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33 p, 2.5 MB UP-DOWN cortical dynamics reflect state transitions in a bistable network / Jercog, Daniel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Roxin, Alex (Centre de Recerca Matemàtica) ; Barthó, Peter (MTA TTK NAP B. Research Group of Sleep Oscillations) ; Luczak, Artur (University of Lethbridge. Canadian Center for Behavioural Neuroscience) ; Compte, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; de la Rocha, Jaime (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
In the idling brain, neuronal circuits transition between periods of sustained firing (UP state) and quiescence (DOWN state), a pattern the mechanisms of which remain unclear. Here we analyzed spontaneous cortical population activity from anesthetized rats and found that UP and DOWN durations were highly variable and that population rates showed no significant decay during UP periods. [...]
2017 - 10.7554/eLife.22425
eLife, Vol. 6 (August 2017) , art. e22425  

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