Efficiency of a mechanical device in controlling tracheal cuff pressure in intubated critically ill patients : a randomized controlled study
Nseir, Saad 
(Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Rodriguez, Andrey (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Saludes, Paula (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
De Jonckheere, Julien (University Hospital of Lille (França))
Valles, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Artigas, Antonio 
(Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Martin-Loeches, Ignacio
(St James's University Hospital)
Data: |
2015 |
Resum: |
Cuff pressure (P ) control is mandatory to avoid leakage of oral secretions passing the tracheal tube and tracheal ischemia. The aim of the present trial was to determine the efficacy of a mechanical device (PressureEasy®) in the continuous control of P in patients intubated with polyvinyl chloride (PVC)-cuffed tracheal tubes, compared with routine care using a manometer. This is a prospective, randomized, controlled, cross-over study. All patients requiring intubation with a predicted duration of mechanical ventilation ≥48 h were eligible. Eighteen patients randomly received continuous control of P with PressureEasy® device for 24 h, followed by discontinuous control (every 4 h) with a manual manometer for 24 h, or vice versa. P and airway pressure were continuously recorded. P target was 25 cmHO during the two periods. The percentage of time spent with P 20-30 cmHO (median (IQR) 34 % (17-57) versus 50 % (35-64), p = 0. 184) and the percentage of time spent with P <20 cmHO (23 % (5-63) versus 43 % (16-60), p = 0. 5) were similar during continuous control of P and routine care, respectively. However, the percentage of time spent with P >30 cmHO was significantly higher during continuous control compared with routine care of tracheal cuff (26 % (14-39) versus 7 % (1-18), p = 0. 002). No significant difference was found in P (25 (18-28) versus 21 (18-26), p = 0. 17), mean airway pressure (14 (10-17) versus 14 (11-16), p = 0. 679), or coefficient of variation of P (19 % (11-26) versus 20 % (11-25), p = 0. 679) during continuous control compared with routine care of tracheal cuff, respectively. PressureEasy® did not demonstrate a better control of P between 20 and 30 cmHO, compared with routine care using a manometer. Moreover, the device use resulted in significantly higher time spent with overinflation of tracheal cuff, which might increase the risk for tracheal ischemic lesions. |
Drets: |
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.  |
Llengua: |
Anglès |
Document: |
Article ; recerca ; Versió publicada |
Matèria: |
Cuff pressure ;
Control ;
Tracheal ischemia ;
Microaspiration ;
Mechanical ventilation |
Publicat a: |
Annals of Intensive Care, Vol. 5 (june 2015) , ISSN 2110-5820 |
DOI: 10.1186/s13613-015-0054-z
PMID: 26059205
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Registre creat el 2018-01-31, darrera modificació el 2022-05-23