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Resultats globals: 3 registres trobats en 0.05 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
12 p, 484.6 KB Safety profile of the adjuvanted recombinant zoster vaccine : Pooled analysis of two large randomised phase 3 trials / López Fauqued, Marta (GlaxoSmithKline (GSK)) ; Campora, Laura (GlaxoSmithKline (GSK)) ; Delannois, Frédérique (GlaxoSmithKline (GSK)) ; El Idrissi, Mohamed (GlaxoSmithKline (GSK)) ; Oostvogels, Lidia (GlaxoSmithKline (GSK)) ; De Looze, Ferdinandus (University of Queensland) ; Diez-Domingo, Javier (Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat (València)) ; Heineman, Thomas (GlaxoSmithKline (GSK)) ; Lal, Himal (GlaxoSmithKline (GSK)) ; McElhaney, Janet (Health Sciences North Research Institute) ; McNeil, Shelly (Dalhousie University) ; Yeo, Wilfred (University of Wollongong) ; Tavares-Da-Silva, Fernanda (GlaxoSmithKline (GSK)) ; Ahonen, Anitta (University of Tampere) ; Avelino-Silva, Thiago (University of São Paulo Medical School) ; Barba-Gomez, José Fernando (Instituto Dermatológico de Jalisco) ; Berglund, Johan (Blekinge Institute of Technology) ; Brotons, Carlos (Institut d'Investigació Biomèdica Sant Pau) ; Caso, Covadonga (Hospital Clínico San Carlos (Madrid)) ; Chlibek, Roman (University of Defence) ; Choi, Won Suk (Korea University College of Medicine) ; Cunningham, Anthony (University of Sydney) ; Desole, Maria Giuseppina (Servizio di Igiene Pubblica) ; Eizenberg, Peter (Doctors of Ivanhoe) ; Esen, Meral (University Clinic of Tübingen) ; Espié, Emmanuelle (GlaxoSmithKline (GSK)) ; Gervais, Pierre (Q&T Research Sherbrooke) ; Ghesquiere, Wayne (University of British Columbia) ; Godeaux, Olivier O. (GlaxoSmithKline (GSK)) ; Gorfinkel, Iris (York University) ; Hui, David Shu Cheong (Prince of Wales Hospital (Australia)) ; Hwang, Shinnjang (Taipei Veterans General Hospital and National Yang Ming University School of Medicine) ; Korhonen, Tiina (University of Tampere Medical School) ; Kovac, Martina (GlaxoSmithKline (GSK)) ; Ledent, Edouard Y. (GlaxoSmithKline (GSK)) ; Leung, Edward Man Fuk (Hong Kong Association of Gerontology) ; Levin, Myron (University of Colorado Anschutz Medical Campus) ; Perez, Silvia Narejos (CAP Centelles) ; de Andrade Neto, José Luiz (Instituto A. Z. de Pesquisa e Ensino) ; Pauksens, Karlis (Uppsala University Hospital) ; Poder, Airi (Kliiniliste Uuringute Keskus) ; Rodriguez de la Pinta, Maria Luisa (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Rombo, Lars (Uppsala University) ; Schwarz, Tino Francis (Standort Juliusspital) ; Smetana, Jan (University of Defence) ; Staniscia, Tommaso (University G. d'Annunzio of Chieti-Pescara) ; Tinoco-Fávila, Juan Carlos (Hospital General de Durango) ; Toma, Azhar (Manna Research) ; Vastiau, Ilse (GlaxoSmithKline (GSK)) ; Vesikari, Timo H. (University of Tampere) ; Volpi, Antonio (A.O. Univesitaria Policlinico Tor Vergata) ; Watanabe, Daisuke (Kobe University Graduate School of Medicine) ; Weckx, Lily (Federal University of Sao Paulo) ; Zahaf, Toufik (GlaxoSmithKline (GSK)) ; Universitat Autònoma de Barcelona
The ZOE-50 (NCT01165177) and ZOE-70 (NCT01165229) phase 3 clinical trials showed that the adjuvanted recombinant zoster vaccine (RZV) was ≥90% efficacious in preventing herpes zoster in adults. Here we present a comprehensive overview of the safety data from these studies. [...]
2019 - 10.1016/j.vaccine.2019.03.043
Vaccine, Vol. 37 Núm. 18 (24 2019) , p. 2482-2493  
Registre complet - Creative Commons
2.
10 p, 3.3 MB Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome / Polex-Wolf, Joseph (Medical Research Council (MRC) Metabolic Diseases Unit) ; Lam, Brian Y. H. (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories) ; Larder, Rachel (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories) ; Tadross, John (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories) ; Rimmington, Debra (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories) ; Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ; Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Cenzano, Verónica Jiménez (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ; Ayuso, Eduard (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ; Ma, Marcella K. L. (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories) ; Rainbow, Kara (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories) ; Coll, Anthony P. (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories) ; O'Rahilly, Stephen (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories) ; Yeo, Giles S. H. (Medical Research Council (MRC) Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories)
Profound hyperphagia is a major disabling feature of Prader-Willi syndrome (PWS). Characterization of the mechanisms that underlie PWS-associated hyperphagia has been slowed by the paucity of animal models with increased food intake or obesity. [...]
2018 - 10.1172/JCI97007
The journal of clinical investigation, Vol. 128 (january 2018) , p. 960-969  
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3.
8 p, 490.0 KB Hypothalamic-specific manipulation of Fto , the ortholog of the human obesity gene FTO , affects food intake in rats / Tung, Yi-Chun Loraine (University of Cambridge. Metabolic Research Laboratories) ; Ayuso, Eduard (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Shan, Xiaoye (University of Cambridge. Metabolic Research Laboratories) ; Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; O'Rahilly, Stephen (University of Cambridge. Metabolic Research Laboratories) ; Coll, Anthony P. (University of Cambridge. Metabolic Research Laboratories) ; Yeo, Gilles S. H. (University of Cambridge. Metabolic Research Laboratories)
Sequence variants in the first intron of FTO are strongly associated with human obesity and human carriers of the risk alleles show evidence for increased appetite and food intake. Mice globally lacking Fto display a complex phenotype characterised by both increased energy expenditure and increased food intake. [...]
2010 - 10.1371/journal.pone.0008771
PloS one, Vol. 5, Issue 1 (January 2010) , p. e8771  
Registre complet - Creative Commons

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