Contrasting Genomic Diversity in Two Closely Related Postharvest Pathogens : Penicillium digitatum and Penicillium expansum
Julca, Irene (Centre de Regulació Genòmica)
Droby, Samir (Department of Postharvest Science. ARO. The Volcani Center. Israel)
Sela, Noa (Department of Plant Pathology and Weed Research. The Volcani Center. Israel)
Marcet-Houben, Marina (Universitat Pompeu Fabra)
Gabaldón, Toni (Institució Catalana de Recerca i Estudis Avançats)
Universitat Autònoma de Barcelona

Data:	2016
Resum:	Penicillium digitatum and Penicillium expansum are two closely related fungal plant pathogens causing green and blue mold in harvested fruit, respectively. The two species differ in their host specificity, being P. digitatum restricted to citrus fruits and P. expansum able to infect a wide range of fruits after harvest. Although host-specific Penicillium species have been found to have a smaller gene content, it is so far unclear whether these different host specificities impact genome variation at the intraspecific level. Here we assessed genome variation across four P. digitatum and seven P. expansum isolates from geographically distant regions. Our results show very high similarity (average 0. 06 SNPs [single nucleotide polymorphism] per kb) between globally distributed isolates of P. digitatum pointing to a recent expansion of a single lineage. This low level of genetic variation found in our samples contrasts with the higher genetic variability observed in the similarly distributed P. expansum isolates (2. 44 SNPs per kb). Patterns of polymorphism in P. expansum indicate that recombination exists between genetically diverged strains. Consistent with the existence of sexual recombination and heterothallism, which was unknown for this species, we identified the two alternative mating types in different P. expansum isolates. Patterns of polymorphism in P. digitatum indicate a recent clonal population expansion of a single lineage that has reached worldwide distribution. We suggest that the contrasting patterns of genomic variation between the two species reflect underlying differences in population dynamics related with host specificities and related agricultural practices. It should be noted, however, that this results should be confirmed with a larger sampling of strains, as new strains may broaden the diversity so far found in P. digitatum.
Ajuts:	Ministerio de Economía y Competitividad SEV-2012-0208 Ministerio de Economía y Competitividad BIO2012-37161 European Commission 310325 European Commission 642095
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Penicillium ; Genomics ; Genome variation
Publicat a:	Genome biology and evolution, Vol. 8, Núm 1 (January 2016) , p. 218-227, ISSN 1759-6653

DOI: 10.1093/gbe/evv252
PMID: 26672008

Published Version 10 p, 479.1 KB

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