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22 p, 4.6 MB Computational Drug Design Applied to the Study of Metabotropic Glutamate Receptors / Llinas del Torrent, Claudia (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Pérez-Benito, Laura (Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V., Belgium) ; Tresadern, Gary (Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V., Belgium)
Metabotropic glutamate (mGlu) receptors are a family of eight GPCRs that are attractive drug discovery targets to modulate glutamate action and response. Here we review the application of computational methods to the study of this family of receptors. [...]
2019 - 10.3390/molecules24061098
Molecules, Vol. 24 (march 2019)  
Detailed record - Creative Commons

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