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13 p, 765.7 KB |
Male breast cancer in BRCA1 and BRCA2 mutation carriers : pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
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Silvestri, Valentina (Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy) ;
Barrowdale, Daniel (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Mulligan, Anna Marie (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON Canada) ;
Neuhausen, Susan L. (Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA USA) ;
Fox, Stephen (Peter MacCallum Cancer Institute, East Melbourne, Australia) ;
Karlan, Beth Y. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ;
Mitchell, Gillian (Department of Oncology, The University of Melbourne, Melbourne, VIC Australia) ;
James, Paul (Department of Oncology, The University of Melbourne, Melbourne, VIC Australia) ;
Thull, Darcy L. (University of Pittsburgh School of Medicine, Pittsburgh, PA USA) ;
Zorn, Kristin K. (University of Pittsburgh School of Medicine, Pittsburgh, PA USA) ;
Carter, Natalie J. (UPMC Cancer Center, Pittsburgh, PA USA) ;
Nathanson, Katherine L. (Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA USA) ;
Domchek, Susan M. (Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA USA) ;
Rebbeck, Timothy R. (Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA) ;
Ramus, Susan J. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA USA) ;
Nussbaum, Robert L. (Department of Medicine and Genetics, University of California, San Francisco, San Francisco, CA USA) ;
Olopade, Olufunmilayo I. (Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, IL USA) ;
Rantala, Johanna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Yoon, Sook-Yee (University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia) ;
Caligo, Maria (University Hospital of Pisa (Pisa, Itàlia)) ;
Spugnesi, Laura (University Hospital of Pisa (Pisa, Itàlia)) ;
Bojesen, Anders (Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark) ;
Pedersen, Inge Sokilde (Aalborg University Hospital (Dinamarca)) ;
Thomassen, Mads (Odense University Hospital (Dinamarca)) ;
Jensen, Uffe Birk (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Toland, Amanda Ewart (Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, The Ohio State University, Columbus, OH USA) ;
Senter, Leigha (Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, OH USA) ;
Andrulis, Irene L. (Department of Molecular Genetics, University of Toronto, Toronto, ON Canada) ;
Glendon, Gord (Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON Canada) ;
Hulick, Peter J. (Center for Medical Genetics, North Shore University Health System, Evanston, IL USA) ;
Imyanitov, Evgeny N. (N.N. Petrov Institute of Oncology, St. Petersburg, Russia) ;
Greene, Mark H. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD USA) ;
Mai, Phuong L. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD USA) ;
Singer, Christian F. (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Rappaport-Fuerhauser, Christine (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Kramer, Gero (Department of Urology, Medical University of Vienna, Vienna, Austria) ;
Vijai, Joseph (Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY USA) ;
Offit, Kenneth (Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY USA) ;
Robson, Mark (Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY USA) ;
Lincoln, Anne (Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY USA) ;
Jacobs, Lauren (Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY USA) ;
Machackova, Eva (Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic) ;
Foretova, Lenka (Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno, Czech Republic) ;
Navratilova, Marie (Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic) ;
Vasickova, Petra (Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic) ;
Couch, Fergus J. (Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA) ;
Hallberg, Emily (Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA) ;
Ruddy, Kathryn J. (Department of Oncology, Mayo Clinic, Rochester, MN USA) ;
Sharma, Priyanka (Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, KS USA) ;
Kim, Sung-Won (Department of Surgery, Daerim St. Mary's Hospital, Seoul, Korea) ;
Teixeira, Manuel R. (Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal) ;
Pinto, Pedro (Department of Genetics, Portuguese Institute of Oncology, Porto, Portugal) ;
Montagna, Marco (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Matricardi, Laura (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Arason, Adalgeir (Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik, Iceland) ;
Johannsson, Oskar Th (Landspitali University Hospital (Reykjavík, Islàndia)) ;
Barkardottir, Rosa B. (Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik, Iceland) ;
Jakubowska, Anna (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ;
Lubinski, Jan (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ;
Izquierdo, Angel (Institut Català d'Oncologia) ;
Pujana, Miguel Angel (Institut d'Investigació Biomèdica de Bellvitge) ;
Balmaña Gelpí, Judith (Vall d'Hebron Institut d'Oncologia) ;
Diez, Orland (Vall d'Hebron Institut d'Oncologia) ;
Ivady, Gabriella (Department of Pathology, National Institute of Oncology, Budapest, Hungary) ;
Papp, Janos (Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary) ;
Olah, Edith (Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary) ;
Kwong, Ava (Department of Surgery, The University of Hong Kong, Hong Kong, China) ;
Nevanlinna, Heli (Helsinki University Hospital (Finlàndia)) ;
Aittomäki, Kristiina (Helsinki University Hospital (Finlàndia)) ;
Pérez-Segura, Pedro (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Caldes, Trinidad (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Van Maerken, Tom (Center for Medical Genetics, Ghent University, Ghent, Belgium) ;
Poppe, Bruce (Center for Medical Genetics, Ghent University, Ghent, Belgium) ;
Claes, Kathleen (Center for Medical Genetics, Ghent University, Ghent, Belgium) ;
Isaacs, Claudine (Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA) ;
Elan, Camille (Department of Tumour Biology, Institut Curie, Paris, France) ;
Lasset, Christine (Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France) ;
Stoppa-Lyonnet, Dominique (Université Paris Descartes, Sorbonne Paris Cité, Paris, France) ;
Barjhoux, Laure (INSERM U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Université Lyon, Lyon, France) ;
Belotti, Muriel (Department of Tumour Biology, Institut Curie, Paris, France) ;
Meindl, Alfons (Department of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany) ;
Gehrig, Andrea (Institute of Human Genetics, University of Wurzburg, Wurzburg, Germany) ;
Sutter, Christian (Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany) ;
Engel, Christoph (Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig, Germany) ;
Niederacher, Dieter (University of Dusseldorf, Dusseldorf, Germany) ;
Steinemann, Doris (Hannover Medical School, Hannover, Germany) ;
Hahnen, Eric (Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany) ;
Kast, Karin (Department of Gynecology and Obstetrics, Technical University of Dresden, Dresden, Germany) ;
Arnold, Norbert (Department of Gynaecolgy and Obstetrics, University Hospital of Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany) ;
Varon-Mateeva, Raymonda (Institute of Human Genetics, Charité, Berlin, Germany) ;
Wand, Dorothea (Institute of Human Genetics, Leipzig, Germany) ;
Godwin, Andrew K. (Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS USA) ;
Evans, Gareth (Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK) ;
Frost, Debra (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Perkins, Jo (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Adlard, Julian (Yorkshire Regional Genetics Service, Leeds, UK) ;
Izatt, Louise (Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, UK) ;
Platte, Radka (Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK) ;
Eeles, Ros (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Ellis, Steve (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Hamann, Ute (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Garber, Judy (Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA USA) ;
Fostira, Florentia (Molecular Diagnostics Laboratory, Institute of Nuclear and Radiological Sciences and Technology (INRASTES), National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece) ;
Fountzilas, George (Department of Medical Oncology, Papageorgiou Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece) ;
Pasini, Barbara (AO Città della Salute e della Scienza, Turin, Italy) ;
Giannini, Giuseppe (Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy) ;
Rizzolo, Piera (Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy) ;
Russo, Antonio (Section of Medical Oncology, Department of Surgical and Oncological Sciences, University of Palermo, Palermo, Italy) ;
Cortesi, Laura (Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy) ;
Papi, Laura (Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy) ;
Varesco, Liliana (Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Scientific Institute of Hospitalization and Care), AOU San Martino - IST National Institute for Cancer Research, Genoa, Italy) ;
Palli, Domenico (Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy) ;
Zanna, Ines (Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy) ;
Savarese, Antonella (Unit of Genetic Counselling, Medical Oncology Department, Regina Elena National Cancer Institute, Rome, Italy) ;
Radice, Paolo (Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), 20133 Milan, Italy) ;
Manoukian, Siranoush (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan, Italy) ;
Peissel, Bernard (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan, Italy) ;
Barile, Monica (Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan, Italy) ;
Bonanni, Bernardo (Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan, Italy) ;
Viel, Alessandra (Division of Experimental Oncology, CRO Aviano National Cancer Institute, Aviano, PN Italy) ;
Pensotti, Valeria (Cogentech Cancer Genetic Test Laboratory, Milan, Italy) ;
Tommasi, Stefania (National Cancer Institute "Giovanni Paolo II", Bari, Italy) ;
Peterlongo, Paolo (IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy) ;
Weitzel, Jeffrey N. (Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, CA USA) ;
Osorio, Ana (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Benitez, Javier (Centro Nacional de Investigaciones Oncológicas) ;
McGuffog, Lesley (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Healey, Sue (Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia) ;
Gerdes, Anne-Marie (Copenhagen University Hospital Rigshospitalet) ;
Ejlertsen, Bent (Copenhagen University Hospital Rigshospitalet) ;
Hansen, Thomas V. O. (Copenhagen University Hospital Rigshospitalet) ;
Steele, Linda (Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA USA) ;
Ding, Yuan Chun (Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA USA) ;
Tung, Nadine (Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA USA) ;
Janavicius, Ramunas (State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania) ;
Goldgar, David E. (Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT USA) ;
Buys, Saundra (Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT USA) ;
Daly, Mary B. (Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA USA) ;
Bane, Anita (Department of Pathology & Molecular Medicine, Juravinski Hospital and Cancer Centre, McMaster University, Hamilton, ON Canada) ;
Terry, Mary Beth (Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY USA) ;
John, Esther M. (Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA USA) ;
Southey, Melissa (Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia) ;
Easton, Douglas F. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Chenevix-Trench, Georgia (Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia) ;
Antoniou, Antonis C. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Ottini, Laura (Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy) ;
Universitat Autònoma de Barcelona
BRCA1 and, more commonly, BRCA2 mutations are associated with increased risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of breast cancers (BCs) in men with BRCA1/2 mutations. [...]
2016 -  10.1186/s13058-016-0671-y
Breast cancer research, Vol. 18 (february 2016)
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17 p, 277.3 KB |
The Influence of Hormonal Factors on the Risk of Developing Cervical Cancer and Pre-Cancer : results from the EPIC Cohort
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Roura, Esther (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Travier, Noémie (Institut Català d'Oncologia) ;
Waterboer, Tim (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
De Sanjose, Silvia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Bosch José, Francesc Xavier 1947- (Institut Català d'Oncologia) ;
Pawlita, Michael (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Pala, Valeria (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy) ;
Weiderpass, Elisabete (Folkhälsan Research Center, Helsinki, Finland) ;
Margall, Núria (Institut d'Investigació Biomèdica Sant Pau) ;
Dillner, Joakim (Karolinska Institutet (Estocolm, Suècia)) ;
Gram, Inger T. (UiT The Arctic University of Norway, Tromsø, Norway) ;
Tjønneland, Anne (Danish Cancer Society Research Center, Copenhagen, Denmark) ;
Munk, Christian (Danish Cancer Society Research Center, Copenhagen, Denmark) ;
Palli, Domenico (Cancer Research and Prevention Institute-ISPO, Florence, Italy) ;
Khaw, Kay-Tee (University of Cambridge) ;
Overvad, Kim (Aarhus University, Aarhus, Denmark) ;
Clavel-Chapelon, Françoise (Institut Gustave Roussy (Villejuif, França)) ;
Mesrine, Sylvie (Institut Gustave Roussy (Villejuif, França)) ;
Fournier, Agnès (Institut Gustave Roussy (Villejuif, França)) ;
Fortner, Renée T. (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Ose, Jennifer (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Steffen, Annika (German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany) ;
Trichopoulou, Antonia (Hellenic Health Foundation, Athens, Greece) ;
Lagiou, Pagona (Harvard School of Public Health, Boston, United States of America) ;
Orfanos, Philippos (University of Athens Medical School, Athens, Greece) ;
Masala, Giovanna (Cancer Research and Prevention Institute-ISPO, Florence, Italy) ;
Tumino, Rosario ("Civic-M.P. Arezzo" Hospital, Ragusa, Italy) ;
Sacerdote, Carlotta (Centre for Cancer Epidemiology and Prevention (CPO Piemonte), Turin, Italy) ;
Polidoro, Silvia (Human Genetics Foundation (HuGeF), Turin, Italy) ;
Mattiello, Amalia (Federico II University, Naples, Italy) ;
Lund, Eiliv (UiT The Arctic University of Norway, Tromsø, Norway) ;
Peeters, Petra H. (University Medical Center Utrecht, Utrecht, The Netherlands) ;
Bueno-de-Mesquita, H. Bas (University of Malaya, Kuala Lumpur, Malaysia) ;
Quirós, J. Ramón (Dirección de Salud Pública de Asturias) ;
Sánchez, María-José (Instituto de Investigación Sanitaria de Granada) ;
Navarro Sánchez, Carmen (Universidad de Murcia) ;
Barricarte, Aurelio (Instituto de Investigación Sanitaria de Navarra) ;
Larrañaga, Nerea (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Ekström, Johanna (Lund University, Medicon Village, Lund, Sweden) ;
Lindquist, David (Department of Radiation Sciences, Umeå University, Umeå, Sweden) ;
Idahl, Annika (Umeå University, Umeå, Sweden) ;
Travis, Ruth C. (University of Oxford, Oxford, United Kingdom) ;
Merritt, Melissa A. (Imperial College London, London, United Kingdom) ;
Gunter, Marc J. (Imperial College London, London, United Kingdom) ;
Rinaldi, Sabina (International Agency for Research on Cancer, Lyon, France) ;
Tommasino, Massimo (International Agency for Research on Cancer, Lyon, France) ;
Franceschi, Silvia (International Agency for Research on Cancer, Lyon, France) ;
Riboli, Elio (Imperial College London, London, United Kingdom) ;
Castellsagué, Xavier (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Universitat Autònoma de Barcelona
In addition to HPV, high parity and hormonal contraceptives have been associated with cervical cancer (CC). However, most of the evidence comes from retrospective case-control studies. The aim of this study is to prospectively evaluate associations between hormonal factors and risk of developing cervical intraepithelial neoplasia grade 3 (CIN3)/carcinoma in situ (CIS) and invasive cervical cancer (ICC). [...]
2016 - 10.1371/journal.pone.0147029
PloS one, Vol. 11 (january 2016)
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