Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality
Miñambres, Inka (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Sardà, Helena (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Urgell, Eulalia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Genua, Idoia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Ramos, Analía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Fernández-Ananin, Sonia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Balaguè Ponz, Carmen (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Sanchez-Quesada, Jose Luis (Institut d'Investigació Biomèdica Sant Pau)
Bassas, Lluís (Fundació Puigvert)
Pérez Pérez, Antonio (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Universitat Autònoma de Barcelona

Date:	2022
Abstract:	Obesity is associated with hypogonadism, sexual dysfunction, and impaired fertility in men. However, its effects on semen parameters or sexual function remain debatable. This paper involves a longitudinal study in men submitted for obesity surgery at a university tertiary hospital. Patients were studied at baseline and at 6, 12, and 18 months after obesity surgery. At each visit, anthropometry measures were collected and hormonal and semen parameters were studied. Sexual function was evaluated with the International Index of Erectile Function (IIEF). A total of 12 patients were included. The average body mass index of patients decreased from 42. 37 ± 4. 44 to 29. 6 ± 3. 77 kg/m 2 at 18 months after surgery (p < 0. 05). Hormonal parameters improved after obesity surgery. The proportion of sperm cells with normal morphology tended to decrease from baseline and became most significant at 18 months (5. 83 ± 4. 50 vs. 2. 82 ± 2. 08). No significant changes were found in the remaining semen parameters. Erectile function improved significantly at six months after surgery. The authors believe that, in general, the effects of obesity surgery on fertility may be limited or even deleterious (at least in the short and midterm follow-up).
Grants:	Instituto de Salud Carlos III PI20-00334
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Fertility ; Hypogonadism ; Obesity ; Obesity surgery ; Sperm
Published in:	Journal of clinical medicine, Vol. 11 (august 2022) , ISSN 2077-0383

DOI: 10.3390/jcm11175126
PMID: 36079056

9 p, 962.9 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles