Mechanisms of epigenetic regulation of transcription by lncRNAs in plants
Tremblay, Benjamin Jean-Marie (Centre de Recerca en Agrigenòmica)
Qüesta, Julia I. (Centre de Recerca en Agrigenòmica)

Date:	2023
Abstract:	Long noncoding RNAs (lncRNAs) are an ubiquitous feature of eukaryotic genomes and in recent decades have been shown to be highly abundant and varied. Many prominent examples have been described as having essential roles in regulating the expression of genes in different developmental and environmental contexts. As a result, much work has been done on elucidating the mechanisms by which they modulate the expression of protein coding genes. In this review, we focus on those which have been characterized in plants. We specifically examine common epigenetic mechanisms that regulate gene expression at the level of transcription. In this regard, we focus on the lncRNAs in plants that have primarily been associated with controlling the chromatin environment of genes at the level of modifications, RNA POLYMERASE II (RNAPII) processivity and efficiency of transcription, and mediating the formation of transcriptionally activating and repressive chromatin loops. We discuss open questions in plant lncRNA epigenetic regulation and opportunities for future study of functionally significant lncRNAs with yet-unknown epigenetic mechanisms.
Grants:	Ministerio de Economía y Competitividad SEV-2015-0533 Ministerio de Ciencia e Innovación PRE-2019-090156
Note:	Altres ajuts: Junior Leader Fellowship [LCF/BQ/PI19/11690003] from "laCaixa" Foundation [ID100010434]
Rights:	Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.
Language:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Subject:	Chromatin ; Epigenetics ; Gene regulation ; Lncrnas ; Plants ; RNA polymerase
Published in:	IUBMB Life, Vol. 75, Issue 5 (May 2023) , p. 427-439, ISSN 1521-6551

DOI: 10.1002/iub.2681

Postprint 25 p, 701.9 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
Articles > Published articles