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1.
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13 p, 527.1 KB |
Autonomic response to walk tests is useful for assessing outcome measures in people with multiple sclerosis
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Kontaxis, Spyridon (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Laporta, Estela (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Garcia, Esther (Universitat Autònoma de Barcelona. Departament de Microelectrònica i Sistemes Electrònics) ;
Guerrero, Ana Isabel (Hospital Universitari Vall d'Hebron) ;
Zabalza, Ana (Hospital Universitari Vall d'Hebron) ;
Matteo, Martinis (Vita Salute San Raffaele University) ;
Lucia, Roselli (Vita Salute San Raffaele University) ;
Simblett, Sara (King's College London) ;
Weyer, Janice (RADAR-CNS Patient Advisory Board) ;
Hotopf, Matthew (King's College London) ;
Narayan, Vaibhav A. (Research and Development Information Technology) ;
Rashid, Zulqarnain (King's College London) ;
Folarin, Amos A. (University College London) ;
Dobson, Richard J. B. (University College London) ;
Buron, Mathias Due (Copenhagen University Hospital Rigshospitalet) ;
Leocani, Letizia (Vita Salute San Raffaele University) ;
Cummins, Nicholas (King's College London) ;
Vairavan, Srinivasan (Research and Development Information Technology) ;
Costa, Gloria Dalla (Vita Salute San Raffaele University) ;
Magyari, Melinda (Copenhagen University Hospital Rigshospitalet) ;
Sørensen, Per Soelberg (Copenhagen University Hospital Rigshospitalet) ;
Nos, Carlos (Hospital Universitari Vall d'Hebron) ;
Bailón, Raquel (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Comi, Giancarlo (Casa di Cura del Policlinico (Milà, Itàlia)) ;
the RADAR-CNS Consortium, None (The RADAR-CNS Consortium)
The aim of this study was to evaluate the association between changes in the autonomic control of cardiorespiratory system induced by walk tests and outcome measures in people with Multiple Sclerosis (pwMS). [...]
2023 -  10.3389/fphys.2023.1145818
Frontiers in physiology, Vol. 14 (april 2023)
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11 p, 732.4 KB |
Automatic Assessment of the 2-Minute Walk Distance for Remote Monitoring of People with Multiple Sclerosis
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Kontaxis, Spyridon (Universidad de Zaragoza) ;
Laporta, Estela (Universidad de Zaragoza) ;
Garcia, Esther (Universitat Autònoma de Barcelona. Departament de Microelectrònica i Sistemes Electrònics) ;
Martinis, Matteo (University Vita-Salute and Hospital San Raffaele) ;
Leocani, Letizia (University Vita-Salute and Hospital San Raffaele) ;
Roselli, Lucia (University Vita-Salute and Hospital San Raffaele) ;
Buron, Mathias Due (Copenhagen University Hospital Rigshospitalet) ;
Guerrero, Ana Isabel (Hospital Universitari Vall d'Hebron) ;
Zabalza, Ana (Hospital Universitari Vall d'Hebron) ;
Cummins, Nicholas (King's College London) ;
Vairavan, Srinivasan (Janssen Research and Development) ;
Hotopf, Matthew (King's College London) ;
Dobson, Richard J. B. (University College London) ;
Narayan, Vaibhav A. (Davos Alzheimer's Collaborative) ;
La Porta, Maria Libera (University Vita-Salute and Hospital San Raffaele) ;
Costa, Gloria Dalla (University Vita-Salute and Hospital San Raffaele) ;
Magyari, Melinda (Copenhagen University Hospital Rigshospitalet) ;
Sørensen, Per Soelberg (Copenhagen University Hospital Rigshospitalet) ;
Nos, Carlos (Hospital Universitari Vall d'Hebron) ;
Bailón, Raquel (Universidad de Zaragoza) ;
Comi, Giancarlo (Casa di Cura del Policlinico (Milà, Itàlia))
The aim of this study was to investigate the feasibility of automatically assessing the 2-Minute Walk Distance (2MWD) for monitoring people with multiple sclerosis (pwMS). For 154 pwMS, MS-related clinical outcomes as well as the 2MWDs as evaluated by clinicians and derived from accelerometer data were collected from a total of 323 periodic clinical visits. [...]
2023 - 10.3390/s23136017
Sensors (Basel, Switzerland), Vol. 23 (june 2023)
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3.
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0 p, 615.7 KB |
Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues : Expert Guidelines
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Rossi, Simone (University of Siena) ;
Antal, Andrea (Otto-Guericke University Magdeburg) ;
Bestmann, Sven (UCL Institute of Neurology (Regne Unit)) ;
Bikson, Marom (The City College of New York) ;
Brewer, Carmen (National Institute on Deafness and Other Communication Disorders) ;
Brockmöller, Jürgen (Georg-August University of Goettingen) ;
Carpenter, Linda L. (Butler Hospital) ;
Cincotta, Massimo (Central Tuscany Local Health Authority) ;
Chen, Robert (University of Toronto) ;
Daskalakis, Jeff D. (University of Toronto) ;
Di Lazzaro, Vincenzo (Università Campus Bio-Medico) ;
Fox, Michael D. (Massachusetts General Hospital) ;
George, Mark S. (Medical University of South Carolina) ;
Gilbert, Donald (University of Cincinnati College of Medicine) ;
Kimiskidis, Vasilios K. (AHEPA University Hospital (Grècia)) ;
Koch, Giacomo (IRCCS Santa Lucia) ;
Ilmoniemi, Risto J. (Aalto University School of Science) ;
Lefaucheur, Jean Pascal (Assistance Publique Hôpitaux de Paris) ;
Leocani, Letizia (Vita-Salute San Raffaele University) ;
Lisanby, Sarah H. (Duke University) ;
Miniussi, Carlo (University of Trento) ;
Padberg, Frank (University Hospital Munich) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Paulus, Walter (Georg-August University of Goettingen) ;
Peterchev, Angel V. (Duke University) ;
Quartarone, Angelo (University of Messina) ;
Rotenberg, Alexander (Harvard Medical School) ;
Rothwell, John (UCL Institute of Neurology (Regne Unit)) ;
Rossini, Paolo M. (IRCCS San Raffaele-Pisana) ;
Santarnecchi, Emiliano (Beth Israel Deaconess Medical Center) ;
Shafi, Mouhsin M. (Beth Israel Deaconess Medical Center) ;
Siebner, Hartwig R. (University of Copenhagen) ;
Ugawa, Yoshikatzu (Fukushima Medical University) ;
Wassermann, Eric M. (National Institute of Neurological Disorders and Stroke) ;
Zangen, Abraham (Ben Gurion University) ;
Ziemann, Ulf (University of Tübingen) ;
Hallett, Mark (National Institutes of Health (NIH)) ;
Universitat Autònoma de Barcelona
This article is based on a consensus conference, promoted and supported by the International Federation of Clinical Neurophysiology (IFCN), which took place in Siena (Italy) in October 2018. The meeting intended to update the ten-year-old safety guidelines for the application of transcranial magnetic stimulation (TMS) in research and clinical settings (). [...]
2020 - 10.1016/j.clinph.2020.10.003
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, Vol. 132 (october 2020) , p. 269-306
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4.
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11 p, 1.0 MB |
Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study
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Balk, Lisanne J. (Vrije Universiteit Amsterdam) ;
Coric, Danko (Vrije Universiteit Amsterdam) ;
Knier, Benjamin (Technische Universität München) ;
Zimmermann, Hanna G. (Charité - Universitätsmedizin Berlin) ;
Behbehani, Raed (Ibn Sina Hospital, Kuwait) ;
Alroughani, Raed (Amiri Hospital, Kuwait) ;
Martinez-Lapiscina, Elena H. (Hospital Clínic i Provincial de Barcelona) ;
Brandt, Alexander U. (Charité - Universitätsmedizin Berlin) ;
Sánchez-Dalmau, Bernardo (Hospital Clínic i Provincial de Barcelona) ;
Vidal-Jordana, Angela (Hospital Universitari Vall d'Hebron) ;
Albrecht, Philipp (Heinrich Heine University) ;
Koska, Valeria (Heinrich Heine University) ;
Havla, Joachim (Ludwig-Maximilians Universitaet Muenchen) ;
Pisa, Marco (Vita-Salute San Raffaele University) ;
Nolan, Rachel C. (New York University School of Medicine) ;
Leocani, Letizia (Vita-Salute San Raffaele University) ;
Paul, Friedemann (Max Delbrueck Center for Molecular Medicine and Charité - Universitätsmedizin Berlin) ;
Aktas, Orhan (Heinrich Heine University) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Balcer, Laura J. (New York University School of Medicine) ;
Villoslada, Pablo (Hospital Clínic i Provincial de Barcelona) ;
Outteryck, Olivier (Université Lille) ;
Korn, Thomas (Munich Cluster for Systems Neurology (SyNergy)) ;
Petzold, Axel (Moorfields Eye Hospital & The National Hospital for Neurology and Neurosurgery) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background: The association of peripapillary retinal nerve fibre layer (pRNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness with neurodegeneration in multiple sclerosis (MS) is well established. [...]
2019 - 10.1177/2055217319871582
Multiple Sclerosis Journal - Experimental, Translational and Clinical, Vol. 5 Núm. 3 (2019)
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10 p, 554.6 KB |
Early Reduction of MRI Activity During 6 Months of Treatment With Cladribine Tablets for Highly Active Relapsing Multiple Sclerosis
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De Stefano, Nicola (Hospital Universitari Vall d'Hebron) ;
Barkhof, Frederik (Hospital Universitari Vall d'Hebron) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Achiron, Anat (Hospital Universitari Vall d'Hebron) ;
Derfuss, Tobias (Hospital Universitari Vall d'Hebron) ;
Chan, Andrew (Hospital Universitari Vall d'Hebron) ;
Hodgkinson, Suzanne (Hospital Universitari Vall d'Hebron) ;
Prat, Alexandre (Hospital Universitari Vall d'Hebron) ;
Leocani, Letizia (Hospital Universitari Vall d'Hebron) ;
Schmierer, Klaus (Hospital Universitari Vall d'Hebron) ;
Sellebjerg, Finn (Hospital Universitari Vall d'Hebron) ;
Vermersch, Patrick (Hospital Universitari Vall d'Hebron) ;
Wiendl, Heinz (Hospital Universitari Vall d'Hebron) ;
Keller, Birgit (Hospital Universitari Vall d'Hebron) ;
Roy, Sanjeev (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
The onset of action for high-efficacy immunotherapies in multiple sclerosis (MS) is an important parameter. This study (MAGNIFY-MS) evaluates the onset of action of cladribine tablets by observing changes in combined unique active (CUA) MRI lesion counts during the first 6 months of treatment in patients with highly active relapsing MS. [...]
2022 - 10.1212/NXI.0000000000001187
Neurology® neuroimmunology & neuroinflammation, Vol. 9 (june 2022)
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11 p, 760.7 KB |
Specific Patterns of Immune Cell Dynamics May Explain the Early Onset and Prolonged Efficacy of Cladribine Tablets
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Wiendl, Heinz (Hospital Universitari Vall d'Hebron) ;
Schmierer, Klaus (Hospital Universitari Vall d'Hebron) ;
Hodgkinson, Suzanne (Hospital Universitari Vall d'Hebron) ;
Derfuss, Tobias (Hospital Universitari Vall d'Hebron) ;
Chan, Andrew (Hospital Universitari Vall d'Hebron) ;
Sellebjerg, Finn (Hospital Universitari Vall d'Hebron) ;
Achiron, Anat (Hospital Universitari Vall d'Hebron) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Prat, Alexandre (Hospital Universitari Vall d'Hebron) ;
De Stefano, Nicola (Hospital Universitari Vall d'Hebron) ;
Barkhof, Frederik (Hospital Universitari Vall d'Hebron) ;
Leocani, Letizia (Hospital Universitari Vall d'Hebron) ;
Vermersch, Patrick (Hospital Universitari Vall d'Hebron) ;
Chudecka, Anita (Hospital Universitari Vall d'Hebron) ;
Mwape, Claire (Hospital Universitari Vall d'Hebron) ;
Holmberg, Kristina H. (Hospital Universitari Vall d'Hebron) ;
Boschert, Ursula (Hospital Universitari Vall d'Hebron) ;
Roy, Sanjeev (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Cladribine tablets cause a reduction in lymphocytes with a predominant effect on B-cell and T-cell counts. The MAGNIFY-MS substudy reports the dynamic changes on multiple peripheral blood mononuclear cell (PBMC) subtypes and immunoglobulin (Ig) levels over 12 months after the first course of cladribine tablets in patients with highly active relapsing multiple sclerosis (MS). [...]
2022 - 10.1212/NXI.0000000000200048
Neurology® neuroimmunology & neuroinflammation, Vol. 10 (november 2022)
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20 p, 2.4 MB |
Biopsychosocial Response to the COVID-19 Lockdown in People with Major Depressive Disorder and Multiple Sclerosis
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Siddi, Sara (Parc Sanitari Sant Joan de Déu) ;
Giné-Vázquez, Iago (Parc Sanitari Sant Joan de Déu) ;
Bailón, Raquel (Universidad de Zaragoza) ;
Matcham, Faith (University of Sussex) ;
Lamers, Femke (Amsterdam Public Health Research Institute) ;
Kontaxis, Spyridon (Centros de Investigación Biomédica en Red en el Área de Bioingeniería) ;
Laporta, Estela (Centros de Investigación Biomédica en Red en el Área de Bioingeniería) ;
Garcia, Esther (Universitat Autònoma de Barcelona. Departament de Microelectrònica i Sistemes Electrònics) ;
Arranz, Belén (Parc Sanitari Sant Joan de Déu) ;
Dalla Costa, Giancarlo (Vita-Salute San Raffaele University) ;
Guerrero, Ana Isabel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Zabalza, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Buron, Mathias Due (Copenhagen University Hospital Rigshospitalet) ;
Comi, Giancarlo (Vita-Salute San Raffaele University) ;
Leocani, Letizia (Scientific Institute San Raffaele) ;
Annas, Peter (H. Lundbeck A/S) ;
Hotopf, Matthew (King's College London) ;
Penninx, Benda W. J. (Amsterdam Public Health Research Institute) ;
Magyari, Melinda (Copenhagen University Hospital Rigshospitalet) ;
Sørensen, Per S. (Copenhagen University Hospital Rigshospitalet) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lavelle, Grance (King's College London) ;
Ivan, Alina (King's College London) ;
Oetzmann, Carolin (King's College London) ;
White, katie M. (King's College London) ;
Difrancesco, Sonia (Vrije Universiteit) ;
Locatelli, Patrick (University of Bergamo) ;
Mohr, David C. (Northwestern University) ;
Aguiló Llobet, Jordi (Universitat Autònoma de Barcelona. Departament de Microelectrònica i Sistemes Electrònics) ;
Narayan, Vaibhav (Janssen Research Development) ;
Folarin, Amoros (King's College London) ;
Dobson, Richard J.B. (King's College London) ;
Dineley, Judith (King's College London) ;
Leightley, Daniel (King's College London) ;
Cummins, Nicholas (King's College London) ;
Vairavan, Srinivasan (Janssen Research Development) ;
Ranjan, Yathart (King's College London) ;
Rashid, Zulqarnain (King's College London) ;
Rintala, Aki (LAB University of Applied Sciences) ;
Girolamo, Giovanni De (IRCCS Instituto Centro San Giovanni di Dio Fatebenefratelli) ;
Preti, Antonio (Università degli Studi di Torino) ;
Simblett, Sara (King's College London) ;
Wykes, Til (King's College London) ;
Myin-Germeys, Inez (Katholieke Universiteit Leuven) ;
Haro Abad, Josep Maria (Parc Sanitari Sant Joan de Déu)
Changes in lifestyle, finances and work status during COVID-19 lockdownsmay have led to biopsychosocial changes in people with pre-existing vulnerabilities such as MajorDepressive Disorders (MDDs) and Multiple Sclerosis (MS). [...]
2022 - 10.3390/jcm11237163
Journal of clinical medicine, Vol. 11 Núm. 23 (december 2022) , p. 7163
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