The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury : A Case Series
Kreydin, Evgeniy (University of Southern California)
Zhong, Hui (University of California)
Lavrov, Igor (Institute of Kazan Federal University)
Edgerton, Victor (Institut Germans Trias i Pujol. Institut Guttmann)
Gad, Parag (University of California)
Universitat Autònoma de Barcelona

Date:	2022
Abstract:	Spinal cord injury (SCI) is a devastating condition that impacts multiple organ systems. Neurogenic bowel dysfunction (NBD) frequently occurs after a SCI leading to reduced sensation of bowel fullness and bowel movement often leading to constipation or fecal incontinence. Spinal Neuromodulation has been proven to be a successful modality to improve sensorimotor and autonomic function in patients with spinal cord injuries. The pilot data presented here represents the first demonstration of using spinal neuromodulation to activate the anorectal regions of patients with spinal cord injuries and the acute and chronic effects of stimulation. We observed that spinal stimulation induces contractions as well as changes in sensation and pressure profiles along the length of the anorectal region. In addition, we present a case report of a patient with a SCI and the beneficial effect of spinal neuromodulation on the patient's bowel program.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Non-invasive spinal cord stimulation ; Spinal cord injury ; Stroke ; Multiple sclerosis ; Neurogenic bladder ; Overactive bladder urodynamics
Published in:	Frontiers in Neuroscience, Vol. 16 (february 2022) , ISSN 1662-453X

DOI: 10.3389/fnins.2022.816106
PMID: 35250456

7 p, 1.0 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles