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873.
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None, 1.3 MB |
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee : a population-based cohort study
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Bayliss, Lee E. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford) ;
Culliford, David (NIHR CLAHRC Wessex Methodological Hub, University of Southampton, Southampton, UK) ;
Monk, A. Paul (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK) ;
Glyn-Jones, Sion (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Judge, Andrew (MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK) ;
Carr, Andrew J. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK) ;
Beard, David J. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK) ;
Price, Andrew J. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK)
Total joint replacements for end-stage osteoarthritis of the hip and knee are cost-effective and demonstrate significant clinical improvement. However, robust population based lifetime-risk data for implant revision are not available to aid patient decision making, which is a particular problem in young patient groups deciding on best-timing for surgery. [...]
2017 -  10.1016/S0140-6736(17)30059-4
The Lancet (British), Vol. 389 (april 2017) , p. 1424-1430
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874.
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23 p, 2.2 MB |
Discovery of a new family of relaxases in Firmicutes bacteria
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Gayetri Ramachandran, Andrés (Centro de Biología Molecular Severo Ochoa) ;
Miguel Arribas, Andrés (Centro de Biología Molecular Severo Ochoa) ;
Abia, David (Centro de Biología Molecular Severo Ochoa) ;
Singh, Praveen K. (Centro de Biología Molecular Severo Ochoa) ;
Crespo, Isidro (ALBA Laboratori de Llum de Sincrotró) ;
Gago-Córdoba, César (Centro de Biología Molecular Severo Ochoa) ;
Hao, Jian An (Centro de Biología Molecular Severo Ochoa) ;
Luque-Ortega, Juan Román (Centro de Investigaciones Biológicas (Madrid)) ;
Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ;
Wu, Ling J. (Newcastle University. Institute for Cell and Molecular Biosciences. Centre for Bacterial Cell Biology) ;
Boer, Roeland (ALBA Laboratori de Llum de Sincrotró) ;
Meijer, Wilfried J. J. (Centro de Biología Molecular Severo Ochoa)
Antibiotic resistance is a serious global problem. Antibiotic resistance genes (ARG), which are widespread in environmental bacteria, can be transferred to pathogenic bacteria via horizontal gene transfer (HGT). [...]
2017 - 10.1371/journal.pgen.1006586
PLoS Genetics, Vol. 13, issue 2 (Feb. 2017) , e1006586
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875.
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14 p, 1.1 MB |
Complex evolutionary history of the mammalian histone H1.1-H1.5 gene family
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Ponte Marull, Immaculada (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Romero, Devani (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Yero, Daniel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Suau León, Pere (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Roque Córdova, Alicia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
H1 is involved in chromatin higher-order structure and gene regulation. H1 has a tripartite structure. The central domain is stably folded in solution, while the N- and C-terminal domains are intrinsically disordered. [...]
2017 - 10.1093/molbev/msw241
Molecular biology and evolution, Vol. 34, issue 3 (March 2017) , p. 545-558
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876.
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17 p, 500.1 KB |
DnaSP 6 : DNA sequence polymorphism analysis of large data sets
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Rozas, Julio (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Ferrer-Mata, Albert (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Sánchez-DelBarrio, Juan Carlos (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Guirao-Rico, Sara (Centre de Recerca en Agrigenòmica) ;
Librado, Pablo (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Ramos-Onsins, Sebastian (Centre de Recerca en Agrigenòmica) ;
Sánchez-Gracia, Alejandro (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística)
We present version 6 of the DnaSP (DNA Sequence Polymorphism) software, a new version of the popular tool for performing exhaustive population genetic analyses on multiple sequence alignments. This major upgrade incorporates novel functionalities to analyse large datasets, such as those generated by high-throughput sequencing (HTS) technologies. [...]
2017 - 10.1093/molbev/msx248
Molecular biology and evolution, Vol. 34, issue 12 (Dec. 2017) p. 3299-3302
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877.
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18 p, 732.6 KB |
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
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Guadalupe, Tulio (International Max Planck Research School for Language Sciences (Nijmegen, Països Baixos)) ;
Mathias, Samuel R. ;
vanErp, Theo G. M. ;
Whelan, Christopher D. ;
Zwiers, Marcel P ;
Abe, Yoshinari ;
Abramovic, Lucija ;
Agartz, Ingrid ;
Andreassen, Ole A. ;
Arias-Vásquez, Alejandro ;
Aribisala, Benjamin S. ;
Armstrong, Nicola ;
Arolt, Volker ;
Artiges, Eric (University Paris Descartes -Sorbonne Paris Cité (París, França)) ;
Ayesa-Arriola, Rosa (Centro de Investigación Biomédica en Red de Salud Mental) ;
Baboyan, Vatche G. ;
Banaschewski, Tobias ;
Barker, Gareth ;
Bastin, Mark E. ;
Baune, Bernhard T. ;
Blangero, John ;
Bokde, Arun L. W. ;
Boedhoe, Premika (Neuroscience Campus Amsterdam, Amsterdam, The Netherlands) ;
Bose, Anushree ;
Brem, Silvia ;
Brodaty, Henry ;
Bromberg, Uli ;
Brooks, Samantha ;
Büchel, Christian ;
Buitelaar, Jan ;
Calhoun, Vince ;
Cannon, Dara M. ;
Cattrell, Anna ;
Cheng, Yuqi ;
Conrod, Patricia ;
Conzelmann, Annette ;
Corvin, Aiden ;
Crespo-Facorro, Benedicto (Centro de Investigación Biomédica en Red de Salud Mental) ;
Crivello, Fabrice ;
Dannlowski, Udo ;
de Zubicaray, Greig ;
De Zwarte, Sonja M. C. ;
Deary, Ian J. ;
Desrivières, Sylvane ;
Doan, Nhat Trung ;
Donohoe, Gary ;
Dørum, Erlend S. ;
Ehrlich, Stefan ;
Espeseth, Thomas ;
Fernández, Guillén (Raboud University, Nijmegen, The Netherlands) ;
Flor, Herta ;
Fouche, Jean-Paul ;
Frouin, Vincent ;
Fukunaga, Masaki ;
Gallinat, Jürgen ;
Garavan, Hugh P ;
Gill, Michael ;
Suarez, Andrea Gonzalez ;
Gowland, Penny ;
Grabe, Hans J. (HELIOS Hospital Stralsund (Stralsund, Alemanya)) ;
Grotegerd, Dominik ;
Gruber, Oliver ;
Hagenaars, Saskia ;
Hashimoto, Ryota ;
Hauser, Tobias U. (University College London) ;
Heinz, Andreas ;
Hibar, Derrek P. ;
Hoekstra, Pieter J. (University of Groningen. Department of Psychiatry) ;
Hoogman, Martine ;
Howells, Fleur M. ;
Hu, Hao ;
Hulshoff Pol, Hilleke E. ;
Huyser, Chaim ;
Ittermann, Bernd ;
Jahanshad, Neda ;
Jönsson, Erik G. ;
Jurk, Sarah ;
Kahn, Rene S. ;
Kelly, Sinead ;
Kraemer, Bernd ;
Kugel, Harald ;
Kwon, Jun Soo ;
Lemaitre, Herve (Institut National de la Santé et de la Recherche Médicale (Paris, França)) ;
Lesch, Klaus-Peter ;
Lochner, Christine (University of Stellenbosch. Department of Psychiatry) ;
Luciano, Michelle ;
Marquand, Andre F. ;
Martin, Nicholas G. ;
Martínez-Zalacaín, Ignacio (Hospital Universitari de Bellvitge) ;
Martinot, Jean-Luc ;
Mataix-Cols, David ;
Mather, Karen A ;
McDonald, Colm ;
McMahon, Katie L. ;
Medland, Sarah Elizabeth ;
Menchón Magriñá, José Manuel (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Morris, Derek W. ;
Mothersill, Omar ;
Maniega, Susana Munoz ;
Mwangi, Benson ;
Nakamae, Takashi ;
Nakao, Tomohiro ;
Narayanaswaamy, Janardhanan C. ;
Nees, Frauke ;
Nordvik, Jan E. ;
Onnink, A. Marten H. ;
Opel, Nils ;
Ophoff, Roel ;
Paillère Martinot, Marie-Laure ;
Papadopoulos Orfanos, Dimitri ;
Pauli, Paul ;
Paus, Tomáš ;
Poustka, Luise ;
Reddy, Janardhan YC. ;
Rentería, Miguel E. ;
Roiz-Santiáñez, Roberto (Centro de Investigación Biomédica en Red de Salud Mental) ;
Roos, Annerine (University of Stellenbosch. Department of Psychiatry) ;
Royle, Natalie A. ;
Sachdev, Perminder ;
Sánchez-Juan, Pascual (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Schmaal, Lianne ;
Schumann, Gunter ;
Shumskaya, Elena ;
Smolka, Michael N. ;
Soares, Jair C. ;
Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Stein, Dan J. (University of Cape Town. Department of Psychiatry) ;
Strike, Lachlan ;
Toro, Roberto ;
Turner, Jessica A. ;
Tzourio-Mazoyer, Nathalie ;
Uhlmann, Anne ;
Hernández, Maria Valdés ;
van den Heuvel, Odile A. (Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands) ;
van der Meer, Dennis (University of Groningen. Department of Psychiatry) ;
van Haren, Neeltje E. M. ;
Veltman, Dick J. ;
Venkatasubramanian, Ganesan ;
Vetter, Nora C. ;
Vuletic, Daniella ;
Walitza, Susanne ;
Walter, Henrik ;
Walton, Esther ;
Wang, Zhen ;
Wardlaw, Joanna ;
Wen, Wei ;
Westlye, Lars T. ;
Whelan, Robert ;
Wittfeld, Katharina (Site Rostock, Greifswald, Germany) ;
Wolfers, Thomas (Raboud University, Nijmegen, The Netherlands) ;
Wright, Margaret J. ;
Xu, Jian ;
Xu, Xiufeng ;
Yun, Je-Yeon ;
Zhao, JingJing ;
Franke, Barbara ;
Thompson, Paul M. ;
Glahn, David C. (Olin Neuropsychiatric Research Center (Estats Units)) ;
Mazoyer, Bernard ;
Fisher, Simon E. (Raboud University) ;
Francks, Clyde (Donders Institute for Brain, Cognition and Behaviour, Raboud University, Nijmegen, The Netherlands)
The online version of this article (doi:10. 1007/s11682-016-9629-z) contains supplementary material, which is available to authorized users.
2016 - 10.1007/s11682-016-9629-z
Brain Imaging and Behavior, Vol. 11 (october 2016) , p. 1497-1514
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878.
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12 p, 849.5 KB |
A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer's disease
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Verheijen, Jan (University of Antwerp. Institute Born-Bunge) ;
Van den Bossche, Tobi (University Hospital Antwerp (Bèlgica)) ;
van der Zee, Julie (University of Antwerp. Institute Born-Bunge) ;
Engelborghs, Sebastiaan (University Hospital Antwerp (Bèlgica)) ;
Sánchez Valle, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Llado Plarrumani, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Graff, Caroline (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Thonberg, Håkan (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Pastor, Pau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Ortega-Cubero, Sara (Complejo Asistencial Universitario de Palencia. Departamento de Neurología) ;
Pastor, Maria A. (Clínica Universidad de Navarra) ;
Benussi, Luisa (Istituto Centro San Giovanni di Dio-Fatebenefratelli (Brescia, Itàlia)) ;
Ghidoni, Roberta (Istituto Centro San Giovanni di Dio-Fatebenefratelli (Brescia, Itàlia)) ;
Binetti, Giuliano (Istituto Centro San Giovanni di Dio-Fatebenefratelli (Brescia, Itàlia)) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó Bisa, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
de Mendonça, Alexandre (University of Lisbon. Faculty of Medicine and Institute of Molecular Medicine) ;
Martins, Madalena (University of Lisbon. Faculty of Medicine and Institute of Molecular Medicine) ;
Grau-Rivera, Oriol (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gelpi, Ellen (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Bettens, Karolien (University of Antwerp. Institute Born-Bunge) ;
Mateiu, Ligia (University of Antwerp. VIB) ;
Dillen, Lubina (University of Antwerp. Institute Born-Bunge) ;
Cras, Patrick (University Hospital Antwerp (Bèlgica)) ;
De Deyn, Peter Paul (University Hospital Antwerp (Bèlgica)) ;
Van Broeckhoven, Christine (University of Antwerp. Institute Born-Bunge) ;
Sleegers, Kristel (University of Antwerp. Institute Born-Bunge) ;
Universitat Autònoma de Barcelona
The sortilin-related receptor 1 (SORL1) gene has been associated with increased risk for Alzheimer's disease (AD). Rare genetic variants in the SORL1 gene have also been implicated in autosomal dominant early-onset AD (EOAD). [...]
2016 - 10.1007/s00401-016-1566-9
Acta Neuropathologica, Vol. 132 (march 2016) , p. 213-224
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879.
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16 p, 1.3 MB |
Latitudinal Clines of the Human Vitamin D Receptor and Skin Color Genes
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Tiosano, Dov (Technion - Israel Institute of Technology. Rappaport Family Faculty of Medicine) ;
Audí, Laura (Hospital Universitari Vall d'Hebron) ;
Climer, Sharlee (Department of Computer Science and Engineering, Washington University) ;
Zhang, Weixiong (Department of Computer Science and Engineering) ;
Templeton, Alan R. (Department of Evolutionary and Environmental Biology, University of Haifa) ;
Fernández Cancio, Mónica (Hospital Universitari Vall d'Hebron) ;
Gershoni-Baruch, Ruth (Department of Evolutionary and Environmental Biology, University of Haifa) ;
Sánchez-Muro, José Miguel (Pediatric Service, Area Basica de Salut (ABS)) ;
El Kholy, Mohamed (Department of Pediatrics, Ain Shams University) ;
Hochberg, Zèev (Technion - Israel Institute of Technology. Rappaport Family Faculty of Medicine) ;
Universitat Autònoma de Barcelona
The well-documented latitudinal clines of genes affecting human skin color presumably arise from the need for protection from intense ultraviolet radiation (UVR) vs. the need to use UVR for vitamin D synthesis. [...]
2016 - 10.1534/g3.115.026773
G3, Vol. 6 (february 2016) , p. 1251-1266
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880.
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9 p, 730.3 KB |
Safety and Efficacy of Solitaire Stent Thrombectomy
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Campbell, Bruce C.V ;
Hill, M. D ;
Rubiera Del Fueyo, Marta A ;
Menon, Bijoy K. ;
Demchuk, Andrew ;
Donnan, Geoffrey A. ;
Roy, Daniel ;
Thornton, John ;
Dorado Bouix, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bonafe, Alain ;
Levy, Elad I. ;
Diener, Hans-Christoph ;
Hernández-Pérez, María ;
Pereira, Vitor Mendes ;
Blasco, Jordi ;
Quesada, Helena ;
Rempel, Jeremy ;
Jahan, Reza ;
Davis, Stephen M. ;
Stouch, Bruce C. ;
Mitchell, Peter J. ;
Jovin, Tudor G. ;
Saver, Jeffrey L.. ;
Goyal, Mayank ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is available in the text. Patient-level data were pooled from trials in which the Solitaire was the only or the predominant device used in a prespecified meta-analysis (SEER Collaboration): Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment (SWIFT PRIME), Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times (ESCAPE), Extending the Time for Thrombolysis in Emergency Neurological Deficits-Intra-Arterial (EXTEND-IA), and Randomized Trial of Revascularization With Solitaire FR Device Versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting Within Eight Hours of Symptom Onset (REVASCAT). [...]
2016 - 10.1161/STROKEAHA.115.012360
Stroke, Vol. 47 (february 2016) , p. 798-806
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881.
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882.
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30 p, 277.7 KB |
La medición de la estructura socio-ocupacional a partir de lógicas deductivas e inductivas. Estudio para el caso del Aglomerado Gran Buenos Aires (Argentina)
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Fernández Melián, María Clara (Universidad de Buenos Aires)
La posición de los individuos en la estructura socio-ocupacional ha sido frecuentemente utilizada para dar cuenta de otras problemáticas sociales esenciales como los diferenciales en las condiciones de vida, la movilidad social e incluso las opiniones políticas pero requiere, previamente, ser tratada ella misma como objeto de investigación El presente artículo se propone contribuir al debate en torno a la medición de la estructura socio-ocupacional poniendo en diálogo dos formas de abordaje y clasificación social: por un lado, a partir de una propuesta de clasificación basada en la perspectiva teórico-metodológica de Susana Torrado considerada clásica en los estudios sobre este campo; y, por otro lado, mediante la exploración de los datos ocupacionales y la construcción de agrupamientos a partir de variables consideradas teóricamente pertinentes y utilizando técnicas de análisis multivariado. [...]
The position of individuals in the socio-occupational structure has frequently been used to account for other essential social problems as the differentials in líving conditions, the social mobility and even the political opinions, but it may first, be treated as an object of research. [...]
2017
Encrucijadas. Revista Crítica de Ciencias Sociales, Vol. 14 (2017)
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