Nail Psoriasis Psoriasis ungueal
Canal-García, Elena (Hospital Universitari Arnau de Vilanova)
Bosch-Amate, Xavier (Hospital Clínic i Provincial de Barcelona)
Belinchón, Isabel (Instituto de Investigación Sanitaria y Biomédica de Alicante)
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau)

Date:	2022
Abstract:	Nail involvement in psoriasis is common. It is seen in up to 80% of patients with psoriatic lesions and may be the only manifestation in 6% of cases. Nail psoriasis is correlated with more severe disease, characterized by earlier onset and a higher risk of psoriatic arthritis. Accordingly, it can also result in significant functional impairment and reduced quality of life. Psoriasis involving the nail matrix causes pitting, leukonychia, red lunula and nail dystrophy, while nail bed involvement causes splinter hemorrhages, onycholysis, oil spots (salmon patches), and subungual hyperkeratosis. Common evaluation tools are the Nail Psoriasis Severity Index (NAPSI), the modified NAPSI, and the f-PGA (Physician's Global Assessment of Fingernail Psoriasis). Treatment options include topical therapy, intralesional injections, and systemic and biologic agents. Treatment should therefore be assessed on an individualized basis according to the number of nails involved, the part of the nail or nails affected, and the presence of concomitant nail and/or joint involvement.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Castellà
Document:	Article de revisió ; recerca ; Versió publicada
Subject:	Psoriasis ; Nails ; Nail diseases ; Psoriatic arthritis
Published in:	Actas dermo-sifiliográficas, Vol. 113 Núm. 5 (mayo 2022) , p. 481-490, ISSN 1578-2190

DOI: 10.1016/j.ad.2022.01.006
PMID: 35697407

10 p, 1.5 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles