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33 p, 1.2 MB |
Metabotropic Glutamate Receptor 2 and Dopamine Receptor 2 Gene Expression Predict Sensorimotor Gating Response in the Genetically Heterogeneous NIH-HS Rat Strain
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Østerbøg, Tina Becher (Research Laboratory for Stereology and Neuroscience. Bispebjerg and Frederiksberg Hospitals. Copenhagen) ;
On, Doan Minh (Department of Physiology and Biophysics. Virginia Commonwealth University School of Medicine) ;
Oliveras, Ignasi (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Río-Álamos, Cristobal (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sánchez González, Ana (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Tapias-Espinosa, Carles (Departamento de Psiquiatría y Medicina Legal.) ;
Tobeña, Adolf 1950- (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Gonzalez-Maeso, Javier (Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine) ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Aznar, Susana (Bispebjerg and Frederiksberg Hospitals (Copenhagen, Dinamarca))
Disruption of sensorimotor gating causes "flooding" of irrelevant sensory input and is considered a congenital trait in several neurodevelopmental disorders. Prepulse inhibition of acoustic startle response (PPI) is the operational measurement and has a high translational validity. [...]
2020 -  10.1007/s12035-019-01829-w
Molecular neurobiology, Vol. 57 Núm. 3 (March 2020) , p. 1516-1528
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13 p, 1.4 MB |
Neural plasticity of the uterus : New targets for endometrial cancer?
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Español, Pia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Luna-Guibourg, Rocío (Institut d'Investigació Biomèdica Sant Pau) ;
Soler, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Caruana, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Altés-Arranz, Amanda (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Rodríguez-Lozano, Francisco (Institut d'Investigació Biomèdica Sant Pau) ;
Porta, Oriol (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sanchez-Garcia, Olga (Institut d'Investigació Biomèdica Sant Pau) ;
Llurba, E (Institut d'Investigació Biomèdica Sant Pau) ;
Rovira Negre, Ramon (Institut d'Investigació Biomèdica Sant Pau) ;
Céspedes, María Virtudes (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Endometrial carcinoma is the most common gynecological malignancy in Western countries and is expected to increase in the following years because of the high index of obesity in the population. Recently, neural signaling has been recognized as part of the tumor microenvironment, playing an active role in tumor progression and invasion of different solid tumor types. [...]
2022 - 10.1177/17455057221095537
Women's Health, Vol. 18 (april 2022)
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39 p, 2.7 MB |
Synthetic Photoswitchable Neurotransmitters Based on Bridged Azobenzenes
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Cabré Segura, Gisela (Universitat Autònoma de Barcelona. Departament de Química) ;
Garrido Charles, Aida (Institut de Bioenginyeria de Catalunya) ;
González-Lafont, Àngels (Universitat Autònoma de Barcelona. Departament de Química) ;
Moormann, Widukind (Christian Albrechts University Kiel. Otto Diels-Institute of Organic Chemistry) ;
Langbehn, Daniel (Christian Albrechts University Kiel. Otto Diels-Institute of Organic Chemistry) ;
Egea, David (Universitat Autònoma de Barcelona. Departament de Química) ;
Lluch López, Josep Maria (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Herges, Rainer (Christian Albrechts University Kiel. Otto Diels-Institute of Organic Chemistry) ;
Alibes, Ramón (Universitat Autònoma de Barcelona. Departament de Química) ;
Busqué Sánchez, Félix (Universitat Autònoma de Barcelona. Departament de Química) ;
Gorostiza, Pau (Institut de Bioenginyeria de Catalunya) ;
Hernando Campos, Jordi (Universitat Autònoma de Barcelona. Departament de Química)
Photoswitchable neurotransmitters of ionotropic kainate receptors were synthesized by tethering a glutamate moiety to disubstituted C2-bridged azobenzenes, which were prepared through a novel methodology that allows access to diazocines with higher yields and versatility. [...]
2019 - 10.1021/acs.orglett.9b01222
Organic Letters, Vol. 21, Issue 10 (May 2019) , p. 3780-3784
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30 p, 1.7 MB |
Consensus guideline for the diagnosis and treatment of tetrahydrobiopterin (BH) deficiencies
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Opladen, Thomas (University Children's Hospital. Division of Child Neurology and Metabolic Disorders) ;
López-Laso, Eduardo (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Cortès-Saladelafont, Elisenda (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pearson, Toni S. (Washington University School of Medicine. Department of Neurology) ;
Sivri, H. Serap (Hacettepe University, Faculty of Medicine. Department of Pediatrics, Section of Metabolism) ;
Yildiz, Yilmaz (Hacettepe University, Faculty of Medicine. Department of Pediatrics, Section of Metabolism) ;
Assmann, Birgit (University Children's Hospital. Division of Child Neurology and Metabolic Disorders) ;
Kurian, Manju A. (Great Ormond Street Hospital for Children (Londres)) ;
Leuzzi, Vincenzo (Sapienza University of Rome. Unit of Child Neurology and Psychiatry, Department of Human Neuroscience) ;
Heales, Simon (National Hospital. Neurometabolic Unit) ;
Pope, Simon (National Hospital. Neurometabolic Unit) ;
Porta, Francesco (AOU Città della Salute e della Scienza. Department of Pediatrics) ;
García-Cazorla, Angels (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Honzík, Tomáš (Charles University. Faculty of Medicine in Hradec Králové) ;
Pons, Roser (Aghia Sofia Hospital. First Department of Pediatrics of the University of Athens) ;
Regal, Luc (UZ Brussel. Department of Pediatric, Pediatric Neurology and Metabolism Unit) ;
Goez, Helly (University of Alberta Glenrose Rehabilitation Hospital. Department of Pediatrics) ;
Artuch, R. (Institut de Recerca Sant Joan de Déu) ;
Hoffmann, Georg F. (University Children's Hospital. Division of Child Neurology and Metabolic Disorders) ;
Horvath, Gabriella (University of British Columbia. Department of Pediatrics, Division of Biochemical Genetics, BC Children's Hospital) ;
Thöny, Beat (University Children's Hospital Zurich. Division of Metabolism) ;
Scholl-Bürgi, Sabine (Medical University of Innsbruck. Clinic for Pediatrics I) ;
Burlina, Alberto (Azienda Ospedaliera Universitaria di Padova) ;
Verbeek, Marcel M. (Radboud University Medical Centre. Departments of Neurology and Laboratory Medicine) ;
Mastrangelo, Mario (Sapienza University of Rome. Unit of Child Neurology and Psychiatry, Department of Human Neuroscience) ;
Friedman, Jennifer (Rady Children's Hospital Division of Neurology; Rady Children's Institute for Genomic Medicine. UCSD Departments of Neuroscience and Pediatrics) ;
Wassenberg, Tessa (UZ Brussel. Department of Pediatric, Pediatric Neurology and Metabolism Unit) ;
Jeltsch, Kathrin (University Children's Hospital. Division of Child Neurology and Metabolic Disorders) ;
Kulhánek, Jan (Charles University. Faculty of Medicine in Hradec Králové) ;
Kuseyri Hübschmann, Oya (University Children's Hospital. Division of Child Neurology and Metabolic Disorders) ;
Universitat Autònoma de Barcelona
Tetrahydrobiopterin (BH) deficiencies comprise a group of six rare neurometabolic disorders characterized by insufficient synthesis of the monoamine neurotransmitters dopamine and serotonin due to a disturbance of BH biosynthesis or recycling. [...]
2020 - 10.1186/s13023-020-01379-8
Orphanet Journal of Rare Diseases, Vol. 15 (may 2020)
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20 p, 1.3 MB |
Housing and road transport modify the brain neurotransmitter systems of pigs : Do pigs raised in different conditions cope differently with unknown environments?
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Arroyo, Laura (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Valent, Daniel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Carreras, Ricard (Institut de Recerca i Tecnologia Agroalimentàries) ;
Peña, R. (Universitat Autònoma de Barcelona. Servei de Bioquímica Clínica Veterinària.) ;
Sabrià i Pau, Josefa (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Velarde, Antonio (Institut de Recerca i Tecnologia Agroalimentàries) ;
Bassols Teixidó, Anna Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
How housing and transport conditions may affect welfare in porcine production is a leading topic in livestock research. This study investigated whether pigs present a different neurological response to management conditions and to ascertain whether pigs living partially outdoors cope differently with road transport-associated stress. [...]
2019 - 10.1371/journal.pone.0210406
PloS one, Vol. 14 Núm. 1 (january 2019) , p. e0210406
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13 p, 787.1 KB |
Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease
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Dekker, Alain D. (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ;
Vermeiren, Yannick (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ;
Carmona Iragui, María (Fundació Catalana Síndrome de Down) ;
Benejam, Bessy (Fundació Catalana Síndrome de Down) ;
Videla Toro, Laura (Fundació Catalana Síndrome de Down) ;
Gelpi, Ellen (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Aerts, Tony (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ;
Van Dam, Debby (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ;
Fernández, Susana (Fundació Catalana Síndrome de Down) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Videla, Sebastian (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Sieben, Anne (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ;
Martin, Jean-Jacques (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Fundació Catalana Síndrome de Down) ;
De Deyn, Peter Paul (University Hospital Antwerp (Bèlgica)) ;
Universitat Autònoma de Barcelona
People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. [...]
2017 - 10.1016/j.dadm.2017.11.001
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 10 (november 2017) , p. 99-111
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