Prenatal and Perinatal Factors Associated with Infant Acute Lymphoblastic Leukaemia : A Scoping Review
Sanvisens, Arantza (Descriptive Epidemiology, Genetics, and Cancer Prevention Group, Josep Carreras Leukaemia Research Institute, 17004 Girona, Spain)
Bueno, Clara (Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III (ISCIII), 08028 Barcelona, Spain)
Calvete, Oriol (Myelodysplastic Syndrome Group, Josep Carreras Leukaemia Research Institute, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain (F.S.))
Sole, F. (Myelodysplastic Syndrome Group, Josep Carreras Leukaemia Research Institute, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain (F.S.))
Marcos-Gragera, Rafael (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública)
Solans, Marta (Universitat de Girona. Grup de Recerca en Estadística, Econometria i Salut)

Fecha:	2025
Resumen:	This scoping review provides an overview of the few observational studies that have investigated potential risk factors for acute lymphoblastic leukaemia in infants. It summarises some well-established associations in the literature, such as maternal exposure to pesticides and high birth weight, and outlines suggestive associations, such as heavy parental smoking, parental use of multiple medications, and maternal exposure to air pollution during pregnancy, that merit further research. The results of this review highlight the lack of research on infant acute lymphoblastic leukaemia, which contrasts with the large number of epidemiological studies investigating risk factors in childhood. Objective: Acute lymphoblastic leukaemia (ALL) is the most frequent childhood cancer. Infant ALL (.
Ayudas:	Instituto de Salud Carlos III, Spanish Ministry of Economy and Competitiveness European Regional Development Fund, ERDF, a way to build Europe PI 20/00531 European Regional Development Fund, ERDF, a way to build Europe PI20/00822 European Regional Development Fund, ERDF, a way to build Europe PLE2021-007518 Asociación Española Contra el Cancer (AECC) PRYGN211192BUEN TRANSCAN AECC and ISCIII AC 18/000002 Generalitat de Catalunya with economical support from the CERCA Programme/Generalitat de Catalunya 2017 SGR288 (GRC) Generalitat de Catalunya with economical support from the CERCA Programme/Generalitat de Catalunya 2021 CSGR 00560 (GRC) Fundació Internacional Josep Carreras; Fundación UnoEntreCienmil 2021 CSGR 00560 (GRC)
Derechos:	Aquesta url de drets no existeix a la base de dades.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Acute lymphoblastic leukaemia ; Infant ; Prenatal exposure ; Parental exposure ; Risk factor
Publicado en:	Cancers, Vol. 17 (January 2025), art. 370, ISSN 2072-6694

DOI: 10.3390/cancers17030370

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