UAB Digital Repository of Documents 3 records found  Search took 0.00 seconds. 
1.
15 p, 1.6 MB A trans-omics assessment of gene-gene interaction in early-stage NSCLC / Chen, Jiajin (Nanjing Medical University) ; Song, Yunjie (Department of Biostatistics. Nanjing Medical University) ; Li, Yi (Department of Biostatistics. University of Michigan) ; Wei, Yongyue (Nanjing Medical University) ; Shen, Sipeng (Department of Biostatistics. Nanjing Medical University) ; Zhao, Yang (Department of Biostatistics. Nanjing Medical University) ; You, Dongfang (Department of Biostatistics. Nanjing Medical University) ; Su, Li (Harvard Medical School) ; Bjaanæs, Maria Moksnes (Department of Cancer Genetics Oslo University Hospital) ; Karlsson, Anna (Department of Clinical Sciences. Lund University) ; Planck, Maria (Department of Clinical Sciences. Lund University) ; Staaf, Johan (Department of Clinical Sciences. Lund University) ; Helland, Åslaug (Institute of Clinical Medicine. University of Oslo) ; Esteller, M (Universitat de Barcelona) ; Shen, Hongbing (Nanjing Medical University) ; Christiani, David C. (Harvard Medical School) ; Zhang, Ruyang (Nanjing Medical University) ; Chen, Feng (State Key Laboratory of Reproductive Medicine. Nanjing Medical University)
Epigenome-wide gene-gene (G × G) interactions associated with non-small-cell lung cancer (NSCLC) survival may provide insights into molecular mechanisms and therapeutic targets. Hence, we proposed a three-step analytic strategy to identify significant and robust G × G interactions that are relevant to NSCLC survival. [...]
2023 - 10.1002/1878-0261.13345
Molecular Oncology, Vol. 17 Núm. 1 (january 2023) , p. 173-187  
2.
15 p, 2.0 MB Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC / Ji, Xinyu (Nanjing Medical University) ; Lin, Lijuan (Nanjing Medical University) ; Fan, Juanjuan (Nanjing Medical University) ; Li, Yi (University of Michigan) ; Wei, Yongyue (Nanjing Medical University) ; Shen, Sipeng (Nanjing Medical University) ; Su, Li (Harvard T.H. Chan School of Public Health (Estats Units d'Amèrica)) ; Shafer, Andrea (Harvard Medical School) ; Bjaanæs, Maria Moksnes (Oslo University Hospital (Oslo, Noruega)) ; Karlsson, Anna (Lund University) ; Planck, Maria (Lund University) ; Staaf, Johan (Lund University) ; Helland, Åslaug (University of Oslo) ; Esteller, M (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zhang, Ruyang (Nanjing Medical University) ; Chen, Feng (Nanjing Medical University) ; Christiani, David C (Harvard Medical School) ; Universitat Autònoma de Barcelona
The interaction between DNA methylation of tripartite motif containing 27 (cg05293407) and smoking has previously been identified to reveal histologically heterogeneous effects of TRIM27 DNA methylation on early-stage non-small-cell lung cancer (NSCLC) survival. [...]
2022 - 10.1002/1878-0261.13167
Molecular Oncology, Vol. 16 Núm. 3 (february 2022) , p. 717-731  
3.
14 p, 3.9 MB Age-related metabolic changes limit efficacy of deoxynucleoside-based therapy in thymidine kinase 2-deficient mice / Blázquez-Bermejo, Cora (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Molina-Granada, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vila-Julià, Ferran (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jiménez-Heis, Daniel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Zhou, Xiaoshan (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Torres-Torronteras, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Karlsson, Anna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Martí, Ramon A. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Cámara, Yolanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Thymidine kinase 2 (TK2) catalyses the phosphorylation of deoxythymidine (dThd) and deoxycytidine (dCtd) within mitochondria. TK2 deficiency leads to mtDNA depletion or accumulation of multiple deletions. [...]
2019 - 10.1016/j.ebiom.2019.07.042
EBioMedicine, Vol. 46 (july 2019) , p. 342-355  

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8 Karlsson, A.
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