Web of Science: 11 citations, Scopus: 10 citations, Google Scholar: citations
Joint QTL mapping and gene expression analysis identify positional candidate genes influencing pork quality traits
González Prendes, Rayner (Centre de Recerca en Agrigenòmica)
Quintanilla Aguado, Raquel (Institut de Recerca i Tecnologia Agroalimentàries)
Cánovas Tienda, Ángela (University of Guelph. Department of Animal Biosciences)
Manunza, Arianna (Universitat Autònoma de Barcelona. Departament de Genètica Animal)
Cardoso, Tainã Figueiredo (Centre de Recerca en Agrigenòmica)
Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Noguera Jiménez, José Luis (Institut de Recerca i Tecnologia Agroalimentàries)
Pena i Subirà, Ramona Natacha (Institut de Recerca i Tecnologia Agroalimentàries)
Amills i Eras, Marcel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)

Date: 2017
Abstract: Meat quality traits have an increasing importance in the pig industry because of their strong impact on consumer acceptance. Herewith, we have combined phenotypic and microarray expression data to map loci with potential effects on five meat quality traits recorded in the longissimus dorsi (LD) and gluteus medius (GM) muscles of 350 Duroc pigs, i. e. pH at 24 hours post-mortem (pH24), electric conductivity (CE) and muscle redness (a*), lightness (L*) and yellowness (b*). We have found significant genome-wide associations for CE of LD on SSC4 (-104 Mb), SSC5 (-15 Mb) and SSC13 (-137 Mb), while several additional regions were signifcantly associated with meat quality traits at the chromosome-wide level. There was a low positional concordance between the associatlons found for LD and GM traits, a feature that refiects the existence of differences in the genetic determinism of meat quality phenotypes in these two muscles. The performance of an eQTL search for SNPs mapping to the regions associated with meat quality traits demonstrated that the GM a* SSC3 and pH24 SSC17 QTL display positional concordance with cis-eQTL regulating the expression of several genes with a potential role on muscle metabolism.
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès.
Document: article ; recerca ; publishedVersion
Published in: Scientific reports, Vol. 7 (2017) , art. 39830, ISSN 2045-2322

DOI: 10.1038/srep39830
PMID: 28054563


9 p, 875.1 KB

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Articles > Research articles
Articles > Published articles

 Record created 2019-06-18, last modified 2019-11-06



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