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7 p, 518.4 KB |
Langerhans cell histiocytosis. Advances in pathogenesis and clinical practice Histiocitosis de células de Langerhans. Avances en la patogenia y práctica clínica
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Astigarraga, Itziar (Universidad del País Vasco) ;
García-Obregón, Susana (Universidad del País Vasco) ;
Pérez-Martínez, Antonio (Instituto de Investigación del Hospital La Paz) ;
Gutiérrez-Carrasco, Ignacio (Hospital Infantil Virgen del Rocío) ;
Santa-María, Vicente (Hospital Sant Joan de Deu) ;
Rodríguez-Vigil Iturrate, Carmen (Hospital Universitario Miguel Servet (Saragossa)) ;
Lorite Reggiori, Mikael (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Murciano Carrillo, Thais (Hospital Universitari Vall d'Hebron) ;
Torrent, Montse (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Langerhans cell histiocytosis (LCH) is a type of myeloid neoplasia that can affect different organs or tissues and exhibits substantial variability in its clinical presentation and biological behaviour, so it may mimic different diseases. [...]
2022 -  10.1016/j.anpedi.2022.05.002
Anales de pediatría, Vol. 97 Núm. 2 (agosto 2022) , p. 130.e1-130.e7
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11 p, 1.4 MB |
Revisiting the usefulness of the short acute octreotide test to predict treatment outcomes in acromegaly
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Marques-Pamies, Montserrat (Hospital Municipal de Badalona) ;
Gil, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Valassi, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández García, Marta (Hospital Universitari Arnau de Vilanova) ;
Biagetti, Betina (Hospital Universitari Vall d'Hebron) ;
Giménez-Palop, Olga (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Martínez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Carrato, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pons, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Villar-Taibo, Rocío (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Araujo-Castro, Marta (Hospital Ramón y Cajal) ;
Blanco, Concepción (Hospital Universitario Príncipe de Asturias) ;
Simón, Inmaculada (Hospital Universitari Joan XXIII de Tarragona) ;
Simó-Servat, Andreu (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Xifra, Gemma (Hospital Universitari de Girona Doctor Josep Trueta) ;
Vázquez, Federico (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pavón, Isabel (Hospital Universitario de Getafe) ;
García-Centeno, Rogelio (Hospital General Universitari Gregorio Marañón) ;
Zavala, Roxana (Hospital Universitari Joan XXIII de Tarragona) ;
Hanzu, Felicia A (Hospital Clínic i Provincial de Barcelona) ;
Mora, Mireia (Hospital Clínic i Provincial de Barcelona) ;
Aulinas, Anna (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vilarrasa, Nuria (Instituto de Salud Carlos III) ;
Librizzi, Soledad (Hospital Universitario 12 de Octubre) ;
Calatayud, María (Hospital Universitario 12 de Octubre) ;
de Miguel, Paz (Hospital Clínico San Carlos (Madrid)) ;
Alvarez-Escola, Cristina (Hospital Universitario La Paz) ;
Picó Alfonso, Antonio M (Instituto de Investigación Sanitaria y Biomédica de Alicante) ;
Sampedro, Miguel (Hospital Universitario de La Princesa) ;
Salinas, Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fajardo-Montañana, Carmen (Hospital Universitari de la Ribera) ;
Cámara, Rosa (Hospital Universitari i Politècnic La Fe (València)) ;
Bernabeu Morón, Ignacio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Jordà, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Webb, S. M 1952- (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Marazuela, Mónica (Hospital Universitario de la Princesa (Madrid)) ;
Puig Domingo, Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
We previously described that a short version of the acute octreotide test (sAOT) can predict the response to first-generation somatostatin receptor ligands (SRLs) in patients with acromegaly. We have prospectively reassessed the sAOT in patients from the ACROFAST study using current ultra-sensitive GH assays. [...]
2023 - 10.3389/fendo.2023.1269787
Frontiers in Endocrinology, Vol. 14 (october 2023)
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9 p, 686.2 KB |
The relapsed acute lymphoblastic leukemia network (ReALLNet) : a multidisciplinary project from the spanish society of pediatric hematology and oncology (SEHOP)
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Velasco, Pablo (Hospital Universitari Vall d'Hebron) ;
Bautista, Francisco (Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands) ;
Rubio, Alba (Hospital Infantil Universitario Niño Jesús) ;
Aguilar, Yurena (Hospital Miguel Servet Hospital) ;
Rives, Susana (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Dapena, Jose L (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Pérez, Antonio (Universidad Autónoma de Madrid) ;
Ramirez, Manuel (Fundación Para La Investigación Biomédica Hospital Infantil Universitario Niño Jesús) ;
Saiz-Ladera, Cristina (Fundación Para La Investigación Biomédica Hospital Infantil Universitario Niño Jesús) ;
Izquierdo, Elisa (Hospital Universitario La Paz (Madrid)) ;
Escudero, Adela (Hospital Universitario La Paz (Madrid)) ;
Camós, Mireia (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Vega-García, Nerea (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Ortega, Margarita (Vall d'Hebron Institut d'Oncologia) ;
Hidalgo-Gómez, Gloria (Vall d'Hebron Institut d'Oncologia) ;
Palacio, Carlos (Vall d'Hebron Institut d'Oncologia) ;
Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Montero, Joan (Universitat de Barcelona) ;
Romecín, Paola A. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Zazo, Santiago (Universidad Politécnica de Madrid) ;
Alvarez, Federico (Universidad Politécnica de Madrid) ;
Parras, Juan (Universidad Politécnica de Madrid) ;
Ortega-Sabater, Carmen (University of Castilla-La Mancha) ;
Chulián, Salvador (Universidad de Cádiz) ;
Rosa, María (Universidad de Cádiz) ;
Cirillo, Davide (Barcelona Supercomputing Center) ;
García, Elena (Fundación Para La Investigación Biomédica Hospital Infantil Universitario Niño Jesús) ;
García, Jorge (Fundación Para La Investigación Biomédica Hospital Infantil Universitario Niño Jesús) ;
Manzano-Muñoz, Albert (Universitat de Barcelona) ;
Minguela, Alfredo (Instituto Murciano de Investigación Biosanitaria) ;
Fuster, Jose L. (Instituto Murciano de Investigación Biosanitaria)
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with survival rates exceeding 85%. However, 15% of patients will relapse; consequently, their survival rates decrease to below 50%. [...]
2023 - 10.3389/fped.2023.1269560
Frontiers in Pediatrics, Vol. 11 (september 2023)
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10 p, 701.1 KB |
Circulating non-coding RNAs in biomarker-guided cardiovascular therapy : A novel tool for personalized medicine?
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Gonzalo Calvo, David de (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vea, Ángela (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Bär, C. (Hannover Medical School) ;
Fiedler, J. (Hannover Medical School) ;
Couch, L.S. (Imperial College London) ;
Brotons, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Llorente-Cortes, Vicenta (Institut d'Investigació Biomèdica Sant Pau) ;
Thum, T. (Hannover Medical School) ;
Universitat Autònoma de Barcelona
Current clinical guidelines emphasize the unmet need for technological innovations to guide physician decision-making and to transit from conventional care to personalized cardiovascular medicine. Biomarker-guided cardiovascular therapy represents an interesting approach to inform tailored treatment selection and monitor ongoing efficacy. [...]
2019 - 10.1093/eurheartj/ehy234
European heart journal, Vol. 40 Núm. 20 (january 2019) , p. 1643-1650
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24 p, 1.1 MB |
Highlights from the 2019 International Aspirin Foundation Scientific Conference, Rome, 28 June 2019 : Benefits and risks of antithrombotic therapy for cardiovascular disease prevention
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Walker, Jaqui (International Aspirin Foundation) ;
Cattaneo, Marco (Università degli studi di Milano) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Agnelli, Giancarlo (University of Perugia) ;
Chan, Andrew T. (Harvard Medical School) ;
Lanas, Angel (Universidad de Zaragoza) ;
Rocca, Bianca (Catholic University School of Medicine) ;
Rothwell, Peter (Centre for the Prevention of Stroke and Dementia) ;
Patrignani, Paola ('G.d'Annunizio' University) ;
Langley, Ruth (MRC Clinical Trials Unit at UCL) ;
Vilahur, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Cosentino, Francesco (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Universitat Autònoma de Barcelona
At the 2019 International Aspirin Foundation Scientific Conference 'Benefits and Risks of Antithrombotic Therapy for Cardiovascular Disease Prevention', held in Rome, Italy, international experts sought to discuss and debate the optimal antithrombotic strategy for the secondary prevention of cardiovascular disease (CVD) and to seek agreement around dosing and target populations for aspirin use in primary disease prevention. [...]
2020 - 10.3332/ECANCER.2019.998
ecancermedicalscience, Vol. 14 (13 2020) , p. 998
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13 p, 4.1 MB |
High-precision targeting and destruction of cancer-associated PDGFR-β+ stromal fibroblasts through self-assembling, protein-only nanoparticles
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Voltà-Durán, Eric (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Alba-Castellón, Lorena (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Serna, Naroa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Casanova Rigat, Isolda (Institut d'Investigació Biomèdica Sant Pau) ;
López-Laguna, Hèctor (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Gallardo, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Sánchez Chardi, Alejandro (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Unzueta Elorza, Ugutz (Institut d'Investigació Biomèdica Sant Pau) ;
Vázquez Gómez, Esther (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Mangues, Ramon 1957- (Institut d'Investigació Biomèdica Sant Pau)
The need for more effective and precision medicines for cancer has pushed the exploration of new materials appropriate for drug delivery and imaging, and alternative receptors for targeting. Among the most promising strategies, finding suitable cell surface receptors and targeting agents for cancer-associated platelet derived growth factor receptor β (PDGFR-β)+ stromal fibroblasts is highly appealing. [...]
2023 - 10.1016/j.actbio.2023.09.001
Acta biomaterialia, Vol. 170 (October 2023) , p. 543-555
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12 p, 1.3 MB |
On the clinical relevance of using complete high-resolution HLA typing for an accurate interpretation of posttransplant immune-mediated graft outcomes
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Meneghini, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Perona, Anna (Universitat de Barcelona) ;
Crespo, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bemelman, Frederike (Amsterdam UMC. University Medical Center) ;
Reinke, Petra (Berlin Center for Advanced Therapies) ;
Viklicky, Ondrej (Institute for Clinical and Experimental Medicine) ;
Giral, Magali (Nantes Université) ;
Palou, Eduard (Hospital Clínic i Provincial de Barcelona) ;
Torija, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Donadeu, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Melilli, Edoardo (Hospital Universitari de Bellvitge) ;
Zuñiga, Jose (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sefrin, Anett (Berlin Center for Advanced Therapies) ;
Lachmann, Nils (Charité - Universitätsmedizin Berlin) ;
Hu, Liu (Amsterdam UMC. University Medical Center) ;
Hruba, Petra (Institute for Clinical and Experimental Medicine) ;
Guillot-Gueguen, Cécile (Nantes Université) ;
Brouard, Sophie (Nantes Université) ;
Grinyo, Josep (Universitat de Barcelona) ;
Bestard, Oriol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Complete and high-resolution (HR) HLA typing improves the accurate assessment of donor-recipient compatibility and pre-transplant donor-specific antibodies (DSA). However, the value of this information to identify de novo immune-mediated graft events and its impact on outcomes has not been assessed. [...]
2022 - 10.3389/fimmu.2022.924825
Frontiers in immunology, Vol. 13 (september 2022)
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10 p, 1.1 MB |
Respiratory Polygraphy Patterns and Risk of Recurrent Cardiovascular Events in Patients With Acute Coronary Syndrome
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Zapater, Andrea (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Solelhac, Geoffroy (Lausanne University Hospital) ;
Sánchez-de-la-Torre, Alicia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Gracia-Lavedan, Esther (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Benitez, Ivan David (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Torres, Gerard (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
De Batlle, Jordi (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Haba-Rubio, José (Lausanne University Hospital) ;
Berger, Mathieu (Lausanne University Hospital) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Duran-Cantolla, Joaquín (Arabako Unibertsitate Ospitalea (Vitoria, País Basc)) ;
Urrutia, Amaia (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mediano, Olga (Hospital Universitario de Guadalajara) ;
Masdeu, María José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ordax-Carbajo, Estrella (Hospital Universitario de Burgos) ;
Masa, Juan Fernando (Hospital San Pedro de Alcántara) ;
De la Peña, Mónica (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Mayos, Mercè (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Coloma, Ramon (Complejo Hospitalario Universitario de Albacete) ;
Montserrat, Josep María (Hospital Clínic i Provincial de Barcelona) ;
Chiner, Eusebi (Hospital Universitari Sant Joan d'Alacant) ;
Mínguez, Olga (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Pascual, Lydia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Cortijo, Anunciación (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Martínez López, Dolores (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Dalmases, Mireia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Lee, Chi-Hang (National University of Singapore) ;
McEvoy, R. Doug (Flinders University) ;
Barbé, Ferran (University of Lausanne) ;
Heinzer, Raphael (University of Lausanne) ;
Sánchez-de-la-Torre, Manuel (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Universitat Autònoma de Barcelona
Obstructive sleep apnea (OSA) severity is based on the apnea-hypopnea index (AHI). The AHI is a simplistic measure that is inadequate for capturing disease severity and its consequences in cardiovascular diseases (CVDs). [...]
2022 - 10.3389/fmed.2022.870906
Frontiers in Medicine, Vol. 9 (june 2022)
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