Nomenclature and clinical phenotypes of atopic dermatitis
Girolomoni, Giampiero (University of Verona)
de Bruin-Weller, Marjolein (University Medical Center (Utrecht, Netherlands))
Aoki, Valeria (University of São Paulo School of Medicine)
Kabashima, Kenji (Kyoto University Graduate School of Medicine)
Deleuran, Mette (Aarhus University Hospital (Aarhus, Dinamarca))
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau)
Bansal, Ashish (Regeneron Pharmaceuticals, Inc. (Tarrytown, NY, USA))
Rossi, Ana Beatris (Sanofi Genzyme (Cambridge, Estats Units)))
Universitat Autònoma de Barcelona

Date:	2021
Abstract:	Atopic dermatitis is a heterogeneous disease and resists classification. In this review, we discuss atopic dermatitis nomenclature and identify morphologic phenotypes, which will facilitate correct diagnoses and development of treatment strategies. We support using the term 'atopic dermatitis' rather than eczema, because it describes the allergic background and inflammation ('itis') as drivers of the disease. Atopic dermatitis has many morphologic manifestations that vary by topographic area affected, age, or race and require consideration in differential diagnosis. Different phenotypes based on morphology and topographic location, ethnicity, and age are discussed. A better-defined phenotype identification for atopic dermatitis will facilitate earlier and correct diagnosis of this complex condition and inform selection of the most appropriate treatment choice in an era in which targeted therapies may generate more individualized patient care.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article de revisió ; Article ; Versió publicada
Subject:	Atopic ; Dermatitis ; Eczema ; Nomenclature ; Phenotype ; Treatment
Published in:	Therapeutic Advances in Chronic Disease, Vol. 12 (march 2021) , ISSN 2040-6231

DOI: 10.1177/20406223211002979
PMID: 33854747

20 p, 2.2 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Published articles