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Benefit of primary percutaneous coronary interventions in the elderly with ST segment elevation myocardial infarction
Fernández-Bergés, Daniel (Instituto Universitario de Investigación Biosanitaria de Extremadura)
Degano, Irene R (Institut Hospital del Mar d'Investigacions Mèdiques)
Gonzalez Fernandez, Reyes (Infanta Cristina University Hospital)
Subirana, Isaac (Institut Hospital del Mar d'Investigacions Mèdiques)
Vila, Joan (Institut Hospital del Mar d'Investigacions Mèdiques)
Jiménez-Navarro, Manuel (Virgen de la Victoria University Hospital)
Perez-Fernandez, Silvia (Institut Hospital del Mar d'Investigacions Mèdiques)
Roqué, Mercé (Hospital Clinic)
Bayes-Genis, Antoni (Hospital Universitari Germans Trias i Pujol)
Fernandez-Aviles, Francisco (University Hospital Gregorio Marañon)
Mayorga, Antonio (Hospital Universitario Gregorio Marañón, Madrid)
Bertomeu-Gonzalez, Vicente (Hospital Universitario de San Juan)
Sanchis, Juan (Hospital Clinico Universitario, INCLIVA, Universitat de València)
Rodríguez Esteban, Marcos (Hospital Universitario Nuestra Senora de la Candelaria)
Sanchez-Hidalgo, Antonio (Consorci Sanitari de Terrassa)
Sanchez-Insa, Esther (Hospital Universitario Miguel Servet)
Elorriaga, Ane (Hospital Universitario de Basurto, Bilbao)
Abu Assi, Emad (Hospital Álvaro Junqueiro de Vigo, Pontevedra)
Nuñez, Alberto (Hospital Universitario Fundación de Alcorcón)
Garcia Ruiz, Jose Manuel (Hospital Universitario Central de Asturias)
Morrondo Valdeolmillos, Pedro (Hospital Universitario Donostia, San Sebastián)
Bosch-Portell, Daniel (Hospital Universitari de Girona Doctor Josep Trueta)
Lekuona, Iñaki (Hospital Galdakao-Usansolo)
Carrillo-Lopez, Andres (Hospital Universitari Son Espases)
Zamora, Alberto (Hospital Comarcal de Blanes)
Vega-Hernandez, Berta (Hospital Universitario de Cabueñes)
Alameda Serrano, Javier (Hospital Clínico Universitario Lozano Blesa)
Rubert, Catalina (Hospital Son Llàtzer)
Ruiz-Valdepeñas, Luis (Hospital General Universitario de Ciudad Real)
Quintas, Laura (Hospital de Mendaro)
Rodríguez-Padial, Luis (Complejo Hospitalario de Toledo)
Vaquero, Jessica (Hospital Universitario Araba sede Txagorritxu)
Martinez Dolz, Luis (Hospital Universitario La Fe)
Barrabes, Jose A (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Sanchez, Pedro L (Hospital Universitario Salamanca)
Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau)
Martí-Almor, Julio (Institut Hospital del Mar d'Investigacions Mèdiques)
Elosua, Roberto (Universitat de Vic)
Lidon, Rosa-María (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Garcia-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Marrugat, Jaume (CIBER Enfermedades Cardiovasculares (CIBERCV))
Universitat Autònoma de Barcelona

Date: 2020
Abstract: Primary percutaneous coronary intervention (P-PCI) has demonstrated its efficacy in patients with ST segment elevation myocardial infarction (STEMI). However, patients with STEMI ≥75 years receive less P-PCI than younger patients despite their higher in-hospital morbimortality. The objective of this analysis was to determine the effectiveness of P-PCI in patients with STEMI ≥75 years. We included 979 patients with STEMI ≥75 years, from the ATención HOspitalaria del Síndrome coronario study, a registry of 8142 consecutive patients with acute coronary syndrome admitted at 31 Spanish hospitals in 2014-2016. We calculated a propensity score (PS) for the indication of P-PCI. Patients that received or not P-PCI were matched by PS. Using logistic regression, we compared the effectiveness of performing P-PCI versus non-performance for the composite primary event, which included death, reinfarction, acute pulmonary oedema or cardiogenic shock during hospitalisation. Of the included patients, 81. 5 % received P-PCI. The matching provided two groups of 169 patients with and without P-PCI. Compared with its non-performance, P-PCI presented a composite event OR adjusted by PS of 0. 55 (95% CI 0. 34 to 0. 89). Receiving a P-PCI was significantly associated with a reduced risk of major intrahospital complications in patients with STEMI aged 75 years or older.
Note: Altres ajuts: Supported by: MARATO TV3 (081630); Red RedIAPP RD06/0018; CP12/03287; CIBER Epidemiología y Salud Pública; CIBERCV de enfermedades Cardiovasculares, Fondo Europeo de Desarrollo Regional (FEDER) (European Regional Development Funds -ERDF-); FIS CP12/03287, FIS 14/00449, FIS PI081327, FIS INTRASALUD PI1101801.
Note: Número d'acord de subvenció AGAUR/2014SGR240
Note: Número d'acord de subvenció ISCIII/RD12-0042
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès
Document: article ; recerca ; publishedVersion
Subject: Coronary intervention (PCI) ; Stemi ; Acute coronary syndrome
Published in: Open Heart, Vol. 7 (august 2020) , ISSN 2053-3624

DOI: 10.1136/openhrt-2019-001169
PMID: 32747454


7 p, 384.6 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (scientific output) > Health sciences and biosciences > Institut d'Investigació Biomèdica Sant Pau
Articles > Research articles
Articles > Published articles

 Record created 2020-08-24, last modified 2020-11-12



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