Poorer quality of life and treatment satisfaction is associated with diabetic retinopathy in patients with type 1 diabetes without other advanced late complications
Granado-Casas, Minerva (Institut d'Investigació Biomèdica Sant Pau)
Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau)
Ramírez-Morros, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Martín, Mariona (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Alcubierre, Nuria (Universitat de Lleida)
Martínez-Alonso, M. (Institut de Recerca Biomèdica de Lleida)
Valldeperas, Xavier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Traveset, A. (Hospital Universitari Arnau de Vilanova)
Rubinat, Esther (Universitat de Lleida)
Lucas-Martin, Ana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Hernández, Marta (Hospital Universitari Arnau de Vilanova)
Alonso Pedrol, Núria (Instituto de Salud Carlos III)
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau)
Universitat Autònoma de Barcelona

Date:	2019
Abstract:	Diabetic retinopathy (DR) may potentially cause vision loss and affect the patient's quality of life (QoL) and treatment satisfaction (TS). Using specific tools, we aimed to assess the impact of DR and clinical factors on the QoL and TS in patients with type 1 diabetes. This was a cross-sectional, two-centre study. A sample of 102 patients with DR and 140 non-DR patients were compared. The Audit of Diabetes-Dependent Quality of Life (ADDQoL-19) and Diabetes Treatment Satisfaction Questionnaire (DTSQ-s) were administered. Data analysis included bivariate and multivariable analysis. Patients with DR showed a poorer perception of present QoL (p = 0. 039), work life (p = 0. 037), dependence (p = 0. 010), and had a lower average weighted impact (AWI) score (p = 0. 045). Themultivariable analysis showed that DR was associated with a lower present QoL (p = 0. 040), work life (p = 0. 036) and dependence (p = 0. 016). With regards to TS, DR was associated with a higher perceived frequency of hypoglycaemia (p = 0. 019). In patients with type 1 diabetes, the presence of DR is associated with a poorer perception of their QoL. With regard to TS, these subjects also show a higher perceived frequency of hypoglycaemia.
Grants:	Ministerio de Economía y Competitividad PI12/00183 Ministerio de Economía y Competitividad PI15/00625 Ministerio de Educación, Cultura y Deporte FPU15/03005
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Diabetic retinopathy ; Patient-reported outcomes ; Quality of life ; Treatment satisfaction ; Type 1 diabetes
Published in:	Journal of clinical medicine, Vol. 8 Núm. 3 (march 2019) , p. 377, ISSN 2077-0383

DOI: 10.3390/jcm8030377
PMID: 30889868

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The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles