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Resultats globals: 2 registres trobats en 0.02 segons.
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Articles 2 registres trobats  
1.
18 p, 1.7 MB Essential Control of the Function of the Striatopallidal Neuron by Pre-coupled Complexes of Adenosine A-Dopamine D Receptor Heterotetramers and Adenylyl Cyclase / Ferré, Sergi (National Institutes of Health, Baltimore, United States) ; Bonaventura, Jordi (National Institutes of Health, Baltimore, United States) ; Zhu, Wendy (Circuit Therapeutics, Menlo Park, United States) ; Hatcher-Solis, Candice (National Institutes of Health, Baltimore, United States) ; Taura, Jaume (Universitat de Barcelona. Institut de Neurociències) ; Quiroz, César (National Institutes of Health, Baltimore, United States) ; Cai, Ning-Sheng (National Institutes of Health, Baltimore, United States) ; Moreno, Estefanía (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Casadó-Anguera, Verònica (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Kravitz, Alexxai V. (National Institutes of Health, Bethesda, United States) ; Thompson, Kimberly R. (Circuit Therapeutics, Inc., Menlo Park, United States) ; Tomasi, Dardo G. (National Institutes of Health, Rockville, United States) ; Navarro Brugal, Gemma (Universitat de Barcelona. Departament de Bioquímica i Fisiologia) ; Cordomí Montoya, Arnau (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Pardo Carrasco, Leonardo (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Lluís, Carme (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Dessauer, Carmen W. (University of Texas Health Science Center at Houston, United States) ; Volkow, Nora D. (National Institutes of Health, Rockville, United States) ; Casadó, Vicent (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Ciruela, Francisco (Universitat de Barcelona. Institut de Neurociències) ; Logothetis, Diomedes E. (Northeastern University, Boston, United States) ; Zwilling, Daniel (Circuit Therapeutics, Inc, Menlo Park, United States)
The central adenosine system and adenosine receptors play a fundamental role in the modulation of dopaminergic neurotransmission. This is mostly achieved by the strategic co-localization of different adenosine and dopamine receptor subtypes in the two populations of striatal efferent neurons, striatonigral and striatopallidal, that give rise to the direct and indirect striatal efferent pathways, respectively. [...]
2018 - 10.3389/fphar.2018.00243
Frontiers in Pharmacology, Vol. 9 (april 2018)  
Registre complet - Creative Commons
2.
12 p, 2.5 MB Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase / Navarro Brugal, Gemma (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Cordomí Montoya, Arnau (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Casadó-Anguera, Verònica (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Moreno, Estefanía (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Cai, Ning-Sheng (National Institutes of Health. Integrative Neurobiology Section, National Institute on Drug Abuse, USA) ; Cortés, Antoni (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Canela, Enric I. (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Dessauer, Carmen W. (University of Texas Health Science Center, USA) ; Casadó, Vicent (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Pardo Carrasco, Leonardo (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Lluís, Carme (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Ferré, Sergi (National Institutes of Health. Integrative Neurobiology Section, National Institute on Drug Abuse)
G protein-coupled receptors (GPCRs), G proteins and adenylyl cyclase (AC) comprise one of the most studied transmembrane cell signaling pathways. However, it is unknown whether the ligand-dependent interactions between these signaling molecules are based on random collisions or the rearrangement of pre-coupled elements in a macromolecular complex. [...]
2018 - 10.1038/s41467-018-03522-3
Nature communications, Vol. 9 (march 2018)  
Registre complet - Creative Commons

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