Benefit of primary percutaneous coronary interventions in the elderly with ST segment elevation myocardial infarction
Fernández-Bergés, Daniel (Instituto Universitario de Investigación Biosanitaria de Extremadura)
Degano, Irene R. (Institut Hospital del Mar d'Investigacions Mèdiques)
Gonzalez Fernandez, Reyes (Infanta Cristina University Hospital)
Subirana, Isaac (Institut Hospital del Mar d'Investigacions Mèdiques)
Vila, Joan (Institut Hospital del Mar d'Investigacions Mèdiques)
Jiménez-Navarro, Manuel (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia))
Pérez-Fernández, Silvia (Institut Hospital del Mar d'Investigacions Mèdiques)
Roqué, Mercé (Hospital Clínic i Provincial de Barcelona)
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Fernández Avilés, F. (Hospital General Universitario Gregorio Marañón)
Mayorga, Antonio (Hospital General Universitario Gregorio Marañón)
Bertomeu-González, Vicente (Hospital Universitario San Juan de Alicante)
Sanchis, Juan (Hospital Clínic Universitari (València))
Rodríguez Esteban, Marcos (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife))
Sanchez-Hidalgo, Antonio (Consorci Sanitari de Terrassa)
Sanchez-Insa, Esther (Hospital Universitario Miguel Servet (Saragossa))
Elorriaga, Ane (Hospital de Basurto (Bilbao, Biscaia))
Abu-Assi, Emad (Hospital Álvaro Cunqueiro (Vigo))
Nuñez, Alberto (Hospital Universitario Fundación Alcorcón)
Garcia Ruiz, Jose Manuel (Hospital Universitario Central de Asturias)
Morrondo Valdeolmillos, Pedro (Hospital Universitario de Donostia (Sant Sebastià, País Basc))
Bosch-Portell, Daniel (Hospital Universitari de Girona Doctor Josep Trueta)
Lekuona, Iñaki (Hospital de Galdakao (Usansolo, Biscaia))
Carrillo-Lopez, Andres (Hospital Universitari Son Espases (Palma de Mallorca, Balears))
Zamora, Alberto (Hospital Comarcal de Blanes)
Vega-Hernandez, Berta (Hospital Universitario de Cabueñes (Gijón))
Alameda Serrano, Javier (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza)
Rubert, Catalina (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears))
Ruiz-Valdepeñas, Luis (Hospital General Universitario de Ciudad Real)
Quintas, Laura (Hospital de Mendaro)
Rodríguez-Padial, Luis (Complejo Hospitalario de Toledo)
Vaquero, Jessica (Arabako Unibertsitate Ospitalea (Vitoria, País Basc))
Martinez Dolz, Luis (Hospital Universitari i Politècnic La Fe (València))
Barrabés, José A.. (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Sánchez-Fernández, Pedro L. (Hospital Clínico Universitario (Salamanca))
Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau)
Martí-Almor, Julio (Institut Hospital del Mar d'Investigacions Mèdiques)
Elosua, Roberto (Universitat de Vic)
Lidon, Rosa-María (Hospital Universitari Vall d'Hebron. Institut de Recerca)
García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Marrugat, Jaume 1954- (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares)
Universitat Autònoma de Barcelona

Date:	2020
Abstract:	Primary percutaneous coronary intervention (P-PCI) has demonstrated its efficacy in patients with ST segment elevation myocardial infarction (STEMI). However, patients with STEMI ≥75 years receive less P-PCI than younger patients despite their higher in-hospital morbimortality. The objective of this analysis was to determine the effectiveness of P-PCI in patients with STEMI ≥75 years. We included 979 patients with STEMI ≥75 years, from the ATención HOspitalaria del Síndrome coronario study, a registry of 8142 consecutive patients with acute coronary syndrome admitted at 31 Spanish hospitals in 2014-2016. We calculated a propensity score (PS) for the indication of P-PCI. Patients that received or not P-PCI were matched by PS. Using logistic regression, we compared the effectiveness of performing P-PCI versus non-performance for the composite primary event, which included death, reinfarction, acute pulmonary oedema or cardiogenic shock during hospitalisation. Of the included patients, 81. 5 % received P-PCI. The matching provided two groups of 169 patients with and without P-PCI. Compared with its non-performance, P-PCI presented a composite event OR adjusted by PS of 0. 55 (95% CI 0. 34 to 0. 89). Receiving a P-PCI was significantly associated with a reduced risk of major intrahospital complications in patients with STEMI aged 75 years or older.
Grants:	Agència de Gestió d'Ajuts Universitaris i de Recerca 2014SGR240 Instituto de Salud Carlos III RD12-0042
Note:	Altres ajuts: Supported by: MARATO TV3 (081630); Red RedIAPP RD06/0018; CP12/03287; CIBER Epidemiología y Salud Pública; CIBERCV de enfermedades Cardiovasculares, Fondo Europeo de Desarrollo Regional (FEDER) (European Regional Development Funds -ERDF-); FIS CP12/03287, FIS 14/00449, FIS PI081327, FIS INTRASALUD PI1101801.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Coronary intervention (PCI) ; Stemi ; Acute coronary syndrome
Published in:	Open Heart, Vol. 7 (august 2020) , ISSN 2053-3624

DOI: 10.1136/openhrt-2019-001169
PMID: 32747454

7 p, 384.6 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles