 visitant ::
identificació
|
|||||||||||||||
|
Cerca | Lliura | Ajuda | Servei de Biblioteques | Sobre el DDD | Català English Español | |||||||||
| Pàgina inicial > Articles > Articles publicats > Readmissions and complications in breast ductal carcinoma in situ : |
(Institut Hospital del Mar d'Investigacions Mèdiques) (Institut Hospital del Mar d'Investigacions Mèdiques) (Institut Hospital del Mar d'Investigacions Mèdiques) (Hospital del Mar (Barcelona, Catalunya)) (Institut Hospital del Mar d'Investigacions Mèdiques) (Institut Hospital del Mar d'Investigacions Mèdiques) (Institut Hospital del Mar d'Investigacions Mèdiques)| Data: | 2020 |
| Resum: | Population-wide mammographic screening programs aim to reduce breast cancer mortality. However, a broad view of the harms and benefits of these programs is necessary to favor informed decisions, especially in the earliest stages of the disease. Here, we compare the outcomes of patients diagnosed with breast ductal carcinoma in situ in participants and non-participants of a population-based mammographic screening program. A retrospective cohort study of all patients diagnosed with breast ductal carcinoma in situ between 2000 and 2010 within a single hospital. A total of 211 patients were included, and the median follow-up was 8. 4 years. The effect of detection mode (screen-detected and non-screen-detected) on breast cancer recurrences, readmissions, and complications was evaluated through multivariate logistic regression analysis. In the majority of women, breast ductal carcinoma in situ was screen-detected (63. 5%). Screen-detected breast ductal carcinoma in situ was smaller in size compared to those non-screen-detected (57. 53% < 20 mm versus 78. 03%, p = 0. 002). Overall, breast-conserving surgery was the most frequent surgery (86. 26%); however, mastectomy was higher in non-screen-detected breast ductal carcinoma in situ (20. 78% versus 9. 7%, p = 0. 024). Readmissions for mastectomy were more frequent in non-screen-detected breast ductal carcinoma in situ. Psychological complications, such as fatigue, anxiety, and depression, had a prevalence of 15% within our cohort. Risk of readmissions and complications was higher within the non-screen-detected group, as evidenced by an odds ratio = 6. 25 (95% confidence interval = 1. 95-19. 99) for readmissions and an odds ratio = 2. 41 (95% confidence interval = 1. 95-4. 86) for complications. Our findings indicate that women with breast ductal carcinoma in situ breast cancer diagnosed through population-based breast cancer screening program experience a lower risk of readmissions and complications than those diagnosed outside these programs. These findings can help aid women and health professionals make informed decisions regarding screening. |
| Ajuts: | Instituto de Salud Carlos III PI11-01296 Instituto de Salud Carlos III PI15-00098 Instituto de Salud Carlos III PI16-0024 Instituto de Salud Carlos III PI19-00056 Instituto de Salud Carlos III RD16-0001-0013 |
| Drets: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.  |
| Llengua: | Anglès |
| Document: | Article ; recerca ; Versió publicada |
| Matèria: | Breast ductal carcinoma in situ ; Hospital readmission ; Mastectomy ; Patient-relevant outcome ; Screening |
| Publicat a: | Women's Health, Vol. 16 (october 2020) , ISSN 1745-5065 |
