsteknologi) (Università degli studi di Bari Aldo Moro. Dipartimento di Biomedicina Traslazionale e Neuroscienze) (Hospital del Mar (Barcelona, Catalunya)) (Universitätsmedizin Greifswald) (University of Melbourne) (University of Sydney) (Massachusetts General Hospital (Boston)) (University Hospital of Clermont-Ferrand) (Heidelberg University. Institute of Cognitive and Clinical Neuroscience) (University of California San Diego. Department of Psychiatry) (University of New South Wales) (Karolinska Institutet. Department of Clinical Science) (Massachusetts General Hospital (Boston)) (Massachusetts General Hospital (Boston)) (University of Miami. Department of Radiology) (Aalborg Universitet. Institut for Medicin og Sundhedsteknologi) (Karolinska Institutet. Department of Clinical Science) (University of Dundee) (Duke Univeristy) (University Medical Center Schleswig-Holstein. Institute of Medical Psychology and Medical Sociology) (Chinese Academy of Sciences) (Karolinska Institutet. Department of Clinical Neuroscience) (University of Marburg. Department of Psychiatry and Psychotherapy) (University of California. Department of Psychiatry) (Universität Münster. Institut für Translationale Psychiatrie) (Johns Hopkins University. Department of Biostatistics) (Massachusetts General Hospital (Boston)) (Universitätsmedizin Greifswald) (Duke University. Department of Anesthesiology) (Morgan State University. Department of Biology) (Universität Münster. Institut für Translationale Psychiatrie) (Aalborg Universitet. Institut for Medicin og Sundhedsteknologi) (Duke University) (University of Colorado. Department of General Internal Medicine) (University Medical Center Schleswig-Holstein. Institute of Medical Psychology and Medical Sociology) (University of Marburg. Department of Psychiatry and Psychotherapy) (University of New South Wales) (Medical University of South Carolina. Department of Psychiatry and Behavioral Sciences) (Technische Universität München. Abteilung für Neurologie) (Hospital del Mar (Barcelona, Catalunya)) (University of Miami. Department of Neurological Surgery) (University of Miami. Department of Radiology) (University of Western Ontario) (Heidelberg University. Institute of Cognitive and Clinical Neuroscience) (University of Oxford. Department of Paediatrics) (University of Marburg. Department of Psychiatry and Psychotherapy) (Emory University. Department of Psychiatry and Behavioral Sciences) (Universitätsmedizin Greifswald. Abteilung für Neurologie) (Duke University) (McGill University) (University of Florida. Department of Community Dentistry and Behavioral Sciences) (Trinity College Dublin. Global Brain Health Institute) (UCL Great Ormond Street Institute of Child Health. Department of Anaesthesia and Pain Medicine) (Dartmouth College) (University of Miami. Department of Neurological Surgery) (Atlanta Veterans Affairs Healthcare System) (University of California San Diego. Department of Anesthesiology) (University of Southern California. Imaging Genetics Center) (University of Southern California. Imaging Genetics Center) (University of Southern California. Imaging Genetics Center) (University of Southern California. Imaging Genetics Center) (University of Southern California. Imaging Genetics Center) (University of New South Wales)| Títol variant: | Enhancing Neuroimaging and Genetics through Meta-Analysis-Chronic Pain |
| Data: | 2024 |
| Descripció: | 5 pàg. |
| Resum: | Chronic pain has a profound societal burden, affecting 20% to 30% of the world population, and is associated with high rates of comorbid mental health conditions, especially depression and anxiety. Women and people of increasing age are disproportionately affected by chronic pain, and while there are pharmacological and nonpharmacological treatments available, many individuals still do not benefit from these treatments. One significant challenge in providing effective pain-relieving treatments arises from our incomplete understanding of the mechanisms underlying the development and maintenance of chronic pain. Some of these mechanisms include changes in brain morphology and function. One approach to better understand these mechanisms is to combine neuroimaging studies of diverse populations with the purpose of identifying common phenotypes and neuroimaging correlates. Phenotyping to explore both similarities and heterogeneity across pain conditions is necessary to inform disease prognosis and elucidate common treatment targets. To this endeavor, the Enhancing Neuroimaging and Genetics through Meta-Analysis (ENIGMA)-Chronic Pain working group was formed in November 2022. ENIGMA-Chronic Pain has since welcomed over 70 pain investigators from all over the world, to pool and integrate existing neuroimaging and clinical data from approximately 2000 chronic pain and 4000 pain-free healthy individuals, from over 30 international and independently collected datasets. |
| Ajuts: | European Commission 101087925 European Commission 101141285 |
| Nota: | Altres ajuts: The ENIGMA-Chronic Pain working group gratefully acknowledges support from the United States National Institutes of Health (NIH) Big Data to Knowledge (BD2K) award (U54EB020403 to P.M.T.). This work was supported by a Rebecca Cooper Fellowship from the Rebecca L. Cooper Medical Research Foundation, grants from the Deutsche Forschungsgemeinschaft (SFB1158/B03, SFB1158/B06, SFB1158/B07, SFB1158/S03N, FOR2107 DA1151/5-1, DA1151/5-2, DA1151/9-1, DA1151/101, DA1151/11-1, SFB-TRR58, Projects C09 and Z02, KI588/141, KI588/14-2, KI588/20-1, KI588/22-1, NE2254/1-2, NE2254/ 2-1, NE2254/3-1, NE2254/4-1), the Interdisciplinary Center for Clinical Research (IZKF) of the medical faculty of M¨unster (Dan3/ 022/22), a joint grant from the UK Biological and Biotechnology Research Council and the Economic and Social Research Council (BB/W008793/1), the UK Medical Research Council (MR/R024065/1, MR/W002566/1-Consortium Against Pain Inequality), Age UK ("The Disconnected Mind"), the Milton Damerel Trust and the University of Edinburgh, the National Science Foundation NSF GRFP (2020290241), Fonds Wetenschappelijk Onderzoek-FWO (G001419N), the Australian National Health And Medical Research Council (NHMRC Project Grant 1122816), and the US NIH (R01AG050595, R01AG076838, K01AG081559, NIDA R01DA055850, NINDS RM1NS128787). This work is partially funded by a Veterans Affairs Rehabilitation Research and Development award (RX00327) and Center Grant (RX002358). Research at GOSH NHSFoundation Trust and UCL Great OrmondStreet Institute of Child Health is supported by the NIHR GOSH Biomedical Research Centre.The Center for Neuroplasticity and Pain (CNAP) is supported by the Danish National Research Foundation (DNRF121). |
| Drets: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.  |
| Llengua: | Anglès |
| Document: | Article ; recerca ; Versió publicada |
| Matèria: | ENIGMA ; Chronic pain ; Comorbid mental health ; Neuroimaging data ; Working group |
| Publicat a: | Pain, Vol. 165, Núm. 12 (December 2024) , p. 2662-2666, ISSN 1872-6623 |
