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Author Correction : DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death
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Bonassi, Stefano (San Raffaele University) ;
Ceppi, Marcello (San Martino Policlinic Hospital) ;
Møller, Peter (University of Copenhagen) ;
Azqueta, Amaya (Universidad de Navarra) ;
Milić, Mirta (Institute for Medical Research and Occupational Health) ;
Neri, Monica (IRCCS San Raffaele Roma) ;
Brunborg, Gunnar (Norwegian Institute of Public Health) ;
Godschalk, Roger (University of Maastricht. Department of Pharmacology and Toxicology) ;
Koppen, Gudrun (Flemish Institute of Technological Research) ;
Langie, Sabine (University of Maastricht. Department of Pharmacology and Toxicology) ;
Teixeira, João Paulo (Instituto de Saúde Pública, Universidade Do Porto) ;
Bruzzone, Marco (San Martino Policlinic Hospital) ;
Da Silva, Juliana (Lutheran University of Brazil) ;
Benedetti, Danieli (Lutheran University of Brazil) ;
Cavallo, Delia (Department of Occupational and Environmental Medicine, Epidemiology and Hygiene) ;
Ursini, Cinzia Lucia (Department of Occupational and Environmental Medicine, Epidemiology and Hygiene) ;
Giovannelli, Lisa (University of Florence. Department NEUROFARBA) ;
Moretti, Silvia (University of Florence. Department of Health Sciences) ;
Riso, Patrizia (University of Milan. Department of Food, Environmental and Nutritional Sciences) ;
Del Bo', Cristian (University of Milan. Department of Food, Environmental and Nutritional Sciences) ;
Russo, Patrizia (San Raffaele University) ;
Dobrzyńska, Malgorzata (National Institute of Public Health NIH) ;
Goroshinskaya, Irina A. (National Medical Research Center for Oncology) ;
Surikova, Ekaterina I. (National Medical Research Center for Oncology) ;
Staruchova, Marta (Slovak Medical University) ;
Barančoková, Magdalena (Slovak Medical University) ;
Volkovova, Katarina (Slovak Medical University) ;
Kažimirova, Alena (Slovak Medical University) ;
Smolkova, Bozena (Slovak Academy of Sciences) ;
Laffon, Blanca (Instituto de Investigación Biomédica de A Coruña) ;
Valdiglesias, Vanessa (Universidade da Coruña) ;
Pastor Benito, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Gajski, Goran (Institute for Medical Research and Occupational Health) ;
Spremo-Potparević, Biljana (University of Belgrade) ;
Živković, Lada (University of Belgrade) ;
Boutet-Robinet, Elisa (Université de Toulouse) ;
Perdry, Hervé (Univ Paris-Saclay) ;
Lebailly, Pierre (Centre François Baclesse (Caen, França)) ;
Perez, Carlos L. (Universidad de Ciencias Médicas de La Habana) ;
Basaran, Nursen (Hacettepe University. Department of Pharmaceutical Toxicology) ;
Nemeth, Zsuzsanna (National Public Health Center) ;
Safar, Anna (National Public Health Center) ;
Dusinska, Maria (Health Effects Laboratory) ;
Collins, Andrew R (University of Oslo. Department of Nutrition)
2021 -  10.1038/s41598-021-98620-6
Scientific reports, Vol. 11 (September 2021) , art. 19043
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11 p, 1.1 MB |
DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death
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Bonassi, Stefano (San Raffaele University) ;
Ceppi, Marcello (San Martino Policlinic Hospital) ;
Møller, Peter (University of Copenhagen) ;
Azqueta, Amaya (Universidad de Navarra) ;
Milić, Mirta (Institute for Medical Research and Occupational Health) ;
Neri, Monica (IRCCS San Raffaele Roma) ;
Brunborg, Gunnar (Norwegian Institute of Public Health) ;
Godschalk, Roger (University of Maastricht. Department of Pharmacology and Toxicology) ;
Koppen, Gudrun (Flemish Institute of Technological Research) ;
Langie, Sabine (University of Maastricht. Department of Pharmacology and Toxicology) ;
Teixeira, João Paulo (Instituto de Saúde Pública, Universidade Do Porto) ;
Bruzzone, Marco (San Martino Policlinic Hospital) ;
Da Silva, Juliana (Lutheran University of Brazil) ;
Benedetti, Danieli (Lutheran University of Brazil) ;
Cavallo, Delia (Department of Occupational and Environmental Medicine, Epidemiology and Hygiene) ;
Ursini, Cinzia Lucia (Department of Occupational and Environmental Medicine, Epidemiology and Hygiene) ;
Giovannelli, Lisa (University of Florence. Department NEUROFARBA) ;
Moretti, Silvia (University of Florence. Department of Health Sciences) ;
Riso, Patrizia (University of Milan. Department of Food, Environmental and Nutritional Sciences) ;
Del Bo', Cristian (University of Milan. Department of Food, Environmental and Nutritional Sciences) ;
Russo, Patrizia (San Raffaele University) ;
Dobrzyńska, Malgorzata (National Institute of Public Health NIH) ;
Goroshinskaya, Irina A. (National Medical Research Center for Oncology) ;
Surikova, Ekaterina I. (National Medical Research Center for Oncology) ;
Staruchova, Marta (Slovak Medical University) ;
Barančoková, Magdalena (Slovak Medical University) ;
Volkovova, Katarina (Slovak Medical University) ;
Kažimirova, Alena (Slovak Medical University) ;
Smolkova, Bozena (Slovak Academy of Sciences) ;
Laffon, Blanca (Instituto de Investigación Biomédica de A Coruña) ;
Valdiglesias, Vanessa (Universidade da Coruña) ;
Pastor Benito, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Gajski, Goran (Institute for Medical Research and Occupational Health) ;
Spremo-Potparević, Biljana (University of Belgrade) ;
Živković, Lada (University of Belgrade) ;
Boutet-Robinet, Elisa (Université de Toulouse) ;
Perdry, Hervé (Univ Paris-Saclay) ;
Lebailly, Pierre (Centre François Baclesse (Caen, França)) ;
Perez, Carlos L. (Universidad de Ciencias Médicas de La Habana) ;
Basaran, Nursen (Hacettepe University. Department of Pharmaceutical Toxicology) ;
Nemeth, Zsuzsanna (National Public Health Center) ;
Safar, Anna (National Public Health Center) ;
Dusinska, Maria (Health Effects Laboratory) ;
Collins, Andrew R (University of Oslo. Department of Nutrition)
The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, mortality by cause, and cancer incidence associated to DNA damage, a cohort of 2,403 healthy individuals (25,978 person-years) screened in 16 laboratories using the comet assay between 1996 and 2016 was followed-up. [...]
2021 - 10.1038/s41598-021-95976-7
Scientific reports, Vol. 11 (August 2021) , art. 16793
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10 p, 788.5 KB |
Serum osteoprotegerin in prevalent hemodialysis patients : associations with mortality, atherosclerosis and cardiac function
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Collado, S. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Coll, Elisabet (Institut d'Investigació Biomèdica Sant Pau) ;
Nicolau, Carlos (Hospital Clínic i Provincial de Barcelona) ;
Azqueta, Manel (Hospital Clínic i Provincial de Barcelona) ;
Pons, Mercedes (CETIRSA Barcelona) ;
Cruzado, Josep María (Institut Hemodiàlisi Barcelona) ;
de la Torre, Bernat (Diaverum, Barcelona) ;
Deulofeu, Ramón (Hospital Clínic i Provincial de Barcelona) ;
Mojal, Sergi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Pascual, Julio (Pascual Santos) (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cases Amenós, Aleix (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona
To assess whether serum osteoprotegerin (OPG) and/or fetuin-A predict mortality and cardiovascular (CV) morbidity and mortality in hemodialysis patients. Multicenter, observational, prospective study that included 220 hemodialysis patients followed up for up to 6 years. [...]
2017 - 10.1186/s12882-017-0701-8
BMC Nephrology, Vol. 18 (september 2017)
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The hCOMET project : International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders
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Milić, Mirta (Institute for Medical Research and Occupational Health, Croatia) ;
Ceppi, Marcello (San Martino Policlinic Hospital, Italy) ;
Bruzzone, Marco (San Martino Policlinic Hospital, Italy) ;
Azqueta, Amaya (Instituto de Investigación Sanitaria de Navarra) ;
Brunborg, Gunnar (Norwegian Institute of Public Health) ;
Godschalk, Roger (University of Maastricht) ;
Koppen, Gudrun (Flemish Institute of Technological Research, Environmental Risk and Health unit VITO - BIOMo, Belgium) ;
Langie, Sabine (University of Maastricht) ;
Møller, Peter (University of Copenhagen) ;
Teixeira, João Paulo (Universidade do Porto) ;
Alija, Avdulla (University of Prishtina, Kosovo) ;
Anderson, Diana (University of Bradford) ;
Andrade, Vanessa (University of Southern Santa Catarina, Brazil) ;
Andreoli, Cristina (Istituto Superiore di Sanità) ;
Asllani, Fisnik (University of Prishtina, Kosovo) ;
Bangkoglu, Ezgi Eyluel (University of Wuerzburg) ;
Barančoková, Magdalena (Slovak Medical University) ;
Basaran, Nursen (Hacettepe University, Turkey) ;
Boutet-Robinet, Elisa (Université de Toulouse) ;
Buschini, Annamaria (University of Parma) ;
Cavallo, Delia (Italian Workers' Compensation Authority (INAIL)) ;
Pereira, Cristiana Costa (Universidade do Porto) ;
Costa, Carla (Universidade do Porto) ;
Costa, Solange (Universidade do Porto) ;
Da Silva, Juliana (Lutheran University of Brazil (ULBRA)) ;
Del Bo', Cristian (University of Milan) ;
Srećković, Vesna Dimitrijević (University of Belgrade) ;
Djelić, Ninoslav (University of Belgrade) ;
Dobrzyńska, Malgorzata (National Institute of Public Health - National Institute of Hygiene, Poland) ;
Duračková, Zdenka (Comenius University, Slovakia) ;
Dvořáková, Monika (Comenius University, Slovakia) ;
Gajski, Goran (Institute for Medical Research and Occupational Health, Croatia) ;
Galati, Serena (University of Parma) ;
Lima, Omar García (Center for RadiationProtection and Hygiene, Cuba) ;
Giovannelli, Lisa (University of Florence) ;
Goroshinskaya, Irina A. (National Medical Research Center for Oncology, Russia) ;
Grindel, Annemarie (University of Vienna) ;
Gutzkow, Kristine B. (Norwegian Institute of Public Health (NIPH)) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández, Carlos (Instituto de Ciencias Básicas y Preclínicas "Victoria de Giron", Cuba) ;
Holven, Kirsten B. (University of Oslo) ;
Ibero-Baraibar, Idoia (Universidad Pública de Navarra) ;
Ottestad, Inger (University of Oslo) ;
Kadioglu, Ela (Gazi University, Turkey) ;
Kažimirová, Alena (Slovak Medical University) ;
Kuznetsova, Elena (Russian Academy of Sciences) ;
Ladeira, Carina (Universidade NOVA de Lisboa) ;
Lamonaca, Palma (San Raffaele University) ;
Lebailly, Pierre (Centre François Baclesse (Caen, França)) ;
Louro, Henriqueta (ToxOmics, NMS, NOVA University of Lisbon, Lisbon, Portugal) ;
Cardoso, Tania Mandina (Center for RadiationProtection and Hygiene, Cuba) ;
Marcon, Francesca (Istituto Superiore di Sanità) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Moretti, Massimo (University of Perugia) ;
Moretti, Silvia (Palagi Hospital, Italy) ;
Najafzadeh, Mojgan (University of Bradford) ;
Nemeth, Zsuzsanna (National Public Health CenterHungary) ;
Neri, Monica (San Raffaele University) ;
Novotna, Bozena (The Czech Academy of Sciences) ;
Orlow, Irene (Memorial Sloan Kettering Cancer Center, Epidemiology and Biostatistics,USA) ;
Paduchova, Zuzana (Comenius University, Slovakia) ;
Pastor, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Perdry, Hervé (Univ Paris-Saclay) ;
Spremo-Potparević, Biljana (University of Belgrade) ;
Ramadhani, Dwi (National Nuclear Energy Agency of Indonesia) ;
Riso, Patrizia (University of Milan) ;
Rohr, Paula (University of Southern Santa Catarina, Brazil) ;
Rojas, Emilio (Universidad Nacional Autónoma de México) ;
Rossner, Pavel (The Czech Academy of Sciences) ;
Safar, Anna (National Public Health Center, Hungary) ;
Sardas, Semra (Istinye University, Turkey) ;
Silva, Maria João (University of Lisbon) ;
Sirota, Nikolay (Russian Academy of Sciences) ;
Smolkova, Bozena (Slovak Academy of Sciences) ;
Staruchova, Marta (Slovak Medical University) ;
Stetina, Rudolf (University of Defence, Czech Republic) ;
Stopper, Helga (University of Wuerzburg,Germany) ;
Surikova, Ekaterina I. (National Medical Research Center for Oncology, Russia) ;
Ulven, Stine M. (University of Oslo) ;
Ursini, Cinzia Lucia (Italian Workers' Compensation Authority (INAIL)) ;
Valdiglesias, Vanessa (Universidade da Coruña) ;
Valverde, Mahara (Universidad Nacional Autónoma de México) ;
Vodicka, Pavel (Experimental Medicine, Molecular Biology of Cancer, IEM AVCR, Czech Republic) ;
Volkovova, Katarina (Slovak Medical University) ;
Wagner, Karl-Heinz (University of Vienna) ;
Živković, Lada (University of Belgrade) ;
Dušinská, Maria (NILU, Health Effects Laboratory, Norway) ;
Collins, Andrew R. (University of Oslo) ;
Bonassi, Stefano (San Raffaele University)
The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification of those factors that can explain the large inter-individual and inter-laboratory variation. [...]
2021 - 10.1016/j.mrrev.2021.108371
Mutation research. Reviews in mutation research, Vol. 787 (February 2021) , art. 108371
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Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes
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Sevilla, Julián (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Navarro Ordóñez, Susanna (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Río, Paula (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Sánchez-Domínguez, Rebeca (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Zubicaray, Josune (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Gálvez, Eva (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Merino, Eva (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Sebastián, Elena (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Azqueta, Carmen (Banc de Sang i Teixits de Catalunya) ;
Casado, José A. (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Segovia, José C. (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Alberquilla, Omaira (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Bogliolo, Massimo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Román-Rodríguez, Francisco J. (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Giménez, Yari (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Larcher, Lise (Université de Paris. Institut de Recherche Saint-Louis) ;
Salgado Sánchez, Rocío Nieves (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Pujol, Roser M. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hladun, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castillo, Ana (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Soulier, Jean (Université de Paris. Institut de Recherche Saint-Louis) ;
Querol, Sergi (Banc de Sang i Teixits de Catalunya) ;
Fernández, Jesús (Banc de Sang i Teixits de Catalunya) ;
Schwartz, Jonathan (Rocket Pharmaceuticals Inc. (New York)) ;
García de Andoín, Nagore (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
López, Ricardo (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Català, Albert (Institut de Recerca Pediàtrica Sant Joan de Déu) ;
Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Díaz de Heredia, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bueren, Juan (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz)
Difficulties in the collection of hematopoietic stem and progenitor cells (HSPCs) from Fanconi anemia (FA) patients have limited the gene therapy in this disease. We have investigated (, NCT02931071) the safety and efficacy of filgrastim and plerixafor for mobilization of HSPCs and collection by leukapheresis in FA patients. [...]
2021 - 10.1016/j.omtm.2021.06.001
Molecular Therapy. Methods & Clinical Development, Vol. 22 (September 2021) , p. 66-75
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