Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones
Manzo, Braulio Omar (Hospital Regional de Alta Especialidad del Bajío (Guanajuato, Mèxic))
Cabrera, Jose David (Hospital Regional de Alta Especialidad del Bajío (Guanajuato, Mèxic))
Emiliani, Esteban (Fundació Puigvert)
Sánchez, Hector Manuel (Hospital Regional de Alta Especialidad del Bajío (Guanajuato, Mèxic))
Eisner, Brian Howard (Massachusetts General Hospital (Boston))
Torres, Jose Ernesto (Hospital Regional de Alta Especialidad del Bajío (Guanajuato, Mèxic))
Universitat Autònoma de Barcelona

Data:	2020
Resum:	To assess the effect of the adherence to medical treatment on urinary parameters in the 24-h metabolic study of patients with kidney stones. A retrospective, longitudinal, descriptive, and observational study was carried out by reviewing the hospital electronic medical record from 2014 to 2018. The adherence to drug treatment was measured 6 months after its initiation, and the numerical values of the metabolic studies were compared. Wilcoxon tests were performed to compare the difference before and after treatment. Ninety patients were evaluated, with 73. 3% of adherence. The 180-day overall adherence rate was 61. 2% in patients treated with a single drug and 85. 4% in patients treated with multiple drugs. There is a statistically significant increase in citrate levels in patients with good adherence in comparison with non-adherent patients (p =0. 031 vs. p =0. 528). Medical treatment and dietary measures in patients with kidney stones have an initial impact at 6 months on the values of the main urinary metabolic alterations that predispose to calculi formation; the most significant is seen in those patients with adherence to medical treatment for hypocitraturia.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Kidney stones ; Renal stones ; Metabolic disorders ; Medical treatment ; Citrate ; Oxalate ; Lithiasis
Publicat a:	Asian Journal of Urology, Vol. 8 (august 2020) , p. 275-279, ISSN 2214-3890

DOI: 10.1016/j.ajur.2020.07.002
PMID: 34401334

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