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18 p, 17.4 MB Bone Marrow Stromal Cell Regeneration Profile in Treated B-Cell Precursor Acute Lymphoblastic Leukemia Patients : Association with MRD Status and Patient Outcome / Oliveira, Elen (Federal University of Rio de Janeiro) ; Costa, Elaine S. (Federal University of Rio de Janeiro) ; Ciudad Pizarro, Juana (Universidad de Salamanca. Departamento de Medicina) ; Gaipa, Giuseppe (Department of Pediatrics. University of Milano-Bicocca) ; Sedek, Łukasz (Department of Microbiology and Immunology. Medical University of Silesia in Katowice) ; Barrena, Susana (Universidad de Salamanca. Departamento de Medicina) ; Szczepanski, Tomasz (Department of Pediatric Hematology and Oncology. Medical University of Silesia in Katowice) ; Buracchi, Chiara (Department of Pediatrics. University of Milano-Bicocca) ; Silvestri, Daniela (Department of Health Science. University of Milano-Bicocca) ; Siqueira, Patricia F.R. (Federal University of Rio de Janeiro) ; Mello, Fabiana V. (Instituto de Puericultura e Pediatria Martagão Gesteira (IPPMG). Faculty of Medicine. Federal University of Rio de Janeiro) ; Torres, Rafael C. (Federal University of Rio de Janeiro) ; Oliveira, Leonardo M.R. (Federal University of Rio de Janeiro) ; Fay-Neves, Isabelle V.C. (Federal University of Rio de Janeiro) ; Sonneveld, Edwin (Princess Maxima Center for Pediatric Oncology) ; Van der Velden, Vincent (University Medical Center Rotterdam) ; Mejstrikova, Esther (Childhood Leukaemia Investigation Prague) ; Ribera, Jose-Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Conter, Valentino (Department of Pediatrics. University of Milano-Bicocca) ; Schrappe, Martin (Universitätsklinikum Schleswig-Holstein (Alemanya)) ; van Dongen, Jacques J.M. (Department of Immunohematology and Blood Transfusion. Leiden University Medical Center) ; Land, Marcelo G.P. (Federal University of Rio de Janeiro) ; Orfao, Alberto (Universidad de Salamanca. Departament de Medicina) ; Universitat Autònoma de Barcelona
For the last two decades, measurable residual disease (MRD) has become one of the most powerful independent prognostic factors in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However, the effect of therapy on the bone marrow (BM) microenvironment and its potential relationship with the MRD status and disease free survival (DFS) still remain to be investigated. [...]
2022 - 10.3390/cancers14133088
Cancers, Vol. 14 Núm. 13 (7-1 2022) , p. 3088  
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