Consensus guidelines for lumbar puncture in patients with neurological diseases
Engelborghs, Sebastiaan (University Hospital Antwerp (Bèlgica))
Niemantsverdriet, Ellis (Reference Center for Biological Markers of Dementia (BIODEM), Department of Biomedical Sciences, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium)
Struyfs, Hanne (Reference Center for Biological Markers of Dementia (BIODEM), Department of Biomedical Sciences, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium)
Blennow, Kaj (Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden)
Brouns, Raf (Department of Neurology, Universitair Ziekenhuis Brussel (UZ Brussel), Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium)
Comabella, Manuel (Hospital Universitari Vall d'Hebron)
Dujmovic, Irena (Clinic of Neurology, Clinical Centre of Serbia, Department of Neurology, Faculty of Medicine, University of Belgrade School of Medicine, Belgrade, Serbia)
van der Flier, Wiesje (Amsterdam UMC. University Medical Center)
Frölich, Lutz (Central Institute of Mental Health (Manheim, Alemanya))
Galimberti, Daniela (Neurology Unit, Department of Pathophysiology and Transplantation, University of Milan, Fondazione Ca' Granda, IRCCS Ospedale Policlinico, Milan, Italy)
Gnanapavan, Sharmilee (Queen Mary University of London)
Hemmer, Bernhard (Munich Cluster for Systems Neurology (SyNergy), Munich, Germany)
Hoff, Erik (Department of Neurology, Atrium Medisch Centrum Parkstad, Heerlen, The Netherlands)
Hort, Jakub (International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic)
Iacobaeus, Ellen (Karolinska University Hospital and Karolinska Institutet (Suècia))
Ingelsson, Martin (Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden)
Jan de Jong, Frank (Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands)
Jonsson, Michael (Sahlgrenska University Hospital (Suècia))
Khalil, Michael (Department of Neurology, Medical University Graz, Graz, Austria)
Kuhle, Jens (University Hospital Basel (Basilea, Suïssa))
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau)
de Mendonça, Alexandre (Laboratory of Neurosciences, Department of Molecular Medicine and Faculty of Medicine, University of Lisbon, Lisbon, Portugal)
Molinuevo, José Luis (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Nagels, Guy (National MS Center Melsbroek, Brussels, Belgium)
Paquet, Claire (Research Memory Center Lariboisière Hospital University Paris Diderot INSERMU942, Paris, France)
Parnetti, Lucilla (Section of Neurology, Centre for Memory Disturbances, Department of Medicine, University of Perugia, Perugia, Italy)
Roks, Gerwin (Department of Neurology, St Elisabeth Ziekenhuis, Tilburg, The Netherlands)
Rosa-Neto, Pedro (Departments of Psychiatry, McGill Centre for Studies in Aging, Douglas Hospital Research Center, McGill University, Montreal, Canada)
Scheltens, Philip (Amsterdam UMC. University Medical Center)
Skårsgard, Constance (Department of Geriatrics, Kalmar County Hospital, Kalmar, Sweden)
Stomrud, Erik (Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden)
Tumani, Hayrettin (CSF Laboratory and Multiple Sclerosis Outpatient Unit, Department of Neurology, University of Ulm, Ulm, Germany)
Visser, Pieter Jelle (Maastricht University. Department of Psychiatry and Neuropsychology)
Wallin, Anders (Sahlgrenska University Hospital (Suècia))
Winblad, Bengt (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society)
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience)
Duits, Flora (Amsterdam UMC. University Medical Center)
Teunissen, Charlotte E. (Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands)
Universitat Autònoma de Barcelona

Fecha:	2017
Resumen:	Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the diagnostic workup of several neurological brain diseases. Reluctance to perform the procedure is among others due to a lack of standards and guidelines to minimize the risk of complications, such as post-LP headache or back pain. We provide consensus guidelines for the LP procedure to minimize the risk of complications. The recommendations are based on (1) data from a large multicenter LP feasibility study (evidence level II-2), (2) systematic literature review on LP needle characteristics and post-LP complications (evidence level II-2), (3) discussion of best practice within the Joint Programme Neurodegenerative Disease Research Biomarkers for Alzheimer's disease and Parkinson's Disease and Biomarkers for Multiple Sclerosis consortia (evidence level III). Our consensus guidelines address contraindications, as well as patient-related and procedure-related risk factors that can influence the development of post-LP complications. When an LP is performed correctly, the procedure is well tolerated and accepted with a low complication rate.
Nota:	Altres ajuts: This is an EU Joint Programme-Neurodegenerative Disease Research (JPND) project. The project is supported through the following funding organizations under the aegis of JPND-www.jpnd.eu: Ministry of Health (Italy), Fundaçao para a Ciência e a Tecnologia (Portugal), Instituto de Salud Carlos III (Spain), The Swedish Research Council (Sweden), ZonMw (The Netherlands)
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Lumbar puncture ; Cerebrospinal fluid ; Post-LP complications ; Headache ; Back pain ; Consensus guidelines ; Evidence-based guidelines
Publicado en:	Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 8 (may 2017) , p. 111-126, ISSN 2352-8729

DOI: 10.1016/j.dadm.2017.04.007
PMID: 28603768

16 p, 688.9 KB

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