Web of Science: 23 citations, Scopus: 24 citations, Google Scholar: citations
Modeling amyloids in bacteria
Villar Piqué, Anna (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Ventura, Salvador (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")

Date: 2012
Abstract: An increasing number of proteins are being shown to assemble into amyloid structures, self-seeding fibrillar aggregates that may lead to pathological states or play essential biological functions in organisms. Bacterial cell factories have raised as privileged model systems to understand the mechanisms behind amyloid assembly and the cellular fitness cost associated to the formation of these aggregates. In the near future, these bacterial systems will allow implementing high-throughput screening approaches to identify effective modulators of amyloid aggregation.
Grants: Ministerio de Ciencia e Innovación BFU2010-14901
Agència de Gestió d'Ajuts Universitaris i de Recerca 2009/SGR-760
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès
Document: Article ; recerca ; Versió publicada
Subject: Aggregation ; Amyloids ; Bacteria
Published in: Microbial cell factories, Vol. 11 (2012) , art. 166, ISSN 1475-2859

DOI: 10.1186/1475-2859-11-166
PMID: 23272903


3 p, 133.1 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Biotecnologia i de Biomedicina (IBB)
Articles > Research articles
Articles > Published articles

 Record created 2020-06-22, last modified 2023-06-09



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