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10 p, 481.8 KB |
Towards new recommendations to reduce the burden of alcohol-induced hypertension in the European Union
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Rehm, Jürgen (Technische Universität Dresden) ;
Anderson, Peter (Maastricht University) ;
Prieto, Jose Angel (Primary Care Spanish Society SEMERGEN) ;
Armstrong, Iain (Health and Wellbeing Directorate. Public Health England) ;
Aubin, Henri-Jean (University Paris-Sud) ;
Bachmann, Michael (Copentown Healthcare Consultants) ;
Bastida Bastus, Nuria (Raval Nord) ;
Brotons, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Burton, Robyn (Public Health England) ;
Cardoso, Mabnuel (General Directorate for Intervention on Addictive Behaviours and Dependencies (SICAD)) ;
Colom, Joan (Generalitat de Catalunya) ;
Duprez, Daniel (University of Minnesota) ;
Gmel, Gerrit (University of New South Wales) ;
Gual, Antoni (Hospital Clínic i Provincial de Barcelona) ;
Kraus, Ludwig (Stockholm University) ;
Kreutz, Reinhold (Charité - Universitätsmedizin Berlin) ;
Liira, Helena (University of Helsinki) ;
Manthey, Jakob (Technische Universität Dresden) ;
Møller, Lars (WHO Regional Office for Europe) ;
Okruhlica, Lubomír (Centrum pre Liecbu Drogovych Zavislosti) ;
Roerecke, Michael (University of Toronto) ;
Scafato, Emanuele (Società Italiana di Alcologia (SIA)) ;
Schulte, Bernd (Hamburg University) ;
Segura-Garcia, Lidia (Generalitat de Catalunya) ;
Shield, Kevin David (Institute for Mental Health Policy Research) ;
Sierra, Cristina (Hospital Clínic i Provincial de Barcelona) ;
Vyshinskiy, Konstantin (Federal Medical Research Centre for Psychiatry and Narcology n.a. V. Serbsky) ;
Wojnar, Marcin (Medical University of Warsaw) ;
Zarco, José (Ibiza Primary Health Care Center) ;
Universitat Autònoma de Barcelona
Hazardous and harmful alcohol use and high blood pressure are central risk factors related to premature non-communicable disease (NCD) mortality worldwide. A reduction in the prevalence of both risk factors has been suggested as a route to reach the global NCD targets. [...]
2017 -  10.1186/s12916-017-0934-1
BMC Medicine, Vol. 15 Núm. 1 (28 2017) , p. 173
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15 p, 2.2 MB |
Recovering What Matters : High Protein Recovery after Endotoxin Removal from LPS-Contaminated Formulations Using Novel Anti-Lipid A Antibody Microparticle Conjugates
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Casonato Melo, Cristiane (Paris Lodron University of Salzburg. Department of Biosciences & Medical Biology) ;
Fux, Alexandra C. (Paris Lodron University of Salzburg. Department of Biosciences & Medical Biology) ;
Himly, Martin (Paris Lodron University of Salzburg. Department of Biosciences & Medical Biology) ;
Bastús, Neus G (Institut Català de Nanociència i Nanotecnologia) ;
Schlahsa, Laura (Miltenyi Biotec B.V. & Co) ;
Siewert, Christiane (Miltenyi Biotec B.V. & Co) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Duschl, Albert (Paris Lodron University of Salzburg. Department of Biosciences & Medical Biology) ;
Gessner, Isabel (Miltenyi Biotec B.V. & Co) ;
Fauerbach, Jonathan A. (Miltenyi Biotec B.V. & Co)
Endotoxins or lipopolysaccharides (LPS), found in the outer membrane of Gram-negative bacterial cell walls, can stimulate the human innate immune system, leading to life-threatening symptoms. Therefore, regulatory limits for endotoxin content apply to injectable pharmaceuticals, and excess LPS must be removed before commercialization. [...]
2023 - 10.3390/ijms241813971
International journal of molecular sciences, Vol. 24, Issue 18 (September 2023) , art. 13971
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10 p, 8.1 MB |
Facet-engineered TiO2 drives photocatalytic activity and stability of supported noble metal clusters during H2 evolution
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Chen, Yufen (Universitat Politècnica de Catalunya. Departament d'Enginyeria Química) ;
Soler, Lluís (Universitat Politècnica de Catalunya. Departament d'Enginyeria Química) ;
Cazorla, Claudio (Universitat Politècnica de Catalunya. Departament de Física) ;
Oliveras i Solà, Jana (Institut Català de Nanociència i Nanotecnologia) ;
Bastús, Neus G (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Llorca, Jordi (Universitat Politècnica de Catalunya. Departament d'Enginyeria Química)
Metal clusters supported on TiO are widely used in many photocatalytic applications, including pollution control and production of solar fuels. Besides high photoactivity, stability during the photoreaction is another essential quality of high-performance photocatalysts, however systematic studies on this attribute are absent for metal clusters supported on TiO. [...]
2023 - 10.1038/s41467-023-41976-2
Nature communications, Vol. 14 (October 2023) , art. 6165
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13 p, 10.6 MB |
Exploiting endocytosis for transfection of mRNA for cytoplasmatic delivery using cationic gold nanoparticles
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Gustà, Muriel F. (Institut Català de Nanociència i Nanotecnologia) ;
Edel, Michael J (Universitat Autònoma de Barcelona) ;
Salazar Montoya, Vivian Angélica (Institut Català de Nanociència i Nanotecnologia) ;
Alvarez-Palomo, Belén (Banc de Sang i Teixits) ;
Juan, Manel (Hospital Clínic i Provincial de Barcelona) ;
Broggini, Massimo (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ;
Damia, Giovanna (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ;
Bigini, Paolo (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ;
Corbelli, Alessandro (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ;
Fiordaliso, Fabio (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ;
Barbul, Alexander (Tel Aviv University) ;
Korenstein, Rafi (Tel Aviv University) ;
Bastús, Neus G (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Gene therapy holds promise to cure various diseases at the fundamental level. For that, efficient carriers are needed for successful gene delivery. Synthetic 'non-viral' vectors, as cationic polymers, are quickly gaining popularity as efficient vectors for transmitting genes. [...]
2023 - 10.3389/fimmu.2023.1128582
Frontiers in immunology, Vol. 14 (May 2023) , art. 1128582
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13 p, 1.9 MB |
Nanoceria as Safe Contrast Agents for X-ray CT Imaging
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García, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cámara, Juan Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Boullosa, Ana María (Networking Research Centre on Bioengineering) ;
Gustà, Muriel F. (Institut Català de Nanociència i Nanotecnologia) ;
Mondragón, Laura (Institut Català de Nanociència i Nanotecnologia) ;
Schwartz, Simon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Casals, Eudald (Wuyi University) ;
Abasolo, Ibane (Hospital Universitari Vall d'Hebron) ;
Bastús, Neus G (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Cerium oxide nanoparticles (CeONPs) have exceptional catalytic properties, rendering them highly effective in removing excessive reactive oxygen species (ROS) from biological environments, which is crucial in safeguarding these environments against radiation-induced damage. [...]
2023 - 10.3390/nano13152208
Nanomaterials, Vol. 13, Issue 15 (August 2023) , art. 2208
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12 p, 2.5 MB |
Asymmetrical Plasmon Distribution in Hybrid AuAg Hollow/Solid Coded Nanotubes
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Genç, Aziz (Institut Català de Nanociència i Nanotecnologia) ;
Patarroyo, Javier (Institut Català de Nanociència i Nanotecnologia) ;
Sancho-Parramon, Jordi (Rudjer Boskovic Institute) ;
Arenal, Raúl (ARAID Foundation) ;
Bastús, Neus G (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arbiol i Cobos, Jordi (Institut Català de Nanociència i Nanotecnologia)
Morphological control at the nanoscale paves the way to fabricate nanostructures with desired plasmonic properties. In this study, we discuss the nanoengineering of plasmon resonances in 1D hollow nanostructures of two different AuAg nanotubes, including completely hollow nanotubes and hybrid nanotubes with solid Ag and hollow AuAg segments. [...]
2023 - 10.3390/nano13060992
Nanomaterials, Vol. 13, Issue 6 (March 2023) , art. 992
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19 p, 9.0 MB |
Variations in Biodistribution and Acute Response of Differently Shaped Titania Nanoparticles in Healthy Rodents
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Violatto, Martina B. (Istituto di Ricerche Farmacologiche Mario Negri IRCCS) ;
Sitia, Giovanni (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Talamini, Laura (Istituto di Ricerche Farmacologiche Mario Negri IRCCS) ;
Morelli, Annalisa (Istituto di Ricerche Farmacologiche Mario Negri IRCCS) ;
Tran, Ngoc Lan (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Zhang, Qian (Shanghai Jiao Tong University) ;
Masood, Atif (Karachi Institute of Radiotherapy and Nuclear Medicine) ;
Pelaz, Beatriz (Universidade de Santiago de Compostela. Departamento de Química Inorgánica) ;
Chakraborty, Indranath (Indian Institute of Technology Kharagpur) ;
Cui, Daxiang (Shanghai Jiao Tong University) ;
Parak, Wolfgang J. (Universität Hamburg) ;
Salmona, Mario (Istituto di Ricerche Farmacologiche Mario Negri IRCCS) ;
Bastús, Neus G (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Bigini, Paolo (Istituto di Ricerche Farmacologiche Mario Negri IRCCS)
Titanium dioxide nanoparticles (TiO NPs) are one of the main sources of the nanoparticulate matter exposure to humans. Although several studies have demonstrated their potential toxic effects, the real nature of the correlation between NP properties and their interaction with biological targets is still far from being fully elucidated. [...]
2023 - 10.3390/nano13071174
Nanomaterials, Vol. 13, Issue 7 (April 2023) , art. 1174
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20 p, 4.6 MB |
Exploring the Long-Term Tissue Accumulation and Excretion of 3 nm Cerium Oxide Nanoparticles after Single Dose Administration
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Ernst, Lena M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mondragón, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ramis, Joana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gustà, Muriel F. (Institut Català de Nanociència i Nanotecnologia) ;
Yudina, Tetyana (Institut Català de Nanociència i Nanotecnologia) ;
Casals, Eudald (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Fernández-Varo, Guillermo (Hospital Clínic i Provincial de Barcelona) ;
Casals, Gregori (Hospital Clínic i Provincial de Barcelona) ;
Jiménez, Wladimiro (Hospital Clínic i Provincial de Barcelona) ;
Puntes, Víctor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Nanoparticle (NP) pharmacokinetics significantly differ from traditional small molecule principles. From this emerges the need to create new tools and concepts to harness their full potential and avoid unnecessary risks. [...]
2023 - 10.3390/antiox12030765
Antioxidants, Vol. 12, Issue 3 (March 2023) , art. 765
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