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15 p, 2.0 MB Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC / Ji, Xinyu (Nanjing Medical University) ; Lin, Lijuan (Nanjing Medical University) ; Fan, Juanjuan (Nanjing Medical University) ; Li, Yi (University of Michigan) ; Wei, Yongyue (Nanjing Medical University) ; Shen, Sipeng (Nanjing Medical University) ; Su, Li (Harvard T.H. Chan School of Public Health (Estats Units d'Amèrica)) ; Shafer, Andrea (Harvard Medical School) ; Bjaanæs, Maria Moksnes (Oslo University Hospital (Oslo, Noruega)) ; Karlsson, Anna (Lund University) ; Planck, Maria (Lund University) ; Staaf, Johan (Lund University) ; Helland, Åslaug (University of Oslo) ; Esteller, M (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zhang, Ruyang (Nanjing Medical University) ; Chen, Feng (Nanjing Medical University) ; Christiani, David C (Harvard Medical School) ; Universitat Autònoma de Barcelona
The interaction between DNA methylation of tripartite motif containing 27 (cg05293407) and smoking has previously been identified to reveal histologically heterogeneous effects of TRIM27 DNA methylation on early-stage non-small-cell lung cancer (NSCLC) survival. [...]
2022 - 10.1002/1878-0261.13167
Molecular Oncology, Vol. 16 Núm. 3 (february 2022) , p. 717-731  
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2.
17 p, 1.3 MB The transcribed ultraconserved region uc.160+ enhances processing and A-to-I editing of the miR-376 cluster : hypermethylation improves glioma prognosis / Soler, Marta (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sánchez Castillo, Anaís (Maastricht University Medical Center) ; Mora Martínez, Carlos (University of Helsinki) ; Setién, Fernando (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Siqueira, E (Conselho Nacional de Desenvolvimento Cientifico e Tecnológico) ; Castro de Moura, Manuel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Guil, Sonia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Transcribed ultraconserved regions (T-UCRs) are noncoding RNAs derived from DNA sequences that are entirely conserved across species. Their expression is altered in many tumor types, and, although a role for T-UCRs as regulators of gene expression has been proposed, their functions remain largely unknown. [...]
2022 - 10.1002/1878-0261.13121
Molecular Oncology, Vol. 16 Núm. 3 (february 2022) , p. 648-664  
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