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14 p, 1.3 MB |
A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials
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Sforzini, Luca (King's College London) ;
Worrell, Courtney (King's College London) ;
Kose, Melisa (King's College London) ;
Anderson, Ian M. (The University of Manchester and Manchester Academic Health Sciences Centre) ;
Aouizerate, Bruno (University of Bordeaux) ;
Arolt, Volker (University of Münster) ;
Bauer, Michael (University Hospital Carl Gustav Carus) ;
Baune, Bernhard T. (The University of Melbourne) ;
Cleare, Anthony J. (National Institute for Health Research Mental Health Biomedical Research Centre) ;
Cowen, Philip J. (University of Oxford) ;
Dinan, Timothy G. (University College Cork) ;
Fagiolini, Andrea (University of Siena) ;
Ferrier, I. Nicol (Newcastle University) ;
Hegerl, Ulrich (Goethe University) ;
Krystal, Andrew D. (Duke University School of Medicine) ;
Leboyer, Marion (Université Paris Est Creteil (UPEC)) ;
McAllister-Williams, R. Hamish (Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust) ;
McIntyre, Roger S. (Brain and Cognition Discovery Foundation) ;
Meyer-Lindenberg, Andreas (Heidelberg University) ;
Miller, Andrew H. (Emory University School of Medicine) ;
Nemeroff, Charles B. (University of Texas at Austin) ;
Normann, Claus (Medical Center - University of Freiburg) ;
Nutt, David (Imperial College) ;
Pallanti, Stefano (University of Florence) ;
Pani, Luca (VeraSci) ;
Penninx, Brenda W. J. H. (Vrije Universiteit and GGZinGeest) ;
Schatzberg, Alan F. (Stanford University) ;
Shelton, Richard C. (University of Alabama at Birmingham) ;
Yatham, Lakshmi N. (University of British Columbia) ;
Young, Allan H. (National Institute for Health Research Mental Health Biomedical Research Centre) ;
Zahn, Roland (National Institute for Health Research Mental Health Biomedical Research Centre) ;
Aislaitner, Georgios (Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM)) ;
Butlen-Ducuing, Florence (European Medicines Agency) ;
Fletcher, Christine (Biostatistics, GlaxoSmithKline) ;
Haberkamp, Marion (Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM)) ;
Laughren, Thomas (Laughren Psychopharm Consulting) ;
Mäntylä, Fanni-Laura (GAMIAN-Europe (Global Alliance of Mental Illness Advocacy Networks-Europe)) ;
Schruers, Koen (University of Leuven) ;
Thomson, Andrew (European Medicines Agency) ;
Arteaga-Henríquez, Gara (Hospital Universitari Vall d'Hebron) ;
Benedetti, Francesco (IRCCS Scientific Institute Ospedale San Raffaele) ;
Cash-Gibson, Lucinda (Hospital Universitari Vall d'Hebron) ;
Chae, Woo Ri (Charité - Universitätsmedizin Berlin) ;
De Smedt, Heidi (Janssen Research & Development) ;
Gold, Stefan M. (University Medical Center Hamburg-Eppendorf) ;
Hoogendijk, Witte J. G. (Erasmus University Medical Centre) ;
Mondragón, Valeria Jordán (Medical Director Neuroscience for Region Europe at Novartis Pharma) ;
Maron, Eduard (West Tallinn Central Hospital) ;
Martynowicz, Jadwiga (Janssen Research & Development) ;
Melloni, Elisa (IRCCS Scientific Institute Ospedale San Raffaele) ;
Otte, Christian (Charité - Universitätsmedizin Berlin) ;
Perez-Fuentes, Gabriela (Hospital Universitari Vall d'Hebron) ;
Poletti, Sara (IRCCS Scientific Institute Ospedale San Raffaele) ;
Schmidt, Mark E. (Janssen Pharmaceutica NV) ;
van de Ketterij, Edwin (European Infrastructure for Translational Medicine (EATRIS)) ;
Woo, Katherine (Janssen Research & Development) ;
Flossbach, Yanina (Novartis Pharma AG) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Savitz, Adam J. (Department of Neuroscience) ;
Pariante, Carmine M (National Institute for Health Research Mental Health Biomedical Research Centre) ;
Universitat Autònoma de Barcelona
Criteria for treatment-resistant depression (TRD) and partially responsive depression (PRD) as subtypes of major depressive disorder (MDD) are not unequivocally defined. In the present document we used a Delphi-method-based consensus approach to define TRD and PRD and to serve as operational criteria for future clinical studies, especially if conducted for regulatory purposes. [...]
2021 -  10.1038/s41380-021-01381-x
Molecular psychiatry, Vol. 27 (december 2021) , p. 1286-1299
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12 p, 1.5 MB |
Ten facts about land systems for sustainability
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Meyfroidt, Patrick (Fonds de la Recherche Scientifique) ;
De Bremond, Ariane (University of Maryland) ;
Ryan, Casey M. (University of Edinburgh) ;
Archer, Emma (University of Pretoria) ;
Aspinall, Richard (James Hutton Institute) ;
Chhabra, Abha (Indian Space Research Organisation) ;
Camara, Gilberto (National Institute for Space Research) ;
Corbera, Esteve (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ;
DeFries, Ruth (Columbia University) ;
Díaz, Sandra (Universidad Nacional de Córdoba) ;
Dong, Jinwei (Chinese Academy of Sciences) ;
Ellis, Erle C. (University of Maryland. Baltimore County) ;
Erb, Karl-Heinz (University of Natural Resources and Life Sciences) ;
Fisher, Janet A. (University of Edinburgh) ;
Garrett, Rachael D. (ETH Zürich) ;
Golubiewski, Nancy E. (Ministry for the Environment) ;
Grau, H. Ricardo (Universidad Nacional de Tucumán. Consejo Nacional de Investigaciones Científicas y Técnicas) ;
Grove, J. Morgan (Baltimore Urban Field Station) ;
Haberl, Helmut (University of Natural Resources and Life Sciences) ;
Heinimann, Andreas (University of Bern) ;
Hostert, Patrick (Humboldt-Universität zu Berlin) ;
Jobbágy, Esteban G. (Universidad Nacional de San Luis) ;
Kerr, Suzi (Environmental Defense Fund) ;
Kuemmerle, Tobias (Humboldt-Universität zu Berlin) ;
Lambin, Eric F. (Stanford University) ;
Lavorel, Sandra (Université Grenoble Alpes) ;
Lele, Sharachandra (Indian Institute of Science Education & Research) ;
Mertz, Ole (University of Copenhagen) ;
Messerli, Peter (University of Bern) ;
Metternicht, Graciela (University of New South Wales) ;
Munroe, Darla K. (Ohio State University. Department of Geography) ;
Nagendra, Harini (Azim Premji University) ;
Nielsen, Jonas Østergaard (Humboldt-Universität zu Berlin) ;
Ojima, Dennis S. (Colorado State University) ;
Parker, Dawn Cassandra (University of Waterloo) ;
Pascual, Unai 1973- (Basque Foundation for Science) ;
Porter, John R. (University of Copenhagen) ;
Ramankutty, Navin (University of British Columbia) ;
Reenberg, Anette (University of Copenhagen) ;
Roy Chowdhury, Rinku (Clark University) ;
Seto, Karen C. (Yale University) ;
Seufert, Verena (University of Hohenheim) ;
Shibata, Hideaki (Hokkaido University) ;
Thomson, Allison (The Alliance for Sustainable Agriculture) ;
Turner, Billie L. (Arizona State University) ;
Urabe, Jotaro (Tohoku University) ;
Veldkamp, Tom (University of Twente) ;
Verburg, Peter H. (Vrije Universiteit Amsterdam) ;
Zeleke, Gete (Addis Ababa University) ;
zu Ermgassen, Erasmus K. H. J. (Fonds de la Recherche Scientifique) ;
Universitat Autònoma de Barcelona.
Departament de Geografia
Land use is central to addressing sustainability issues, including biodiversity conservation, climate change, food security, poverty alleviation, and sustainable energy. In this paper, we synthesize knowledge accumulated in land system science, the integrated study of terrestrial social-ecological systems, into 10 hard truths that have strong, general, empirical support. [...]
2022 - 10.1073/pnas.2109217118
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Issue 7 (February 2022) , art. e2109217118
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14 p, 516.6 KB |
Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies
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Lord, Phillip (Newcastle University. School of Computing Science) ;
Spiering, Rachel (Newcastle University. Institute of Cellular Medicine) ;
Aguillon, Juan C. (Universidad de Chile. Instituto de Ciencias Biomédicas (ICBM)) ;
Anderson, Amy E. (Newcastle University. Institute of Cellular Medicine) ;
Appel, Silke (University of Bergen. Broegelmann Research Laboratory) ;
Benítez Ribas, Daniel (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Brinke, Anja ten (Sanquin Research (Amsterdam)) ;
Broere, Femke (Utrecht University) ;
Cools, Nathalie (University of Antwerp. Vaccine & Infectious Disease Institute) ;
Cuturi, Maria Cristina (Center for Research in Transplantation and Immunology (Nantes, França)) ;
Diboll, Julie (Newcastle University. Institute of Cellular Medicine) ;
Geissler, Edward K. (University Hospital Regensburg. Department of Surgery) ;
Giannoukakis, Nick (Institute of Cellular Therapeutics (Pittsburgh, Estats Units d'Amèrica)) ;
Gregori, Silvia (San Raffaele Telethon Institute for Gene Therapy (Milà, Itàlia)) ;
Ham, S. Marieke van (Sanquin Research (Amsterdam)) ;
Lattimer, Staci (Newcastle University. School of Computing Science) ;
Marshall, Lindsay (Newcastle University. School of Computing Science) ;
Harry, Rachel A. (Newcastle University. Institute of Cellular Medicine) ;
Hutchinson, James A. (University Hospital Regensburg. Department of Surgery) ;
Isaacs, John D. (Newcastle University. Institute of Cellular Medicine) ;
Joosten, Irma (Radboud University Medical Centre) ;
Kooten, Cees van (Leiden University Medical Centre) ;
López Díaz de Cerio, Ascensión (Clínica Universidad de Navarra) ;
Nikolic, Tatjana (Leiden University Medical Centre) ;
Oral, Haluk Barbaros (Uludag University. Faculty of Medicine) ;
Sofronic Milosavljevic, Ljiljana (University of Belgrade. Institute for the Application of Nuclear Energy) ;
Ritter, Thomas (National University of Ireland) ;
Riquelme, Paloma (University Hospital Regensburg. Department of Surgery) ;
Thomson, Angus W. (University of Pittsburgh School of Medicine) ;
Trucco, Massimo (Institute of Cellular Therapeutics (Pittsburgh, Estats Units d'Amèrica)) ;
Vives Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hilkens, Catharien M. U. (Newcastle University. Institute of Cellular Medicine)
Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. [...]
2016 - 10.7717/peerj.2300
PeerJ, Vol. 4 (August 2016) , p. e2300
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