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| Pàgina inicial > Articles > Articles publicats > OsDCL1a activation impairs phytoalexin biosynthesis and compromises disease resistance in rice |
| Data: | 2019 |
| Resum: | MicroRNAs (miRNAs) are small non-coding RNAs that act as post-transcriptional regulators of gene expression via sequence-specific cleavage or translational repression of target transcripts. They are transcribed as long single-stranded RNA precursors with unique stem-loop structures that are processed by a DICER-Like (DCL) ribonuclease, typically DCL1, to produce mature miRNAs. Although a plethora of miRNAs have been found to be regulated by pathogen infection in plants, the biological function of most miRNAs remains largely unknown. Here, the contribution of OsDCL1 to rice immunity was investigated. OsDCL1a activation enhances susceptibility to infection by fungal pathogens in rice. Activation of OsDCL1a represses the pathogen-inducible host defence response and negatively regulates diterpenoid phytoalexin production. These findings provide a basis to understand the molecular mechanisms through which OsDCL1a mediates rice immunity. |
| Ajuts: | Ministerio de Economía y Competitividad BIO2012-32838 Ministerio de Economía y Competitividad BIO2015-67212-R Ministerio de Economía y Competitividad SEV-2015-0533 Ministerio de Economía y Competitividad BES-2013-065521 |
| Drets: | Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets. |
| Llengua: | Anglès |
| Document: | Article ; recerca ; Versió acceptada per publicar |
| Matèria: | DICER-Like (DCL) ; Fungal pathogen ; Fusarium fujikuroi ; Innate immunity ; Magnaporthe oryzae ; Methyl viologen ; MicroRNAs ; Oryza sativa ; Oxidative stress ; Phytoalexins ; Rice |
| Publicat a: | Annals of botany, Vol. 123, Issue 1 (January 2019) , p. 79-83, ISSN 1095-8290 |
Postprint 44 p, 4.0 MB |
Appendix 6 p, 1.0 MB |