Prevalence of modifiable factors limiting treatment efficacy of poorly controlled asthma patients : EFIMERA observational study
Ribó González, Paula (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
Molina, Jesús (Centro de Salud Francia, Fuenlabrada)
Calle Rubio, Myriam (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos)
Maiz, Luis (Hospital Universitario Ramón y Cajal (Madrid))
Campo, Carlos (Orion Pharma, Madrid)
Rytilä, Paula (Orion Corporation Orion Pharma)
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau)
Valero, Antonio (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)

Date:	2020
Abstract:	Several modifiable factors leading to poor asthma control have been described. We aimed to determine the proportion of patients with inadequate treatment, adherence to it, or critical mistakes with inhaler technique, and their impact on asthma control. We conducted a cross-sectional multicenter observational study including asthma patients referred from primary to specialist care for the first time. Data collected were adequate prescription according to guidelines, treatment adherence, and disease control. Of the 1682 patients (age 45 ± 17 years, 64. 6% men), 35. 9% showed inadequate prescription, 76. 8% low adherence, and 17% critical mistakes with inhaler technique, with significantly less critical mistakes among Easyhaler users versus other dry powder inhaler users (10. 3 versus 18. 4%; p < 0. 05). Factors related to bad asthma control were inadequate prescription (OR: 3. 65), non-adherence to treatment (OR: 1. 8), and inhaler misuse (OR: 3. 03). A higher number of risk factors were associated with a higher probability of having badly controlled asthma.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Health care ; Medical research
Published in:	NPJ primary care respiratory medicine, Vol. 30 (july 2020) , ISSN 2055-1010

DOI: 10.1038/s41533-020-00189-6
PMID: 32737324

8 p, 719.6 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles