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12 p, 1.2 MB |
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis
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Gao, Yixin (Xuzhou Medical University) ;
Wang, Ting (Xuzhou Medical University) ;
Yu, Xinghao (Xuzhou Medical University) ;
Ferrari, Raffaele (Russell Square House) ;
Hernandez, Dena G. (Queen Square) ;
Nalls, Michael A. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ;
Rohrer, Jonathan D. (Queen Square) ;
Ramasamy, Adaikalavan (University of Oxford) ;
Kwok, John B.J. (University of New South Wales) ;
Dobson-Stone, Carol (University of New South Wales) ;
Brooks, William S. (University of New South Wales) ;
Schofield, Peter R. (Neuroscience Research Australia) ;
Halliday, Glenda M. (Neuroscience Research Australia) ;
Hodges, John R. (Neuroscience Research Australia) ;
Piguet, Olivier (Neuroscience Research Australia) ;
Bartley, Lauren (Neuroscience Research Australia) ;
Thompson, Elizabeth (University of Adelaide) ;
Haan, Eric (University of Adelaide) ;
Hernández, Isabel (Institut Català de Neurociéncies Aplicades) ;
Ruiz, Agustín (Institut Català de Neurociéncies Aplicades) ;
Boada, Mercè (Institut Català de Neurociéncies Aplicades) ;
Borroni, Barbara (University of Brescia) ;
Padovani, Alessandro (University of Brescia) ;
Cruchaga, Carlos (Washington University School of Medicine) ;
Cairns, Nigel J. (Washington University) ;
Benussi, Luisa (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Binetti, Giuliano (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Ghidoni, Roberta (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Forloni, Gianluigi (IRCCS Istituto di Ricerche Farmacologiche. "Mario Negri") ;
Albani, Diego (IRCCS Istituto di Ricerche Farmacologiche. "Mario Negri") ;
Galimberti, Daniela (IRCCS Ospedale Maggiore Policlinico) ;
Fenoglio, Chiara (IRCCS Ospedale Maggiore Policlinico) ;
Serpente, Maria (IRCCS Ospedale Maggiore Policlinico) ;
Scarpini, Elio (University of Milan) ;
Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Waldö, Maria Landqvist (Lund University) ;
Nilsson, Karin (Lund University) ;
Nilsson, Christer (Lund University) ;
Mackenzie, Ian R.A. (University of British Columbia) ;
Hsiung, Ging-Yuek R. (University of British Columbia) ;
Mann, David M. A. (Salford Royal Hospital) ;
Grafman, Jordan (Northwestern University) ;
Morris, Christopher M. (Newcastle University) ;
Attems, Johannes (Newcastle University) ;
Griffiths, Timothy D. (Newcastle University Medical School) ;
McKeith, Ian G. (Newcastle University) ;
Thomas, Alan J. (Newcastle University) ;
Pietrini, Pietro (IMT School for Advanced Studies) ;
Huey, Edward D. (Columbia University) ;
Wassermann, Eric M. (National Insititutes of Health) ;
Baborie, Atik (University of Alberta Edmonton) ;
Jaros, Evelyn (Newcastle University) ;
Tierney, Michael C. (National Insititutes of Health) ;
Pastor, Pau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Razquin, Cristina (Universidad de Navarra) ;
Ortega-Cubero, Sara (Universidad de Navarra) ;
Alonso, Elena (Universidad de Navarra) ;
Perneczky, Robert (West London Mental Health Trust) ;
Diehl-Schmid, Janine (Technische Universität München) ;
Alexopoulos, Panagiotis (Technische Universität München) ;
Kurz, Alexander (Technische Universität München) ;
Rainero, Innocenzo (A.O. Città della Salute e della Scienza di Torino) ;
Rubino, Elisa (A.O. Città della Salute e della Scienza di Torino) ;
Pinessi, Lorenzo (A.O. Città della Salute e della Scienza di Torino) ;
Rogaeva, Ekaterina (University of Toronto) ;
St George Hyslop, Peter (University of Cambridge) ;
Rossi, Giacomina (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Tagliavini, Fabrizio (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Giaccone, Giorgio (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Rowe, James B. (Behavioural and Clinical Neuroscience Institute) ;
Schlachetzki, Johannes C. M. (University of California San Diego) ;
Uphill, James (University College London. Institute of Neurology) ;
Collinge, John (University College London. Institute of Neurology) ;
Mead, Simon (University College London. Institute of Neurology) ;
Danek, Adrian (German Center for Neurodegenerative Diseases (DZNE)) ;
Van Deerlin, Vivianna M. (University of Pennsylvania Perelman School of Medicine) ;
Grossman, Murray (University of Pennsylvania Perelman School of Medicine) ;
Trojanowski, John Q. (University of Pennsylvania Perelman School of Medicine) ;
van der Zee, Julie (University of Antwerp) ;
Cruts, Marc (University of Antwerp) ;
Van Broeckhoven, Christine (University of Antwerp) ;
Cappa, Stefano F. (Vita-Salute University and San Raffaele Scientific Institute) ;
Leber, Isabelle (CNRS UMR 7225) ;
Hannequin, Didier (Rouen University Hospital (França)) ;
Golfier, Véronique (CH Saint Brieuc) ;
Vercelletto, Martine (CHU Nantes) ;
Brice, Alexis (AP-HP. Hôpital de la Salpêtrière) ;
Nacmias, Benedetta (University of Florence) ;
Sorbi, Sandro (University of Florence and IRCCS "Don Carlo Gnocchi" Firenze) ;
Bagnoli, Silvia (University of Florence) ;
Piaceri, Irene (University of Florence) ;
Nielsen, Jørgen E. (Copenhagen University Hospital) ;
Hjermind, Lena E. (University of Copenhagen) ;
Riemenschneider, Matthias (Saarland University) ;
Mayhaus, Manuel (Saarland University) ;
Ibach, Bernd (University Regensburg) ;
Gasparoni, Gilles (Saarland University) ;
Pichler, Sabrina (Saarland University) ;
Gu, Wei (University of Luxembourg) ;
Rossor, Martin N. (Queen Square) ;
Fox, Nick C. (University College London Queen Square Institute of Neurology. Dementia Research Centre) ;
Warren, Jason D. (Queen Square) ;
Spillantini, Maria Grazia (University of Cambridge) ;
Morris, Huw R. (Russell Square House) ;
Rizzu, Patrizia (German Center for Neurodegenerative Diseases-Tübingen) ;
Heutink, Peter (German Center for Neurodegenerative Diseases-Tübingen) ;
Snowden, Julie S. (University of Manchester) ;
Rollinson, Sara (University of Manchester) ;
Richardson, Anna (University of Manchester) ;
Gerhard, Alexander (The University of Manchester) ;
Bruni, Amalia C. (ASPCZ) ;
Maletta, Raffaele (ASPCZ) ;
Frangipane, Francesca (ASPCZ) ;
Cupidi, Chiara (ASPCZ) ;
Bernardi, Livia (ASPCZ) ;
Anfossi, Maria (ASPCZ) ;
Gallo, Maura (ASPCZ) ;
Conidi, Maria Elena (ASPCZ) ;
Smirne, Nicoletta (ASPCZ) ;
Rademakers, Rosa (Mayo Clinic Jacksonville) ;
Baker, Matt (Mayo Clinic Jacksonville) ;
Dickson, Dennis W. (Mayo Clinic Jacksonville) ;
Graff-Radford, Neill R. (Mayo Clinic Jacksonville) ;
Petersen, Ronald C. (Mayo Clinic Rochester) ;
Knopman, David (Mayo Clinic Rochester) ;
Josephs, Keith A. (Mayo Clinic Rochester) ;
Boeve, Bradley (Mayo Clinic Rochester) ;
Parisi, Joseph E. (Mayo Clinic Rochester) ;
Seeley, William W. (University of California) ;
Miller, Bruce L. (University of California) ;
Karydas, Anna M. (University of California) ;
Rosen, Howard (University of California) ;
van Swieten, John C. (VU University Medical Centre) ;
Dopper, Elise G. P. (Erasmus Medical Centre) ;
Seelaar, Harro (Erasmus Medical Centre) ;
Pijnenburg, Yolande A. L. (VU University Medical Centre) ;
Scheltens, Philip (VU University Medical Centre) ;
Logroscino, Giancarlo (University of Bari) ;
Capozzo, Rosa (University of Bari) ;
Novelli, Valeria (Fondazione Policlinico Universitario A. Gemelli) ;
Puca, Annibale A. (University of Salerno) ;
Franceschi, Massimo (IRCCS Multimedica) ;
Postiglione, Alfredo (University of Naples Federico II) ;
Milan, Graziella (Geriatric Center Frullone- ASL Napoli 1 Centro) ;
Sorrentino, Paolo (Geriatric Center Frullone- ASL Napoli 1 Centro) ;
Kristiansen, Mark (Institute of Child Health (ICH)) ;
Chiang, Huei-Hsin (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Graff, Caroline (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Pasquier, Florence (Univ Lille) ;
Rollin, Adeline (Univ Lille) ;
Deramecourt, Vincent (Univ Lille) ;
Lebouvier, Thibaud (Univ Lille) ;
Kapogiannis, Dimitrios (National Institute on Aging (NIA/NIH)) ;
Ferrucci, Luigi (National Institute on Aging (Baltimore, Estats Units d'Amèrica)) ;
Pickering-Brown, S. (University of Manchester) ;
Singleton, Andrew B. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ;
Hardy, John (Russell Square House) ;
Momeni, Parastoo (Texas Tech University Health Science Center) ;
Zhao, Huashuo (Xuzhou Medical University) ;
Zeng, Ping (Xuzhou Medical University) ;
Universitat Autònoma de Barcelona
We employed Mendelian randomization (MR) to evaluate the causal relationship between leukocyte telomere length (LTL) and amyotrophic lateral sclerosis (ALS) with summary statistics from genome-wide association studies (n = ~ 38,000 for LTL and ~ 81,000 for ALS in the European population; n = ~ 23,000 for LTL and ~ 4,100 for ALS in the Asian population). [...]
2020 -  10.1038/s41598-020-68848-9
Scientific reports, Vol. 10 Núm. 1 (january 2020) , p. 12184
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13 p, 3.8 MB |
Cortical microstructure in primary progressive aphasia : a multicenter study
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Borrego-Écija, Sergi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Mandelli, Maria Luisa (University of California. Memory and Aging Center) ;
Falgàs, Neus (University of California. Memory and Aging Center) ;
Welch, Ariane E. (University of California. Memory and Aging Center) ;
Pegueroles, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Santos-Santos, Miguel Angel (Institut d'Investigació Biomèdica Sant Pau) ;
Bejanin, Alexandre (Institut d'Investigació Biomèdica Sant Pau) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Belbin, Olivia (Institut d'Investigació Biomèdica Sant Pau) ;
Sánchez-Saudinós, María Belén (Institut d'Investigació Biomèdica Sant Pau) ;
Bargalló, Núria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
González-Ortiz, Sofía (Hospital del Mar (Barcelona, Catalunya)) ;
Lladó, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Blesa, Rafael (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Dickerson, Bradford C. (Massachusetts Alzheimer's Disease Research Center) ;
Rosen, Howard J. (University of California. Memory and Aging Center) ;
Miller, Bruce L. (University of California, San Francisco (UCSF)) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Gorno-Tempini, Maria Luisa (University of California. Department of Neurology) ;
Sanchez-Valle, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau)
Background: Cortical mean diffusivity is a novel imaging metric sensitive to early changes in neurodegenerative syndromes. Higher cortical mean diffusivity values reflect microstructural disorganization and have been proposed as a sensitive biomarker that might antedate macroscopic cortical changes. [...]
2022 - 10.1186/s13195-022-00974-0
Alzheimer's research & therapy, Vol. 14 Núm. 1 (december 2022) , p. 27
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16 p, 2.1 MB |
Diagnostic Accuracy of Magnetic Resonance Imaging Measures of Brain Atrophy Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Degeneration
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Nigro, Salvatore (Institute of Nanotechnology. National Research Council) ;
Vandevrede, Lawren (Memory and Aging Center. Department of Neurology. University of California) ;
Falgàs, Neus (Memory and Aging Center. Department of Neurology. University of California) ;
Heuer, Hilary W. (Memory and Aging Center. Department of Neurology. University of California) ;
Painous, Cèlia (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Compta, Yaroslau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Martí, Maria J. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Logroscino, Giancarlo (Department of Basic Medicine. Neuroscience. and Sense Organs. University of Bari Aldo Moro) ;
Quattrone, Andrea (Neuroimaging Research Unit. Institute of Molecular Bioimaging and Physiology. National Research Council) ;
Perry, David C. (Memory and Aging Center. Department of Neurology. University of California) ;
Gorno-Tempini, Maria Luisa (Memory and Aging Center. Department of Neurology. University of California) ;
Rosen, Howard J. (Memory and Aging Center. Department of Neurology. University of California) ;
Grinberg, Lea T. (Memory and Aging Center. Department of Neurology. University of California) ;
Spina, Salvatore (Memory and Aging Center. Department of Neurology. University of California) ;
La Joie, Renaud (Memory and Aging Center. Department of Neurology. University of California) ;
Rabinovici, Gil D. (Memory and Aging Center. Department of Neurology. University of California) ;
Miller, Bruce L. (University of California, San Francisco (UCSF)) ;
Rojas, Julio C. (Memory and Aging Center. Department of Neurology. University of California) ;
Seeley, William W. (Memory and Aging Center. Department of Neurology. University of California) ;
Boxer, Adam (Memory and Aging Center. Department of Neurology. University of California) ;
Universitat Autònoma de Barcelona
Importance: The accurate diagnosis of progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) is hampered by imperfect clinical-pathological correlations. Objective: To assess and compare the diagnostic value of the magnetic resonance parkinsonism index (MRPI) and other magnetic resonance imaging-based measures of cerebral atrophy to differentiate between PSP, CBD, and other neurodegenerative diseases. [...]
2022 - 10.1001/jamanetworkopen.2022.9588
JAMA network open, Vol. 5 Núm. 4 (january 2022) , p. E229588
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11 p, 1.6 MB |
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia
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Friedberg, Adit (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Pasquini, Lorenzo (Neuroscape, University of California, San Francisco) ;
Diggs, Ryan (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Glaubitz, Erika A. (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Lopez, Lucia (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Illán-Gala, Ignacio (Institut de Recerca Sant Pau) ;
Iaccarino, Leonardo (now with Eli Lilly and Company, Philadelphia, Pennsylvania) ;
La Joie, Renaud (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Mundada, Nidhi (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Knudtson, Marguerite (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Neylan, Kyra (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Brown, Jesse (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Allen, Isabel (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Rankin, Katherine P. (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Bonham, Luke W. (Department of Radiology and Biomedical Imaging, University of California, San Francisco) ;
Yokoyama, Jennifer S. (Department of Radiology and Biomedical Imaging, University of California, San Francisco) ;
Ramos, Eliana M. (Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles) ;
Geschwind, Daniel H. (Institute for Precision Health, University of California, Los Angeles) ;
Spina, Salvatore (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Grinberg, Lea T. (Department of Pathology, University of California, San Francisco) ;
Miller, Zachary A. (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Kramer, Joel H. (University of California. Department of Neurology) ;
Rosen, Howard (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Gorno-Tempini, Maria Luisa (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Rabinovici, Gil (Associate Editor, JAMA Neurology) ;
Seeley, William W. (Department of Pathology, University of California, San Francisco) ;
Miller, Bruce L. (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Universitat Autònoma de Barcelona
This case-control study assesses the anatomical and physiological underpinnings of visual artistic creativity in individuals with frontotemporal dementia. What are the neural underpinnings of visual artistic creativity (VAC) in the setting of frontotemporal dementia (FTD)? In this study of 119 patients, VAC occurred early in the course of FTD, was disproportionately observed in patients with temporal lobe-predominant degeneration, and may be associated with damage to brain regions that normally suppress dorsomedial occipital cortex function. [...]
2023 - 10.1001/jamaneurol.2023.0001
JAMA Neurology, Vol. 80 (february 2023) , p. 377-387
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15 p, 1.0 MB |
Specific cortical and subcortical grey matter regions are associated with insomnia severity
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Falgàs, Neus (Hospital Clínic i Provincial de Barcelona) ;
Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Allen, Isabel (University of California San Francisco) ;
Mumford, Paige (University of California, San Francisco) ;
Essanaa, Youssef M. (University of California, San Francisco) ;
Le, Michael M. (University of California, San Francisco) ;
You, Michelle (University of California, San Francisco, California) ;
Grinberg, Lea T. (University of California, San Francisco) ;
Rosen, Howard J. (University of California, San Francisco) ;
Neylan, Thomas C. (San Francisco VA Medical Center) ;
Kramer, Joel H. (University of California, San Francisco) ;
Walsh, Christine M. (University of California, San Francisco, California) ;
Universitat Autònoma de Barcelona
There is an increasing awareness that sleep disturbances are a risk factor for dementia. Prior case-control studies suggested that brain grey matter (GM) changes involving cortical (i. e, prefrontal areas) and subcortical structures (i. [...]
2021 - 10.1371/journal.pone.0252076
PloS one, Vol. 16 (may 2021)
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13 p, 2.1 MB |
Sex differences in the behavioral variant of frontotemporal dementia : A new window to executive and behavioral reserve
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Casaletto, Kaitlin B. (University of California) ;
Borrego-Écija, Sergi (Universitat de Barcelona) ;
Arenaza-Urquijo, Eider (Fundació Pasqual Maragall) ;
Wolf, Amy (University of California) ;
Cobigo, Yann (University of California) ;
Goh, Sheng Yang M. (University of California) ;
Staffaroni, Adam M. (University of California) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Iulita, M. Florencia (Women's Brain Project) ;
Brugulat-Serrat, Anna (Fundació Pasqual Maragall) ;
Llado Plarrumani, Albert (Universitat de Barcelona) ;
Grinberg, Lea T. (University of California) ;
Possin, Katherine (University of California) ;
Rankin, Katherine P. (University of California) ;
Kramer, Joel H. (University of California) ;
Rabinovici, Gil D. (University of California) ;
Boxer, Adam (University of California) ;
Seeley, William W. (University of California) ;
Sturm, Virginia E. (University of California) ;
Gorno-Tempini, Maria Luisa (University of California) ;
Miller, Bruce L. (University of California) ;
Sanchez-Valle, Raquel (Universitat de Barcelona) ;
Perry, David C. (University of California) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Rosen, Howard J. (University of California) ;
Universitat Autònoma de Barcelona
Biological sex is an increasingly recognized factor driving clinical and structural heterogeneity in Alzheimer's disease, but its role in the behavioral variant of frontotemporal dementia (bvFTD) is unknown. [...]
2021 - 10.1002/alz.12299
Alzheimer's & Dementia, Vol. 17 (february 2021) , p. 1329-1341
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17 p, 1023.4 KB |
Selective vulnerability to atrophy in sporadic Creutzfeldt-Jakob disease
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Younes, Kyan (University of California, San Francisco (UCSF)) ;
Rojas, Julio C. (University of California, San Francisco (UCSF)) ;
Wolf, Amy (University of California, San Francisco (UCSF)) ;
Sheng-Yang, Goh M. (University of California, San Francisco (UCSF)) ;
Paoletti, Matteo (IRCCS Mondino Foundation) ;
Toller, Gianina (University of California, San Francisco (UCSF)) ;
Caverzasi, Eduardo (University of California, San Francisco (UCSF)) ;
Mandelli, Maria Luisa (University of California, San Francisco (UCSF)) ;
Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Kramer, Joel H. (University of California, San Francisco (UCSF)) ;
Cobigo, Yann (University of California, San Francisco (UCSF)) ;
Miller, Bruce L. (University of California, San Francisco (UCSF)) ;
Rosen, Howard J. (University of California, San Francisco (UCSF)) ;
Geschwind, Michael D. (University of California, San Francisco (UCSF)) ;
Universitat Autònoma de Barcelona
Identification of brain regions susceptible to quantifiable atrophy in sporadic Creutzfeldt-Jakob disease (sCJD) should allow for improved understanding of disease pathophysiology and development of structural biomarkers that might be useful in future treatment trials. [...]
2021 - 10.1002/acn3.51290
Annals of Clinical and Translational Neurology, Vol. 8 (may 2021) , p. 1183-1199
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14 p, 1.2 MB |
Diagnostic Utility of Measuring Cerebral Atrophy in the Behavioral Variant of Frontotemporal Dementia and Association With Clinical Deterioration
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Falgàs, Neus (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Friedberg, Adit (University of California. Department of Neurology) ;
Castro-Suárez, Sheila (University of California. Department of Neurology) ;
Keret, Ophir (University of California. Department of Neurology) ;
Rogers, Nicole (University of California. Department of Neurology) ;
Oz, Didem (University of California. Department of Neurology) ;
Nigro, Salvatore (Magna Graecia University (Catanzaro, Itàlia). Neuroscience Centre) ;
Quattrone, Andrea (Magna Graecia University (Catanzaro, Itàlia). Institute of Neurology) ;
Quattrone, Aldo (Institute of Molecular Bioimaging and Physiology (Catanzaro, Itàlia)) ;
Wolf, Amy (University of California. Department of Neurology) ;
Younes, Kyan (University of California. Department of Neurology) ;
Santos-Santos, Miguel (Institut d'Investigació Biomèdica Sant Pau) ;
Borrego-Écija, Sergi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cobigo, Yann (University of California. Department of Neurology) ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Llado Plarrumani, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Sanchez-Valle, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Grinberg, Lea T. (University of California. Department of Neurology) ;
Spina, Salvatore (University of California. Department of Neurology) ;
Kramer, Joel H. (University of California. Department of Neurology) ;
Rabinovici, Gil D. (University of California. Department of Neurology) ;
Boxer, Adam (University of California. Department of Neurology) ;
Gorno Tempini, Maria Luisa (University of California. Department of Neurology) ;
Miller, Bruce L. (University of California. Department of Neurology) ;
Seeley, William W. (University of California. Department of Neurology) ;
Rosen, Howard J. (University of California. Department of Neurology) ;
Perry, David C. (University of California. Department of Neurology) ;
Universitat Autònoma de Barcelona
Can widely available measures of atrophy on magnetic resonance imaging increase diagnostic certainty of underlying frontotemporal lobar degeneration (FTLD) and estimate clinical deterioration in the behavioral variant of frontotemporal dementia (bvFTD)? This diagnostic/prognostic study investigated the clinical utility of 5 validated visual atrophy scales (VAS) and the Magnetic Resonance Parkinsonism Index. [...]
2021 - 10.1001/jamanetworkopen.2021.1290
JAMA network open, Vol. 4 (march 2021)
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