Women's Health in Multiple Sclerosis : A Scoping Review
Ross, Lindsay (Mellen Center for Multiple Sclerosis Treatment and Research. Department of Neurology)
Ng, Huah Shin (University of British Columbia. Department of Medicine)
O'Mahony, Julia (University of Manitoba. Department of Internal Medicine)
Amato, Maria Pia (University of Florence)
Cohen, Jeffrey A. (Mellen Center for Multiple Sclerosis Treatment and Research. Department of Neurology)
Harnegie, Mary Pat (Cleveland Clinic)
Hellwig, Kerstin (Ruhr University. Department of Neurology)
Tintoré, Mar (Hospital Universitari Vall d'Hebron)
Vukusic, Sandra (Université Claude Bernard Lyon 1)
Marrie, Ruth Ann (University of Manitoba. Department of Community Health Sciences)
Universitat Autònoma de Barcelona

Data:	2022
Resum:	Women with multiple sclerosis (MS) may face challenges related to managing reproduction, pregnancy, and menopause while simultaneously managing their disease. The purpose of this scoping review was to map the literature broadly related to topics relevant to women's health in MS to inform the clinical and research communities about the existing types and sources of evidence and knowledge gaps. Apart from coverage of topics within the field of women's health, we were interested in potential gaps related to geographic and racial and ethnic diversity. We also aimed to understand the degree of inclusion of women with progressive MS in this research. We searched the EMBASE and Ovid Medline databases from 1980 until November 23, 2020. We included case-control and cohort studies, clinical trials and case series published in any language, conducted in women with MS, clinically isolated syndrome, or radiologically isolated syndrome, that addressed women's health. Two reviewers independently screened abstracts and full-text reports for study inclusion, and completed data extraction. Of 112,106 citations screened, 1,041 underwent full-text review and 353 met the inclusion criteria. The number of studies regarding women's health has increased exponentially over time. Almost half of the studies were conducted (at least in part) in Europe, while 21. 7% were conducted in North America; only one study was conducted in Africa. Most studies did not report the race or ethnicity of their participants (n = 308, 87. 2%). Among the 353 studies, 509 topics were reported as some studies addressed more than one topic. Over one-third of these focused on pregnancy (n = 201, 37. 2%), followed by fetal/neonatal outcomes (14. 4%) and sexual dysfunction (10%). Among the 201 studies that focused on pregnancy, only 51 (25. 4%) included participants with progressive MS. This review identifies important knowledge gaps related to women's health in MS and particularly the need for future studies to include participants with a broader range of races and ethnicities, with progressive MS, and living in Asia-Pacific and African regions.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Matèria:	Multiple sclerosis ; Scoping review ; Pregnancy ; Menopause ; Women's health
Publicat a:	Frontiers in neurology, Vol. 12 (january 2022) , ISSN 1664-2295

DOI: 10.3389/fneur.2021.812147
PMID: 35173669

11 p, 1.2 MB

El registre apareix a les col·leccions:
Articles > Articles de recerca
Articles > Articles publicats