Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
Sanz-Santos, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Serra Mitjà, Pere (Universitat Autònoma de Barcelona. Departament de Medicina)
Andreo García, Felipe (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Torky, Mohamed (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Centeno, Carmen (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Carcereny, Enric (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Fernández Araujo, Esther (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
García-Reina, Samuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Ruiz Manzano, J.. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)

Data:	2017
Resum:	The present study sought to evaluate the usefulness of EBUS-TBNA in the diagnosis of locoregional recurrence of lung cancer in a cohort of lung cancer patients who were previously treated surgically, and describe our initial experience of EUS-B-FNA in this clinical scenario. We retrospectively studied the clinical records of all patients with a previous surgically-treated lung cancer who were referred to our bronchoscopy unit after suspicion of locoregional recurrence. The diagnostic sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and overall accuracy of EBUS-TBNA for the diagnosis of locoregional recurrence were evaluated. Seventy-three patients were included. EBUS-TBNA confirmed malignancy in 40 patients: 34 confirmed to have locoregional recurrence, six had metachronous tumours. Of the 33 patients with non-malignant EBUS-TBNA; 2 had specific non-malignant diseases, 26 underwent radiological follow up and 5 patients underwent surgery. Of the 26 patients who had radiological follow up; 18 remained stable, three presented thoracic radiological progression and 5 presented extrathoracic progression. Of the 5 patients who underwent surgery; 3 had metachronous tumours, one confirmed to be a true negative and one presented nodal invasion. Seven patients underwent EUS-B-FNA, four of them confirmed to have recurrence. The sensitivity, specificity, NPV, PPV and overall accuracy of EBUS-TBNA for the diagnosis of locoregional recurrence were 80. 9, 100, 69. 2, 100 and 86. 6% respectively. EBUS-TBNA is an accurate procedure for the diagnosis of locoregional recurrence of surgically-treated lung cancer. EUS-B-FNA combined with EBUS-TBNA broads the diagnostic yield of EBUS-TBNA alone.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Lung cancer ; Recurrence ; Surgically-treated ; Endobronchial Ultrasound ; Transbronchial needle aspiration ; Endoscopic ultrasound ; Fine needle aspiration
Publicat a:	BMC Pulmonary Medicine, Vol. 17 (february 2017) , ISSN 1471-2466

DOI: 10.1186/s12890-017-0388-4
PMID: 28241873

8 p, 713.1 KB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
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