Multidimensional Evaluation of Awareness in Prader-Willi Syndrome
Cobo, Jesus (Societat Catalana de Psiquiatria i Salut Mental (Barcelona, Catalunya))
Coronas, Ramon (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Pousa, Esther (Institut d'Investigació Biomèdica Sant Pau)
Oliva, Joan Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Giménez-Palop, Olga (Universitat Autònoma de Barcelona. Departament de Medicina)
Esteba-Castillo, Susanna (Institut d'Investigació Biomèdica de Girona)
Novell, Ramon (Institut d'Investigació Biomèdica de Girona)
Palao, Diego (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Caixàs i Pedragós, Assumpta (Universitat Autònoma de Barcelona. Departament de Medicina)

Date:	2021
Abstract:	There are no studies about insight or awareness of illness in patients with Prader-Willi Syndrome (PWS). The objective of this study was to explore the level of awareness of the disorder, of the need for medication, and of the social consequences of the disease, as well as of its main symptoms in PWS. We also aimed to explore relationships between awareness and sociodemographic and clinical characteristics, and to compare all data with a matched sample of patients with psychosis. Insight was assessed by an Adapted version of the Scale of Unawareness of Mental Disorder in a cross-sectional pilot study at a University Hospital. Thirty-six individuals with PWS (58. 3% women) were included. Results showed that PWS patients had a good awareness of the illness and of the effects of medication, in contrast to a lack of awareness of illness' social consequences. Awareness of obesity/overweight was excellent, as was the awareness of excessive appetite. Awareness of excessive food intake was only mild. Insight correlated with age and functionality, but not with BMI. PWS patients showed a better insight into the illness but a similar awareness of the effects of the medication and of the social consequences of the disease as compared to schizophrenia-spectrum patients. This profile of insight may have relevant clinical implications.
Grants:	Instituto de Salud Carlos III PI-18/0734
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Prader-Willi Syndrome ; Awareness ; Insight ; Obesity ; BMI ; Functionality
Published in:	Journal of clinical medicine, Vol. 10 (may 2021) , ISSN 2077-0383

DOI: 10.3390/jcm10092007
PMID: 34067179

15 p, 311.0 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles