Sex-based differences in jumping to conclusions : a multidimensional analysis of first-episode psychosis
Díaz-Cutraro, Luciana (Institut de Recerca Sant Joan de Déu)
Verdaguer-Rodríguez, Marina (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
García-Mieres, Helena (Universitat Oberta de Catalunya)
Ferrer-Quintero, Marta (Hospital General Universitario Gregorio Marañón)
López-Carrilero, Raquel (Parc Sanitari Sant Joan de Déu)
Palma-Sevillano, Carolina (Universitat Ramon Llull)
Lamarca, Maria (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
Espinosa, Victoria (Institut de Recerca Sant Joan de Déu)
Barrigón, María Luisa (Consorcio de Investigación Biomédica en Red de Salud Mental)
González-Higueras, Fermín (Hospital Universitario de Jaén)
Pousa, Esther (Consorcio de Investigación Biomédica en Red de Salud Mental)
Grasa, Eva (Consorcio de Investigación Biomédica en Red de Salud Mental)
Lorente-Rovira, Ester (Consorcio de Investigación Biomédica en Red de Salud Mental)
Gutiérrez-Zotes, Alfonso (Consorcio de Investigación Biomédica en Red de Salud Mental)
Barajas Vélez, Ana (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
Ruiz-Delgado, Isabel (Hospital Regional Universitario de Málaga)
Cid Colom, Jordi (Institut d'Investigació Biomèdica de Girona)
Moritz, Steffen (University Medical Center Hamburg-Eppendorf. Department of Psychiatry and Psychotherapy)
Rico, Julia (Universitat Ramon Llull)
Sevilla-Llewellyn-Jones, Julia (Hospital Clínico San Carlos (Madrid))
Haro Abad, Josep Maria (Institut de Recerca Sant Joan de Déu)
Ochoa, Susana (Institut de Recerca Sant Joan de Déu)

Date:	2025
Description:	14 pàg.
Abstract:	Jumping to conclusions (JTC) bias is a hallmark cognitive bias in psychosis that involves hasty decision-making with limited evidence. Previous research has shown links between JTC and neurocognitive (NC), social cognitive (SC), metacognitive (MC), and clinical (CV) variables, but sex-based differences in these relationships remain understudied. This multicenter cross-sectional study included 121 first-episode psychosis (FEP) patients from nine Spanish mental health centers. Participants underwent comprehensive assessments of JTC, SC, NC, MC, and CV, and the interaction between JTC and sex was analysed. JTC-women attributed negative causes of events to themselves more often than non-JTC women and men, while JTC-men displayed more cognitive rigidity, slower processing speed, and better self-esteem compared to their non-JTC counterparts. Non-JTC-women showed better verbal memory recall. Logistic regression revealed distinct predictors for JTC by sex: women were influenced by negative internalization of events and visuospatial speed, while men's JTC was linked to errors in executive functions and memory. These results highlight the importance of sex-specific patterns in JTC and suggest that women might benefit from interventions targeting reflective thinking and social cognition, whereas men may need neurocognitive rehabilitation strategies.
Grants:	Agencia Estatal de Investigación PID2020-118907RA-I00 Ministerio de Ciencia e Innovación PI11/01347 Ministerio de Economía y Competitividad PI14/00044
Note:	Altres ajuts: L.D.-C. was a beneficiary of a Predoctoral Training Grant in Health Research in this project, research grant number FI19/00062 ("Ayudas para la contratación de personal predoctoral") by the Instituto de Salud Carlos III (Spanish Government). This work was supported by the Fondo Europeo de Desarrollo Regional (FEDER), Progress and Health Foundation of the Andalusian Regional Ministry of Health (grant PI-0634/ 2011 and PI-0193/2014), Obra Social La Caixa (RecerCaixa call 2013), Obra Social Sant Joan de Déu (BML).
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Psychiatric disorders ; Psychosis ; Schizophrenia
Published in:	Schizophrenia, Vol. 11 (April 2025) , art. e60, ISSN 2754-6993

DOI: 10.1038/s41537-025-00579-0
PMID: 40221473

14 p, 817.2 KB

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