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1.
12 p, 1.7 MB Pharmacokinetic and exposure-response analysis of pertuzumab in patients with HER2-positive metastatic gastric or gastroesophageal junction cancer / Kirschbrown, Whitney. P. (Clinical Pharmacology. Genentech Research and Early Development) ; Wang, B. (Clinical Pharmacology. Genentech Research and Early Development) ; Nijem, I. (Clinical Pharmacology. Genentech Research and Early Development) ; Ohtsu, A. (Department of Gastrointestinal Oncology. National Cancer Center Hospital East) ; Hoff, P. M. (Instituto do Câncer de São Paulo. Faculdade de Medicina da Universidade de São Paulo) ; Shah, M. A. (Medical Oncology/Solid Tumor Program. Sandra and Edward Meyer Cancer Center. Weill Cornell Medical College) ; Shen, L. (Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing). Department of Gastrointestinal Oncology. Peking University Cancer Hospital and Institute) ; Kang, Y. K. (Department of Oncology. Asan Medical Center. University of Ulsan College of Medicine) ; Alsina, Maria (Vall d'Hebron Institut d'Oncologia) ; Girish, S. (Clinical Pharmacology. Genentech Research and Early Development) ; Garg, Amit (Clinical Pharmacology. Genentech Research and Early Development) ; Universitat Autònoma de Barcelona
Purpose: To characterize the pharmacokinetics (PK) of pertuzumab and trastuzumab in patients with HER2-positive metastatic gastric or gastroesophageal junction cancer in the randomized, double-blind, phase III JACOB study (NCT01774786), and to evaluate the appropriateness of the pertuzumab regimen in these patients. [...]
2019 - 10.1007/s00280-019-03871-w
Cancer Chemotherapy and Pharmacology, Vol. 84 Núm. 3 (january 2019) , p. 539-550  
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2.
26 p, 3.5 MB A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigs / Cho, In-Cheol (Rural Development Administration. National Institute of Animal Science) ; Park, Hee-Bok (Kongju National University. College of Industrial Sciences. Department of Animal Resources Science) ; Ahn, Jin Seop (Korea Research Institute of Bioscience and Biotechnology. Biotherapeutics Translational Research Center) ; Han, Sang-Hyun (Jeju National University. Educational Science Research Institute) ; Lee, JaeBong (Chonbuk National University. Korea Zoonosis Research Institute) ; Lim, Hyun-Tae (Gyeongsang National University. College of Agriculture and Life Sciences) ; Yoo, Chae-Kyoung (Gyeongsang National University. Institute of Agriculture and Life Science.) ; Jung, Eun-Ji (Bio-Medical Science Co., Ltd) ; Kim, Dong-Hwan (Korea Research Institute of Bioscience and Biotechnology. Biotherapeutics Translational Research Center) ; Sun, Wu-Sheng (Korea Research Institute of Bioscience and Biotechnology. Biotherapeutics Translational Research Center) ; Ramayo-Caldas, Yuliaxis (Institut de Recerca i Tecnologia Agroalimentàries) ; Kim, Sang-Geum (Rural Development Administration. National Institute of Animal Science) ; Kang, Yong-Jun (Rural Development Administration. National Institute of Animal Science) ; Kim, YooKyung (Jeju National University. Educational Science Research Institute) ; Shin, Hyun-Sook (Rural Development Administration. National Institute of Animal Science) ; Seong, Pil-Nam (Rural Development Administration. National Institute of Animal Science) ; Hwang, In-Sul (Rural Development Administration. National Institute of Animal Science) ; Park, Beom-Young (Rural Development Administration. National Institute of Animal Science) ; Hwang, Seongsoo (Rural Development Administration. National Institute of Animal Science) ; Lee, Sung-Soo (Rural Development Administration. National Institute of Animal Science) ; Ryu, Youn-Chul (Jeju National University. Division of Biotechnology. SARI) ; Lee, Jun-Heon (Chungnam National University. Division of Animal and Dairy Science) ; Ko, MoonSuck (Rural Development Administration. National Institute of Animal Science) ; Lee, Kichoon (Ohio State University. College of Food Agricultural and Environmental Sciences) ; Andersson, Göran (Swedish University of Agricultural Sciences. Department of Animal Breeding and Genetics) ; Perez-Enciso, Miguel (Centre de Recerca en Agrigenòmica) ; Lee, JeongWoong (Korea Research Institute of Bioscience and Biotechnology. Biotherapeutics Translational Research Center)
Muscle development and lipid accumulation in muscle critically affect meat quality of livestock. However, the genetic factors underlying myofiber-type specification and intramuscular fat (IMF) accumulation remain to be elucidated. [...]
2019 - 10.1371/journal.pgen.1008279
PLoS Genetics, Vol. 15, Núm. 10 (October 2019) , art. e1008279  
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3.
23 p, 9.1 MB MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells / Sánchez-Cid, Lourdes (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Pons, Mònica (Institut de Biologia Molecular de Barcelona) ; Lozano, Juan José (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Rubio, Nuria (Institut de Química Avançada de Catalunya) ; Guerra-Rebollo, Marta (Institut de Química Avançada de Catalunya) ; Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Paris-Coderch, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Segura, Miquel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fueyo, Raquel (Institut de Biologia Molecular de Barcelona) ; Arguimbau, Judit (Institut de Biologia Molecular de Barcelona) ; Zodda, Erika (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Bermudo, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Alonso, Immaculada (Hospital Clínic i Provincial de Barcelona) ; Caparrós, Xavier (Hospital Clínic i Provincial de Barcelona) ; Cascante, Marta (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Rafii, Arash (Weill Cornell Medical College. Education City (Ar-Rayyan, Qatar)) ; Kang, Yibin (Princeton University. Department of Molecular Biology) ; Martínez-Balbás, Marian (Institut de Biologia Molecular de Barcelona) ; Weiss, Stephen J. (University of Michigan. Life Sciences Institute) ; Blanco Fernández, Jerónimo (Institut de Química Avançada de Catalunya) ; Muñoz, Montserrat (Hospital Clínic i Provincial de Barcelona) ; Fernández, Pedro L. (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut) ; Thomson, Timothy M. (Institut de Biologia Molecular de Barcelona) ; Universitat Autònoma de Barcelona
MicroRNAs are critical regulators of gene networks in normal and abnormal biological processes. Focusing on invasive ductal breast cancer (IDC), we have found dysregulated expression in tumor samples of several microRNAs, including the miR-200 family, along progression from primary tumors to distant metastases, further reflected in higher blood levels of miR-200b and miR-7 in IDC patients with regional or distant metastases relative to patients with primary node-negative tumors. [...]
2017 - 10.18632/oncotarget.20698
Oncotarget, Vol. 8, Num. 48 (October 2017) , p. 83384-83406  
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4.
23 p, 523.3 KB The Adaptation of English Liquids in Contemporary Korean : a Diachronic Study / Kang, Yoonjung (University of Toronto Scarborough. Centre for French and Linguistics)
This paper examines the diachronic development of English liquid adaptation in Contemporary Korean (1890-Present) based on a number of loanword lists from different time periods. The examination of initial liquids shows that contrary to common assumption, the initial liquids are often realized as [n], showing that the Tu?m rule (a rule of initial liquid avoidance) is still active, although marginally. [...]
2012 - 10.5565/rev/catjl.10
Catalan journal of linguistics, Vol. 11, Núm. (2012) , p. 41-63  
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Vegeu també: autors amb noms similars
1 Kang, Y. K.
3 Kang, Yibin
1 Kang, Yong-Jun
1 Kang, Yoon-Koo
2 Kang, Yoonjung
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