Frequency of detection and phylogenetic analysis of Porcine circovirus3 (PCV-3) in healthy primiparous and multiparous sows and their mummified fetuses and stillborn
Saporiti, Viviane (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Martorell, Susanna (Zoetis Manufacturing & Research Spain S.L)
Cruz, Taís Fukuta (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Klaumann, Francini (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Correa-Fiz, Florencia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Balasch, Monica (Zoetis Manufacturing & Research Spain S.L)
Sibila, Marina (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)

Data:	2020
Resum:	Porcine circovirus 3 (PCV-3) has been suggested as a putative causal agent of swine reproductive disease. A number of different studies have pointed out this association, but there is still a lack of information regarding the normal rates of PCV-3 infection in farms with normal reproductive parameters. The objective of the present study was to assess the frequency of PCV-3 detection in primiparous and multiparous sows and in tissues from their respective fetuses from farms with average reproductive parameters. Sera from 57 primiparous and 64 multiparous sows from 3 different farms were collected at two time points. Brain and lung tissues from 49 mummies and 206 stillborn were collected at farrowing. Samples were tested by PCR, and when positive, quantified by quantitative PCR. Thirty-nine complete genomes were obtained and phylogenetically analyzed. All sera from multiparous sows were negative, while 19/57 (33. 3%) primiparous sows were PCV-3 PCR positive. From the 255 tested fetuses, 86 (33. 7%) had at least one tissue positive to PCV-3. The frequency of detection in fetuses from primiparous sows (73/91, 80. 2%) was significantly higher than those from multiparous ones (13/164, 7. 9%). It can be concluded that PCV-3 is able to cause intrauterine infections in absence of overt reproductive disorders.
Nota:	Altres ajuts: INIA/E-RTA2017-00007-00-00
Nota:	Altres ajuts: FAPESP/2017/26649-4
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Porcs ; Virosi ; Malalties ; Mummified fetus ; Stillborn ; Sow ; Porcine circovirus 3 ; Vertical transmission ; Intra-uterine infection
Publicat a:	Pathogens, Vol. 9 Núm. 7 (2020) , p. 533, ISSN 2076-0817

DOI: 10.3390/pathogens9070533
PMID: 32630733

12 p, 778.9 KB

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