Elvin, Johannes - Resultats de la cerca - Dipòsit Digital de Documents de la UAB

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Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance / Grünberg, John R. (Sahlgrenska Academy at the University of Gothenburg. The Lundberg Laboratory for Diabetes Research) ; Hoffmann, Jenny M. (Sahlgrenska Academy at the University of Gothenburg. The Lundberg Laboratory for Diabetes Research) ; Hedjazifar, Shahram (Sahlgrenska Academy at the University of Gothenburg. The Lundberg Laboratory for Diabetes Research) ; Nerstedt, Annika (Sahlgrenska Academy at the University of Gothenburg. The Lundberg Laboratory for Diabetes Research) ; Jenndahl, Lachmi (Sahlgrenska Academy at the University of Gothenburg. The Lundberg Laboratory for Diabetes Research) ; Elvin, Johannes (Sahlgrenska Academy at the University of Gothenburg. The Lundberg Laboratory for Diabetes Research) ; Castellot, John (Department of Integrative Physiology and Pathobiology, Tufts University School of Medicine) ; Wei, Lan (Massachusetts General Hospital (Boston)) ; Movérare-Skrtic, Sofia (Sahlgrenska Academy at the University of Gothenburg. Centre for Bone and Arthritis Research) ; Ohlsson, Claes (Sahlgrenska Academy at the University of Gothenburg. Centre for Bone and Arthritis Research) ; Holm, Louise Mannerås (Sahlgrenska Academy at the University of Gothenburg. The Wallenberg Laboratory) ; Bäckhed, Fredrik (University of Copenhagen. Novo Nordisk Foundation Center for Basic Metabolic Research) ; Syed, Ismail (Beth Israel Deaconess and Harvard Medical School) ; Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ; Saghatelian, Alan (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica)) ; Kahn, Barbara B. (Beth Israel Deaconess and Harvard Medical School) ; Hammarstedt, Ann (Sahlgrenska Academy at the University of Gothenburg. The Lundberg Laboratory for Diabetes Research) ; Smith, Ulf (Sahlgrenska Academy at the University of Gothenburg. The Lundberg Laboratory for Diabetes Research)
WISP2 is a novel adipokine, most highly expressed in the adipose tissue and primarily in undifferentiated mesenchymal cells. As a secreted protein, it is an autocrine/paracrine activator of canonical WNT signaling and, as an intracellular protein, it helps to maintain precursor cells undifferentiated. [...]
2017 - DOI (Digital Object Identifier)

10.1038/srep43515
Scientific reports, Vol. 7 (02 2017)

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