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20 p, 786.4 KB |
Associations of modern initial antiretroviral drug regimens with all-cause mortality in adults with HIV in Europe and North America : a cohort study
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Trickey, A. (University of Bristol) ;
Zhang, L. (University of Bristol) ;
Gill, M.J. (University of Calgary) ;
Bonnet, F. (Centre Hospitalier Universitaire de Bordeaux) ;
Burkholder, G. (University of Alabama at Birmingham) ;
Castagna, A. (University vita E Salute) ;
Cavassini, M. (Lausanne University Hospital) ;
Cichon, P. (Otto-Wagner Hospital) ;
Crane, H. (University of Washington) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Grabar, S. (St Antoine Hospital) ;
Guest, J. (Emory University) ;
Obel, N. (Copenhagen University Hospital) ;
Psichogiou, M. (National and Kapodistrian University of Athens) ;
Rava, M. (Instituto de Salud Carlos III) ;
Reiss, P. (Amsterdam Institute for Global Health and Development) ;
Rentsch, C.T. (London School of Hygiene & Tropical Medicine) ;
Riera, M. (Fundación Instituto de Investigación Sanitaria Illes Balears) ;
Schuettfort, G. (Frankfurt University Hospital) ;
Silverberg, M.J. (Kaiser Permanente Northern California) ;
Smith, C. (University College London) ;
Stecher, M. (German Center for Infection Research) ;
Sterling, T.R. (Vanderbilt University School of Medicine) ;
Ingle, S.M. (University of Bristol) ;
Sabin, C.A. (University College London) ;
Sterne, J.A.C. (University of Bristol) ;
Universitat Autònoma de Barcelona
Over the past decade, antiretroviral therapy (ART) regimens that include integrase strand inhibitors (INSTIs) have become the most commonly used for people with HIV starting ART. Although trials and observational studies have compared virological failure on INSTI-based with other regimens, few data are available on mortality in people with HIV treated with INSTIs in routine care. [...]
2022 -  10.1016/S2352-3018(22)00046-7
The lancet. HIV, Vol. 9 Núm. 6 (june 2022) , p. e404-e413
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16 p, 1.2 MB |
Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers
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Chereau, Fanny (Université Paris-Saclay) ;
Madec, Yoann (Institut Pasteur) ;
Sabin, Caroline A (Research Department of Infection and Population Health (Regne Unit)) ;
Obel, Niels (Copenhagen University Hospital Rigshospitalet) ;
Ruiz-Mateos, Ezequiel (Instituto de Biomedicina de Sevilla) ;
Chrysos, Georgios (Tzaneio General Hospital of Piraeus) ;
Fidler, Sarah (Imperial College (Regne Unit)) ;
Lehmann, Clara (University of Cologne and German Center for Infection Research) ;
Zangerle, Robert (DMedical University Innsbruck) ;
Wittkop, Linda (University Bordeaux) ;
Reiss, Peter (Stichting HIV Monitoring) ;
Hamouda, Osamah (Robert Koch Institute) ;
Estrada Perez, Vicente (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Leal, Manuel (Instituto de Biomedicina de Sevilla) ;
Mocroft, Amanda (Research Department of Infection and Population Health (Regne Unit)) ;
García de Olalla, Patricia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Ammassari, Adriana (Istituto Nazionale Malattie Infettive) ;
D'Arminio Monforte, Antonella (University Hospital (Itàlia)) ;
Mussini, Cristina (University of Modena and Reggio Emilia) ;
Segura, Ferran (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Castagna, Antonella (San Raffaele Vita Salute University) ;
Cavassini, Matthias (Lausanne University Hospital) ;
Grabar, Sophie (Institut Pierre Louis d'Epidémiologie et de Santé Publique) ;
Morlat, Philippe (Université de Bordeaux) ;
De Wit, Stéphane (Université Libre de Bruxelles) ;
Lambotte, Olivier (Université Paris Sud) ;
Meyer, Laurence (Université Paris-Saclay) ;
Universitat Autònoma de Barcelona
HIV controllers (HICs) spontaneously maintain HIV viral replication at low level without antiretroviral therapy (ART), a small number of whom will eventually lose this ability to control HIV viremia. [...]
2017 - 10.1371/journal.pone.0173893
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10 p, 757.2 KB |
Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males
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Baldassarri, Margherita (University of Siena. Department of Medical Biotechnologies) ;
Picchiotti, Nicola (University of Pavia. Department of Mathematics) ;
Fava, Francesca (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ;
Fallerini, Chiara (University of Siena. Department of Medical Biotechnologies) ;
Benetti, Elisa (University of Siena. Department of Medical Biotechnologies) ;
Daga, Sergio (University of Siena. Department of Medical Biotechnologies) ;
Valentino, Floriana (University of Siena. Department of Medical Biotechnologies) ;
Doddato, Gabriella (University of Siena. Department of Medical Biotechnologies) ;
Furini, Simone (University of Siena. Department of Medical Biotechnologies) ;
Giliberti, Annarita (University of Siena. Department of Medical Biotechnologies) ;
Tita, Rossella (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ;
Amitrano, Sara (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ;
Bruttini, Mirella (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ;
Croci, Susanna (University of Siena. Department of Medical Biotechnologies) ;
Meloni, Ilaria (University of Siena. Department of Medical Biotechnologies) ;
Pinto, Anna Maria (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ;
Iuso, Nicola (University of Siena. Department of Medical Biotechnologies) ;
Gabbi, Chiara ;
Sciarra, Francesca (Sapienza University of Rome. Department of Experimental Medicine) ;
Venneri, Mary Anna (Sapienza University of Rome. Department of Experimental Medicine) ;
Gori, Marco (Université Côte d'Azur) ;
Sanarico, Maurizio ;
Crawley, Francis P. (Good Clinical Practice Alliance-Europe (GCPA) and Strategic Initiative for Developing Capacity in Ethical Review-Europe (SIDCER) (Leuven, Bèlgica)) ;
Pagotto, Uberto (University of Bologna. Department of Medical and Surgical Sciences) ;
Fanelli, Flaminia (University of Bologna. Department of Medical and Surgical Sciences) ;
Mezzullo, Marco (University of Bologna. Department of Medical and Surgical Sciences) ;
Domínguez-Garrido, Elena (Fundación Rioja Salud. Molecular Diagnostic Unit) ;
Planas-Serra, Laura (Spanish Covid HGE) ;
Schlüter, Agatha (Spanish Covid HGE) ;
Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lapunzina, Pablo (Hospital Universitario La Paz (Madrid)) ;
Tenorio, Jair (Hospital Universitario La Paz (Madrid)) ;
Pujol, Aurora 1968- (Institució Catalana de Recerca i Estudis Avançats) ;
Castagna, Maria Grazia (University of Siena. Department of Medical, Surgical and Neurological Sciences) ;
Marcelli, Marco (Baylor College of Medicine (Houston, Estats Units d'Amèrica). Department of Medicine) ;
Isidori, Andrea M. (Sapienza University of Rome. Department of Experimental Medicine) ;
Renieri, Alessandra (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ;
Frullanti, Elisa (University of Siena. Department of Medical, Surgical and Neurological Sciences) ;
Mari, Francesca (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ;
Universitat Autònoma de Barcelona
While SARS-CoV-2 similarly infects men and women, COVID-19 outcome is less favorable in men. Variability in COVID-19 severity may be explained by differences in the host genome. We compared poly-amino acids variability from WES data in severely affected COVID-19 patients versus SARS-CoV-2 PCR-positive oligo-asymptomatic subjects. [...]
2021 - 10.1016/j.ebiom.2021.103246
EBioMedicine, Vol. 65 (february 2021) , p. 103246
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13 p, 1.0 MB |
Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia : A comparative study of the ALWP EBMT
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Sanz, Jaime (Centro de Investigación Biomédica en Red de Cáncer) ;
Galimard, J. E. (EBMT Paris Office. Hospital Saint Antoine) ;
Labopin, Myriam (Department of Hematology. Hopital Saint Antoine. Sorbonne University) ;
Afanasyev, B. (First State Pavlov Medical University of St. Petersburg. Raisa Gorbacheva Mem. Research Institute for Paediatric Oncology. Hematology. and Transplantation) ;
Angelucci, Emanuele (Department of Haematology. IRCCS Ospedale Policlinico San Martino) ;
Ciceri, Fabio (Haematology and BMT) ;
Blaise, Didier (Programme de Transplantation and Therapie Cellulaire. Centre de Recherche en Cancérologie de Marseille. Institut Paoli Calmettes) ;
Cornelissen, J. J. (Department of Hematology. Erasmus MC Cancer Institute. University Medical Center Rotterdam) ;
Meijer, E. (Department of Hematology (Br 250). VU University Medical Center) ;
Diez-Martin, J. L. (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Koc, Y. (Stem Cell Transplant Unit. Medical Park Hospitals) ;
Rovira Tarrats, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Castagna, L. (Transplantation Unit. Department of Oncology and Haematology. Istituto Clinico Humanitas) ;
Savani, B. N. (Vanderbilt University Medical Center) ;
Ruggeri, Annalisa (Ospedale Pediatrico Bambino Gesù (Roma, Itàlia)) ;
Nagler, Arnon (ALWP of the EBMT Office. Saint Antoine Hospital) ;
Mohty, Mohamad (Department of Hematology. Hopital Saint Antoine. Sorbonne University) ;
Universitat Autònoma de Barcelona
Background: The use of post-transplant cyclophosphamide (PTCy) is highly effective in preventing graft-versus-host disease (GVHD) in the haploidentical (Haplo) transplant setting and is being increasingly used in matched sibling (MSD) and matched unrelated (MUD) transplants. [...]
2020 - 10.1186/s13045-020-00882-6
Journal of hematology & oncology, Vol. 13 Núm. 1 (june 2020) , p. 46
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