Additive and Dominance Genomic Analysis for Litter Size in Purebred and Crossbred Iberian Pigs
Srihi, Houssemeddine (Instituto Agroalimentario de Aragón)
Noguera, José Luis (Universitat de Lleida. Departament de Producció Animal)
Topayan, Victoria (Universitat Politècnica de València. Departament de Ciència Animal)
Martín de Hijas, Melani (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Ibañez-Escriche, Noelia (Universitat Politècnica de València. Departament de Ciència Animal)
Casellas Vidal, Joaquim (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Vázquez-Gómez, Marta (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Martínez-Castillero, María (Instituto Agroalimentario de Aragón)
Rosas, Juan Pablo (INGA FOOD. Programa de Mejora Genética "Castúa")
Varona, Luis (Instituto Agroalimentario de Aragón)

Data:	2021
Resum:	INGA FOOD S. A. , as a Spanish company that produces and commercializes fattened pigs, has produced a hybrid Iberian sow called CASTÚA by crossing the Retinto and Entrepelado varieties. The selection of the parental populations is based on selection criteria calculated from purebred information, under the assumption that the genetic correlation between purebred and crossbred performance is high; however, these correlations can be less than one because of a GxE interaction or the presence of non-additive genetic effects. This study estimated the additive and dominance variances of the purebred and crossbred populations for litter size, and calculated the additive genetic correlations between the purebred and crossbred performances. The dataset consisted of 2030 litters from the Entrepelado population, 1977 litters from the Retinto population, and 1958 litters from the crossbred population. The individuals were genotyped with a GeneSeek ® GGP Porcine70K HDchip. The model of analysis was a 'biological' multivariate mixed model that included additive and dominance SNP effects. The estimates of the additive genotypic variance for the total number born (TNB) were 0. 248, 0. 282 and 0. 546 for the Entrepelado, Retinto and Crossbred populations, respectively. The estimates of the dominance genotypic variances were 0. 177, 0. 172 and 0. 262 for the Entrepelado, Retinto and Crossbred populations. The results for the number born alive (NBA) were similar. The genetic correlations between the purebred and crossbred performance for TNB and NBA-between the brackets-were 0. 663 in the Entrepelado and 0. 881 in Retinto poplulations. After backsolving to obtain estimates of the SNP effects, the additive genetic variance associated with genomic regions containing 30 SNPs was estimated, and we identified four genomic regions that each explained > 2% of the additive genetic variance in chromosomes (SSC) 6, 8 and 12: one region in SSC6, two regions in SSC8, and one region in SSC12.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Pig ; Iberian ; Additive ; Dominance ; Genetic correlation ; Crossbreeding ; Genomic selection
Publicat a:	Genes, Vol. 13 (december 2021) , ISSN 2073-4425

DOI: 10.3390/genes13010012
PMID: 35052355

10 p, 471.8 KB

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