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Published articles 4 records found  Search took 0.01 seconds. 
1.
11 p, 1.8 MB First insights into the pleiotropic role of vrf (yedF), a newly characterized gene of Salmonella Typhimurium / Ballesté-Delpierre, Clara (Barcelona Institute for Global Health (ISGlobal)) ; Fernandez-Orth, Dietmar (Centre de Recerca en Epidemiologia Ambiental) ; Ferrer-Navarro, Mario (Barcelona Institute for Global Health (ISGlobal)) ; Díaz-Peña, Ramón (Parc Científic de Barcelona) ; Odena-Caballol, Antonia (Parc Científic de Barcelona) ; Oliveira, Eliandre (Parc Científic de Barcelona) ; Fàbrega-Santamaria, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vila Estapé, Jordi (Barcelona Institute for Global Health (ISGlobal)) ; Universitat Autònoma de Barcelona
Salmonella possesses virulence determinants that allow replication under extreme conditions and invasion of host cells, causing disease. Here, we examined four putative genes predicted to encode membrane proteins (ydiY, ybdJ, STM1441 and ynaJ) and a putative transcriptional factor (yedF). [...]
2017 - 10.1038/s41598-017-15369-7
Scientific reports, Vol. 7 (november 2017)  
Detailed record - Creative Commons
2.
11 p, 1.8 MB A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses / Burgueño, Javier (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ; Pujol Argemí, Marta (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ; Monroy, Xavier (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ; Roche, David (Universitat Internacional de Catalunya. Facultat de Ciències Econòmiques i Socials) ; Varela, Maria Jose (Universidade de Santiago de Compostela) ; Merlos, Manuel (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública
Compelling data in the literature from the recent years leave no doubt about the pluridimensional nature of G protein-coupled receptor function and the fact that some ligands can couple with different efficacies to the multiple pathways that a receptor can signal through, a phenomenon most commonly known as functional selectivity or biased agonism. [...]
2017 - 10.1038/s41598-017-15258-z
Scientific reports, Vol. 7 (november 2017)  
Detailed record - Creative Commons
3.
13 p, 2.0 MB Kidney Androgen-Regulated Protein (KAP) Transgenic Mice Are Protected Against High-Fat Diet Induced Metabolic Syndrome / de Quixano, Beatriz Bardaji (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Villena, Josep A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Aranda Martín, Miguel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Brils, Gemma (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cuevas Alcalá, Antoni, (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hespel, Théana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lekuona, Haizea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Suárez, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tornavaca, Olga (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Meseguer Navarro, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Metabolic Syndrome (MS) is reaching epidemic proportions with significant social and economical burden worldwide. Since the molecular basis of MS remains poorly defined, we investigated the impact of KAP, a kidney specific androgen-regulated gene, in the development of high fat-diet (hfd)-induced MS. [...]
2017 - 10.1038/s41598-017-16487-y
Scientific reports, Vol. 7 (november 2017)  
Detailed record - Creative Commons
4.
12 p, 1.4 MB Consistency and flexibility in solving spatial tasks : different horses show different cognitive styles / Baragli, Paolo (University of Pisa. Museum of Natural History) ; Vitale, Valentina (Universitat Autònoma de Barcelona. Fundació Hospital Clínic Veterinari) ; Sighieri, Claudio (University of Pisa. Department of Veterinary Sciences) ; Lanata, Antonio (University of Pisa. Department of Information Engineering & Research Center "E. Piaggio") ; Palagi, Elisabetta (Institute of Cognitive Sciences and Technologies) ; Reddon, Adam R. (Liverpool John Moores University. School of Natural Sciences and Psychology)
Individual animals vary in their behaviour and reactions to novel situations. These differences may extend to differences in cognition among individuals. We tested twenty-six horses for their ability to detour around symmetric and asymmetric obstacles. [...]
2017 - 10.1038/s41598-017-16729-z
Scientific reports, Vol. 7 (november 2017)  
Detailed record - Creative Commons

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