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| Pàgina inicial > Articles > Articles publicats > Switchless multiplexing of graphene active sensor arrays for brain mapping |
(Institut Català de Nanociència i Nanotecnologia) (Institut Català de Nanociència i Nanotecnologia) (Institut de Microelectrònica de Barcelona) (Institut de Microelectrònica de Barcelona) (Institut de Microelectrònica de Barcelona) (Universitat Autònoma de Barcelona. Departament de Química) (Universitat Autònoma de Barcelona. Departament de Química) (Institut de Microelectrònica de Barcelona) (Ludwig-Maximilians Universität München. Faculty of Medicine) (Institut de Microelectrònica de Barcelona) (Institut Català de Nanociència i Nanotecnologia) (Institut de Microelectrònica de Barcelona)
| Data: | 2020 |
| Resum: | Sensor arrays used to detect electrophysiological signals from the brain are paramount in neuroscience. However, the number of sensors that can be interfaced with macroscopic data acquisition systems currently limits their bandwidth. This bottleneck originates in the fact that, typically, sensors are addressed individually, requiring a connection for each of them. Herein, we present the concept of frequency-division multiplexing (FDM) of neural signals by graphene sensors. We demonstrate the high performance of graphene transistors as mixers to perform amplitude modulation (AM) of neural signals in situ, which is used to transmit multiple signals through a shared metal line. This technology eliminates the need for switches, remarkably simplifying the technical complexity of state-of-the-art multiplexed neural probes. Besides, the scalability of FDM graphene neural probes has been thoroughly evaluated and their sensitivity demonstrated in vivo. Using this technology, we envision a new generation of high-count conformal neural probes for high bandwidth brain machine interfaces. |
| Ajuts: | European Commission 732032 European Commission 881603 European Commission 785219 Ministerio de Ciencia e Innovación SEV-2017-0706 Ministerio de Ciencia e Innovación FIS2017-85787-R Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-1426 |
| Drets: | Tots els drets reservats.  |
| Llengua: | Anglès |
| Document: | Article ; recerca ; Versió sotmesa a revisió |
| Matèria: | Multiplexing ; Graphene ; Active sensors ; Bioelectronics ; Neural sensing |
| Publicat a: | Nano letters, Vol. 20, issue 5 (May 2020) , p. 3528-3537, ISSN 1530-6992 |
28 p, 1.7 MB |
