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Kappa free light chains is a valid tool in the diagnostics of MS : A large multicenter study
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Leurs, C. E. (VU University Medical Center. Department of Neurology) ;
Twaalfhoven, Ham (Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry) ;
Lissenberg-Witte, B. I. (Department of Epidemiology and Biostatistics, Amsterdam UMC) ;
van Pesch, V (Department of Neurology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain) ;
Dujmovic, Irena (Clinic of Neurology, Clinical Centre of Serbia, School of Medicine, University of Belgrade) ;
Drulovic, Jelena (Clinic of Neurology, Clinical Centre of Serbia, School of Medicine, University of Belgrade) ;
Castellazzi, M. (Department of Biomedical and Specialty Surgical Sciences, University of Ferrara) ;
Bellini, T. (Department of Biomedical and Specialty Surgical Sciences, University of Ferrara) ;
Pugliatti, M. (Department of Biomedical and Specialty Surgical Sciences, University of Ferrara) ;
Kuhle, Jens (Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research and Biomedicine, University Hospital Basel) ;
Villar, L. M. (Hospital Ramón y Cajal. Departamento de Inmunologia) ;
Alvarez-Cermeño, José C (Hospital Ramón y Cajal. Departamento de Neurologia) ;
Alvarez-Lafuente, Roberto (Instituto de Investigación Sanitaria San Carlos) ;
Hegen, Harald (Department of Neurology, Medical University of Innsbruck) ;
Deisenhammer, Florian (Department of Neurology, Medical University of Innsbruck) ;
Walchhofer, L. M. (Department of Neurology, Medical University of Innsbruck) ;
Thouvenot, Eric (Hôpital Caremeau, Nîmes. Departement of Neurology) ;
Comabella, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vécsei, L. (Department of Neurology, University of Szeged) ;
Rajda, C. (Department of Neurology, University of Szeged) ;
Galimberti, Daniela (Multiple Sclerosis Centre, University of Milan) ;
Scarpini, E. (Multiple Sclerosis Centre, University of Milan) ;
Altintas, Ayse (Koc University, School of Medicine, Neurology Department) ;
Rejdak, K. (Department of Neurology, Medical University of Lublin) ;
Frederiksen, J. L. (Department of Neurology, Rigshospitalet Glostrup and University of Copenhagen) ;
Pihl-Jensen, G. (Department of Neurology, Rigshospitalet Glostrup and University of Copenhagen) ;
Jensen, Peh (Danish Multiple Sclerosis Centre, Department of Neurology, Rigshospitalet, University of Copenhagen) ;
Khalil, Michael (Department of Neurology, Medical University of Graz) ;
Voortman, Margarete (Department of Neurology, Medical University of Graz) ;
Fazekas, F. (Department of Neurology, Medical University of Graz) ;
Saiz, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
La Puma, D. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Vercammen, M. (Department of Laboratory Medicine, AZ Sint-Jan Brugge-Oostende) ;
Vanopdenbosch, L. (Department of Neurology, AZ Sint-Jan Brugge-Oostende) ;
Uitdehaag, BMJ (Department of Neurology, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC) ;
Killestein, Joep (Department of Neurology, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC) ;
Bridel, C. (Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry) ;
Teunissen, Charlotte E. (Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
To validate kappa free light chain (KFLC) and lambda free light chain (LFLC) indices as a diagnostic biomarker in multiple sclerosis (MS). We performed a multicenter study including 745 patients from 18 centers (219 controls and 526 clinically isolated syndrome (CIS)/MS patients) with a known oligoclonal IgG band (OCB) status. [...]
2019 -  10.1177/1352458519845844
Multiple sclerosis, Vol. 26 (may 2019) , p. 912-923
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Consensus guidelines for lumbar puncture in patients with neurological diseases
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Engelborghs, Sebastiaan (University Hospital Antwerp (Bèlgica)) ;
Niemantsverdriet, Ellis (Reference Center for Biological Markers of Dementia (BIODEM), Department of Biomedical Sciences, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium) ;
Struyfs, Hanne (Reference Center for Biological Markers of Dementia (BIODEM), Department of Biomedical Sciences, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium) ;
Blennow, Kaj (Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden) ;
Brouns, Raf (Department of Neurology, Universitair Ziekenhuis Brussel (UZ Brussel), Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium) ;
Comabella, Manuel (Hospital Universitari Vall d'Hebron) ;
Dujmovic, Irena (Clinic of Neurology, Clinical Centre of Serbia, Department of Neurology, Faculty of Medicine, University of Belgrade School of Medicine, Belgrade, Serbia) ;
van der Flier, Wiesje (Amsterdam UMC. University Medical Center) ;
Frölich, Lutz (Central Institute of Mental Health (Manheim, Alemanya)) ;
Galimberti, Daniela (Neurology Unit, Department of Pathophysiology and Transplantation, University of Milan, Fondazione Ca' Granda, IRCCS Ospedale Policlinico, Milan, Italy) ;
Gnanapavan, Sharmilee (Queen Mary University of London) ;
Hemmer, Bernhard (Munich Cluster for Systems Neurology (SyNergy), Munich, Germany) ;
Hoff, Erik (Department of Neurology, Atrium Medisch Centrum Parkstad, Heerlen, The Netherlands) ;
Hort, Jakub (International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic) ;
Iacobaeus, Ellen (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Ingelsson, Martin (Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden) ;
Jan de Jong, Frank (Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands) ;
Jonsson, Michael (Sahlgrenska University Hospital (Suècia)) ;
Khalil, Michael (Department of Neurology, Medical University Graz, Graz, Austria) ;
Kuhle, Jens (University Hospital Basel (Basilea, Suïssa)) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
de Mendonça, Alexandre (Laboratory of Neurosciences, Department of Molecular Medicine and Faculty of Medicine, University of Lisbon, Lisbon, Portugal) ;
Molinuevo, José Luis (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Nagels, Guy (National MS Center Melsbroek, Brussels, Belgium) ;
Paquet, Claire (Research Memory Center Lariboisière Hospital University Paris Diderot INSERMU942, Paris, France) ;
Parnetti, Lucilla (Section of Neurology, Centre for Memory Disturbances, Department of Medicine, University of Perugia, Perugia, Italy) ;
Roks, Gerwin (Department of Neurology, St Elisabeth Ziekenhuis, Tilburg, The Netherlands) ;
Rosa-Neto, Pedro (Departments of Psychiatry, McGill Centre for Studies in Aging, Douglas Hospital Research Center, McGill University, Montreal, Canada) ;
Scheltens, Philip (Amsterdam UMC. University Medical Center) ;
Skårsgard, Constance (Department of Geriatrics, Kalmar County Hospital, Kalmar, Sweden) ;
Stomrud, Erik (Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden) ;
Tumani, Hayrettin (CSF Laboratory and Multiple Sclerosis Outpatient Unit, Department of Neurology, University of Ulm, Ulm, Germany) ;
Visser, Pieter Jelle (Maastricht University. Department of Psychiatry and Neuropsychology) ;
Wallin, Anders (Sahlgrenska University Hospital (Suècia)) ;
Winblad, Bengt (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ;
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ;
Duits, Flora (Amsterdam UMC. University Medical Center) ;
Teunissen, Charlotte E. (Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands) ;
Universitat Autònoma de Barcelona
Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the diagnostic workup of several neurological brain diseases. Reluctance to perform the procedure is among others due to a lack of standards and guidelines to minimize the risk of complications, such as post-LP headache or back pain. [...]
2017 - 10.1016/j.dadm.2017.04.007
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 8 (may 2017) , p. 111-126
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